ISO 6401:2022

Plastics — Poly(vinyl chloride) — Determination of residual vinyl chloride monomer using gas-chromatographic method

This document specifies a method for the determination of vinyl chloride monomer in homopolymer and copolymer resins of vinyl chloride and compounded materials. The method is based on sample dissolution and headspace gas chromatography. Concentrations of vinyl chloride in the range 0,1 mg/kg to 3,0 mg/kg can be determined.

Plastiques — Poly(chlorure de vinyle) — Détermination du chlorure de vinyle monomère résiduel par la méthode de chromatographie en phase gazeuse

Le présent document spécifie une méthode de détermination de la teneur en chlorure de vinyle monomère dans les résines d’homopolymères et de copolymères de chlorure de vinyle et matériaux composés. Cette méthode repose sur la dissolution de l’échantillon et sur la chromatographie en phase gazeuse à espace de tête. La concentration en chlorure de vinyle peut être déterminée dans la plage de 0,1 mg/kg à 3,0 mg/kg.

General Information

• Status: Published
• Publication Date: 08-Dec-2022
• ICS: 83.080.20 - Thermoplastic materials
• Technical Committee: ISO/TC 61/SC 5 - Physical-chemical properties
• Drafting Committee: ISO/TC 61/SC 5 - Physical-chemical properties
• Current Stage: 6060 - International Standard published
• Start Date: 09-Dec-2022
• Due Date: 22-Sep-2024
• Completion Date: 09-Dec-2022

Relations

• Revises: ISO 6401:2008 - Plastics — Poly(vinyl chloride) — Determination of residual vinyl chloride monomer — Gas-chromatographic method
• Effective Date: 06-Jun-2022

Standards Content (Sample)

INTERNATIONAL ISO
STANDARD 6401
Third edition
2022-12
Plastics — Poly(vinyl chloride) —
Determination of residual vinyl
chloride monomer using gas-
chromatographic method
Reference number
ISO 6401:2022(E)
© ISO 2022

---------------------- Page: 1 ----------------------
ISO 6401:2022(E)
COPYRIGHT PROTECTED DOCUMENT
© ISO 2022
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may
be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting on
the internet or an intranet, without prior written permission. Permission can be requested from either ISO at the address below
or ISO’s member body in the country of the requester.
ISO copyright office
CP 401 • Ch. de Blandonnet 8
CH-1214 Vernier, Geneva
Phone: [phone]
Email: [e-mail]
Website: www.iso.org
Published in Switzerland
ii
  © ISO 2022 – All rights reserved

---------------------- Page: 2 ----------------------
ISO 6401:2022(E)
Contents Page
Foreword .iv
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Principle . 1
5 Sampling . 1
6 Apparatus . 1
7 Reagents and materials . 2
8 Procedure .3
8.1 Preparation of test solutions . . 3
8.2 Gas chromatography . 3
8.3 Determination . 3
8.4 Preparation of the calibration graph . 4
9 Calculation . 4
10 Precision . 4
11 Test report . 4
Annex A (informative) Suitable GC columns for the determination of vinyl chloride
monomer . 6
Annex B (informative) Typical responses for vinyl chloride monomer calibration solutions.7
Bibliography . 8
iii
© ISO 2022 – All rights reserved

---------------------- Page: 3 ----------------------
ISO 6401:2022(E)
Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards
bodies (ISO member bodies). The work of preparing International Standards is normally carried out
through ISO technical committees. Each member body interested in a subject for which a technical
committee has been established has the right to be represented on that committee. International
organizations, governmental and non-governmental, in liaison with ISO, also take part in the work.
ISO collaborates closely with the International Electrotechnical Commission (IEC) on all matters of
electrotechnical standardization.
The procedures used to develop this document and those intended for its further maintenance are
described in the ISO/IEC Directives, Part 1. In particular, the different approval criteria needed for the
different types of ISO documents should be noted. This document was drafted in accordance with the
editorial rules of the ISO/IEC Directives, Part 2 (see www.iso.org/directives).
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. ISO shall not be held responsible for identifying any or all such patent rights. Details of
any patent rights identified during the development of the document will be in the Introduction and/or
on the ISO list of patent declarations received (see www.iso.org/patents).
Any trade name used in this document is information given for the convenience of users and does not
constitute an endorsement.
For an explanation of the voluntary nature of standards, the meaning of ISO specific terms and
expressions related to conformity assessment, as well as information about ISO's adherence to
the World Trade Organization (WTO) principles in the Technical Barriers to Trade (TBT), see
www.iso.org/iso/foreword.html.
This document was prepared by Technical Committee ISO/TC 61, Plastics, Subcommittee SC 5, Physical-
chemical properties, in collaboration with the European Committee for Standardization (CEN) Technical
Committee CEN/TC 249, Plastics, in accordance with the Agreement on technical cooperation between
ISO and CEN (Vienna Agreement).
This third edition cancels and replaces the second edition (ISO 6401:2008), which has been technically
revised.
The main changes are as follows:
— a reference for the density of N,N'-dimethylacetamide has been added;
— the condition for storing vinyl chloride standard solutions has been specified more precisely;
— the formula for the expression of the vinyl chloride content in relation to the amount of resin has
been corrected;
— the test report has been extended.
Any feedback or questions on this document should be directed to the user’s national standards body. A
complete listing of these bodies can be found at www.iso.org/members.html.
iv
  © ISO 2022 – All rights reserved

---------------------- Page: 4 ----------------------
INTERNATIONAL STANDARD ISO 6401:2022(E)
Plastics — Poly(vinyl chloride) — Determination
of residual vinyl chloride monomer using gas-
chromatographic method
SAFETY PRECAUTIONS — Persons using this document should be familiar with normal laboratory
practice, if applicable. This document does not purport to address all of the safety concerns, if
any, associated with its use. It is the responsibility of the user to establish appropriate safety
and health practices and to determine applicability of any regulatory requirements.
1 Scope
This document specifies a method for the determination of vinyl chloride monomer in homopolymer
and copolymer resins of vinyl chloride and compounded materials. The method is based on sample
dissolution and headspace gas chromatography. Concentrations of vinyl chloride in the range 0,1 mg/
kg to 3,0 mg/kg can be determined.
2 Normative references
The following documents are referred to in the text in such a way that some or all of their content
constitutes requirements of this document. For dated references, only the edition cited applies. For
undated references, the latest edition of the referenced document (including any amendments) applies.
ISO 472, Plastics — Vocabulary
3 Terms and definitions
For the purposes of this document, the terms and definitions given in ISO 472 apply.
ISO and IEC maintain terminology databases for use in standardization at the following addresses:
— ISO Online browsing platform: available at https:// www .iso .org/ obp
— IEC Electