EN ISO 23702-1:2023

Leather - Per- and polyfluoroalkyl substances - Part 1: Determination of non-volatile compounds by extraction method using liquid chromatography (ISO 23702-1:2023)

This document specifies a test method for detection and quantification of extractable non-volatile per- and polyfluoroalkyl substances (PFAS) in leather and coated leather by solvent extraction and liquid chromatography coupled with mass spectrometry.
This document, taking into account the three-dimensional distribution of the fibres within leather, makes the evaluation of the PFAS with respect to the mass.
PFAS substances categories and applications are listed in Annex A, Table A.1. Classes of PFAS regulated compounds listed in Annex B, Table B.1, include acids, telomers, sulfonates and sulphonamide alcohols. Classes of other non-regulated compounds that can be determined by this document are listed in Annex C, Table C.1.
NOTE 1        By applying the method specified in this document, the concentration of free fluorotelomer alcohols (FTOH) in a sample cannot be correctly quantified if perfluoropolymers that release FTOH due to transesterification with the extraction solvent methanol are present in the sample.
NOTE 2        Some regulations (e.g. Reference [4]) also restrict perfluoropolymers having a linear or branched perfluoroheptyl group with the moiety (C7F15)C as one of the structural elements that can degrade to PFOA, e.g. polymers containing 2-perfluorooctylethanol (8:2 FTOH, CAS Registry Number® 678-39-7) bonded as esters. To determine whether these perfluoropolymers are intentionally present, it could be necessary to introduce an alkaline hydrolysis method to remove the 8:2 FTOH side-chain from the polymer. In addition, other FTOH, e.g. 6:2 FTOH or 10:2 FTOH, will be released from relevant perfluoropolymers by alkaline hydrolysis.

Leder - Per- und Polyfluoralkylsubstanzen - Teil 1: Bestimmung von nichtflüchtigen Verbindungen durch Extraktion mit Flüssigkeitschromatographie (ISO 23702‑1:2023)

Dieses Dokument legt ein Prüfverfahren zum Nachweis und zur quantitativen Bestimmung von extrahierbaren nichtflüchtigen Per- und Polyfluoralkylsubstanzen (PFAS) in Leder und beschichtetem Leder mittels Lösemittelextraktion und Flüssigkeitschromatographie in Verbindung mit Massenspektrometrie fest.
Unter Berücksichtigung der dreidimensionalen Faserverteilung innerhalb des Leders bewertet dieses Dokument die PFAS im Hinblick auf die Masse.
PFAS-Substanzkategorien und  Anwendungen sind in Anhang A, Tabelle A.1, aufgeführt. Die Klassen der regulierten PFAS-Verbindungen, die in Anhang B, Tabelle B.1, aufgeführt sind, schließen Säuren, Telomere, Sulfonate und Sulfon¬amidalkohole ein. Die Klassen anderer, nichtregulierter Verbindungen, die nach diesem Dokument bestimmt werden können, sind in Anhang C, Tabelle C.1, aufgeführt.
ANMERKUNG 1   Bei Anwendung des in diesem Dokument festgelegten Verfahrens kann die Konzentration freier Fluortelomeralkohole (FTOH) in einer Probe nicht korrekt quantifiziert werden, wenn Perfluorpolymere, die FTOH durch Um¬esterung mit dem Extraktionslösemittel Methanol freisetzen, in der Probe vorhanden sind.
ANMERKUNG 2   Einige Verordnungen (z. B. Literaturhinweis [4]) beschränken auch Perfluorpolymere mit einer linearen oder verzweigten Perfluorheptylgruppe mit dem Bestandteil (C7F15)C als einem der Strukturelemente, die zu PFOA abgebaut werden können, z. B. Polymere, die als Ester gebundenes 2 Perfluoroctylethanol (8:2 FTOH, CAS-Registernummer®  678 39 7) enthalten. Um festzustellen, ob die Anwesenheit dieser Perfluorpolymere beabsichtigt ist, könnte die Aufnahme eines alkalischen Hydrolyseverfahrens zur Entfernung der 8:2 FTOH-Seitenkette des Polymers erforderlich sein. Darüber hinaus werden andere FTOH, z. B. 6:2 FTOH oder 10:2 FTOH, durch alkalische Hydrolyse aus entsprechenden Perfluor¬polymeren freigesetzt [3].
WARNUNG — Die Anwendung dieses Dokuments schließt gefährliche Substanzen ein. Es gibt nicht vor, alle mit seiner Anwendung verbundenen Sicherheits- oder Umweltprobleme zu behandeln. Es liegt in der Verantwortung der Personen, die dieses Dokument anwenden, vor dessen Anwendung geeignete Maßnahmen zu ergreifen, um die Sicherheit und Gesundheit von Personal sicherzustellen und die dafür maßgebenden Anforderungen zu erfüllen.

Cuir - Substances perfluoroalkylées et polyfluoroalkylées - Partie 1: Détermination des composés non volatils par une méthode d’extraction utilisant la chromatographie en phase liquide (ISO 23702-1:2023)

Le présent document spécifie une méthode d’essai de détection et de quantification des substances perfluoroalkylées et polyfluoroalkylées (PFAS) extractibles non volatiles dans le cuir et le cuir enduit, en utilisant l’extraction par solvant et la chromatographie en phase liquide couplée à la spectrométrie de masse.
Le présent document, tenant compte de la distribution tridimensionnelle des fibres dans le cuir, réalise l’évaluation des PFAS par rapport à la masse.
Une liste des catégories de substances PFAS et de leurs applications est fournie dans le Tableau A.1 de l’Annexe A. Les classes de composés PFAS réglementés répertoriés dans le Tableau B.1 de l’Annexe B comprennent des acides, des télomères, des sulfonates et des alcools sulfonamides. Les classes d’autres composés non réglementés qui peuvent être déterminés par le présent document sont énumérées dans le Tableau C.1 de l’Annexe C.
NOTE 1        En appliquant la méthode spécifiée dans le présent document, la concentration en alcools de télomères fluorés (FTOH) libres dans un échantillon ne peut pas être déterminée correctement, si des polymères perfluorés qui libèrent des FTOH en raison de la transestérification avec le méthanol utilisé comme solvant d’extraction sont présents dans l’échantillon.
NOTE 2        Certaines réglementations (par exemple, référence [4]) soumettent également à des restrictions les polymères perfluorés ayant, parmi leurs éléments structurels pouvant être dégradés en PFOA, un groupe perfluoroheptyle linéaire ou ramifié avec la fraction (C7F15)C, par exemple des polymères contenant du 2-perfluorooctyléthanol [8:2 FTOH, CAS Registry Number® (numéro d’enregistrement CAS) 678-39-7], lié sous forme d’esters. Afin de déterminer si ces polymères perfluorés sont intentionnellement présents, il peut s’avérer nécessaire d’introduire une méthode d’hydrolyse alcaline pour supprimer la chaîne latérale 8:2 FTOH du polymère. En outre, d’autres FTOH, par exemple 6:2 FTOH ou 10:2 FTOH, seront libérés des polymères perfluorés concernés par l’hydrolyse alcaline.

Usnje - Per- in polifluoroalkil snovi - 1. del: Določevanje nehlapnih spojin z metodo ekstrakcije z uporabo tekoče kromatografije (ISO 23702-1:2023)

Ta dokument določa preskusno metodo za odkrivanje in kvantifikacijo izločljivih nevtralnih, ionskih, dolgoverižnih, srednjeverižnih in kratkoverižnih perfluoriranih in polifluoriranih snovi v usnju in premazanem usnju.
Ta dokument, upoštevajoč tridimenzionalno porazdelitev vlaken v usnju, vrednoti perfluorirane in polifluorirane snovi glede na maso.
Razredi predpisanih spojin, navedenih v preglednici A.1 dodatka A, vključujejo kisline, telomerje, sulfonate in sulfonamid alkohole. Razredi drugih nepredpisanih spojin, ki jih je mogoče določiti s tem dokumentom, so opredeljeni v preglednici B.1 dodatka B.

General Information

• Status: Published
• Publication Date: 27-Jun-2023
• ICS: 59.140.30 - Leather and furs
• Technical Committee: CEN/TC 289 - Leather
• Drafting Committee: CEN/TC 289/WG 1 - Chemical test methods
• Current Stage: 6060 - Definitive text made available (DAV) - Publishing
• Start Date: 28-Jun-2023
• Completion Date: 28-Jun-2023
• Ref Project: SIST EN ISO 23702-1:2023 - Leather - Per- and polyfluoroalkyl substances - Part 1: Determination of non-volatile compounds by extraction method using liquid chromatography (ISO 23702-1:2023)

Relations

• Replaces: EN ISO 23702-1:2018 - Leather - Organic fluorine - Part 1: Determination of non-volatile compounds by extraction method using liquid chromatography/tandem mass spectrometry detector (LC-MS/MS) (ISO 23702-1:2018)
• Effective Date: 21-Jul-2021

Standards Content (Sample)

SLOVENSKI STANDARD
01-september-2023
Usnje - Per- in polifluoroalkil snovi - 1. del: Določevanje nehlapnih spojin z metodo
ekstrakcije z uporabo tekoče kromatografije (ISO 23702-1:2023)
Leather - Per- and polyfluoroalkyl substances - Part 1: Determination of non-volatile
compounds by extraction method using liquid chromatography (ISO 23702-1:2023)
Leder - Per- und Polyfluoralkylsubstanzen - Teil 1: Bestimmung von nichtflüchtigen
Verbindungen durch Extraktion mit Flüssigchromatographie (ISO 23702-1:2023)
Cuir - Substances perfluoroalkylées et polyfluoroalkylées - Partie 1: Détermination des
composés non volatils par une méthode d’extraction utilisant la chromatographie en
phase liquide (ISO 23702-1:2023)
Ta slovenski standard je istoveten z: EN ISO 23702-1:2023
ICS:
59.140.30 Usnje in krzno Leather and furs
2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.

EN ISO 23702-1
EUROPEAN STANDARD
NORME EUROPÉENNE
June 2023
EUROPÄISCHE NORM
ICS 59.140.30 Supersedes EN ISO 23702-1:2018
English Version
Leather - Per- and polyfluoroalkyl substances - Part 1:
Determination of non-volatile compounds by extraction
method using liquid chromatography (ISO 23702-1:2023)
Cuir - Substances perfluoroalkylées et Leder - Per- und Polyfluoralkylsubstanzen - Teil 1:
polyfluoroalkylées - Partie 1: Détermination des Bestimmung von nichtflüchtigen Verbindungen durch
composés non volatils par une méthode d'extraction Extraktion mit Flüssigchromatographie (ISO 23702-
utilisant la chromatographie en phase liquide (ISO 1:2023)
23702-1:2023)
This European Standard was approved by CEN on 19 June 2023.

CEN members are bound to comply with the CEN/CENELEC Internal Regulations which stipulate the conditions for giving this
European Standard the status of a national standard without any alteration. Up-to-date lists and bibliographical references
concerning such national standards may be obtained on application to the CEN-CENELEC Management Centre or to any CEN
member.
This European Standard exists in three official versions (English, French, German). A version in any other language made by
translation under the responsibility of a CEN member into its own language and notified to the CEN-CENELEC Management
Centre has the same status as the official versions.

CEN members are the national standards bodies of Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia,
Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway,
Poland, Portugal, Republic of North Macedonia, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Türkiye and
United Kingdom.
EUROPEAN COMMITTEE FOR STANDARDIZATION
COMITÉ EUROPÉEN DE NORMALISATION

EUROPÄISCHES KOMITEE FÜR NORMUNG

CEN-CENELEC Management Centre: Rue de la Science 23, B-1040 Brussels
© 2023 CEN All rights of exploitation in any form and by any means reserved Ref. No. EN ISO 23702-1:2023 E
worldwide for CEN national Members.

Contents Page
European foreword . 3

European foreword
This document (EN ISO 23702-1:2023) has been prepared by Technical Committee ISO/IULTCS
"International Union of Leather Technologists and Chemists Societies" in collaboration with Technical
Committee CEN/TC 289 “Leather” the secretariat of which is held by UNI.
This European Standard shall be given the status of a national standard, either by publication of an
identical text or by endorsement, at the latest by December 2023, and conflicting national standards
shall be withdrawn at the latest by December 2023.
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. CEN shall not be held responsible for identifying any or all such patent rights.
This document supersedes EN ISO 23702-1:2018.
Any feedback and questions on this document should be directed to the users’ national standards
body/national committee. A complete listing of these bodies can be found on the CEN website.
According to the CEN-CENELEC Internal Regulations, the national standards organizations of the
following countries are bound to implement this European Standard: Austria, Belgium, Bulgaria,
Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland,
Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Republic of
North Macedonia, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Türkiye and the
United Kingdom.
Endorsement notice
The text of ISO 23702-1:2023 has been approved by CEN as EN ISO 23702-1:2023 without any
modification.
INTERNATIONAL ISO
STANDARD 23702-1
IULTCS
IUC 39-1
Second edition
2023-06
Leather — Per- and polyfluoroalkyl
substances —
Part 1:
Determination of non-volatile
compounds by extraction method
using liquid chromatography
Cuir — Substances perfluoroalkylées et polyfluoroalkylées —
Partie 1: Détermination des composés non volatils par une méthode
d’extraction utilisant la chromatographie en phase liquide
Reference numbers
ISO 23702-1:2023(E)
IULTCS/IUC 39-1:2023(E)
ISO 23702-1:2023(E)
IULTCS/IUC 39-1:2023(E)
© ISO 2023
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may
be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting on
the internet or an intranet, without prior written permission. Permission can be requested from either ISO at the address below
or ISO’s member body in the country of the requester.
ISO copyright office
CP 401 • Ch. de Blandonnet 8
CH-1214 Vernier, Geneva
Phone: [phone]
Email: [e-mail]
Website: www.iso.org
Published in Switzerland
ii
ISO 23702-1:2023(E)
IULTCS/IUC 39-1:2023(E)
Contents Page
Foreword .iv
Introduction . vi
1  Scope . 1
2  Normative references . 1
3  Terms and definitions . 2
4  Principle . 2
5  Reagents . 2
6  Apparatus . 3
7  Sampling . 4
8  Procedure .4
9  Expression of results . 5
9.1 Calibration . 5
9.2 Calculation of the result . 5
9.3 Calculation of the results of a sum . 5
9.4 Precision . . . 6
10 Test report . 6
Annex A (informative)  PFAS substance categories and applications . 7
Annex B (informative)  PFAS regulated substances . 8
Annex C (informative)  PFAS non-regulated substances .11
Annex D (informative)  Usable ions and possible quantification limits for PFAS analysis by
LC-MS/MS .12
Annex E (informative)  LC-MS/MS chromatographic conditions .14
Annex F (informative)  Interferences.22
Annex G (informative)  Accuracy .23
Bibliography .25
iii
ISO 23702-1:2023(E)
IULTCS/IUC 39-1:2023(E)
Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards
bodies (ISO member bodies). The work of preparing International Standards is normally carried out
through ISO technical committees. Each member body interested in a subject for which a technical
committee has been established has the right to be represented on that committee. International
organizations, governmental and non-governmental, in liaison with ISO, also take part in the work.
ISO collaborates closely with the International Electrotechnical Commission (IEC) on all matters of
electrotechnical standardization.
The procedures used to develop this document and those intended for its further maintenance are
described in the ISO/IEC Directives, Part 1. In particular, the different approval criteria needed for the
different types of ISO documents should be noted. This document was drafted in accordance with the
editorial rules of the ISO/IEC Directives, Part 2 (see www.iso.org/directives).
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. ISO shall not be held responsible for identifying any or all such patent rights. Details of
any patent rights identified during the development of the document will be in the Introduction and/or
on the ISO list of patent declarations received (see www.iso.org/patents).
Any trade name used in this document is information given for the convenience of users and does not
constitute an endorsement.
For an explanation of the voluntary nature of standards, the meaning of ISO specific terms and
expressions related to conformity assessment, as well as information about ISO's adherence to
the World Trade Organization (WTO) principles in the Technical Barriers to Trade (TBT), see
www.iso.org/iso/foreword.html.
IULTCS, originally formed in 1897, is a world-wide organization of professional leather societies to
further the advancement of leather science and technology. IULTCS has three Commissions, which
are responsible for establishing international methods for the sampling and testing of leather. ISO
recognizes IULTCS as an international standardizing body for the preparation of test methods for
leather.
This document was prepared by the Chemical Test Commission of the International Union of Leather
Technologists and Chemists Societies (IUC Commission, IULTCS), in collaboration with the European
Committee for Standardization (CEN) Technical Committee CEN/TC 289, Leather, in accordance with
the Agreement on technical cooperation between ISO and CEN (Vienna Agreement).
This second edition cancels and replaces the first edition (ISO 23702-1:2018), which has b
...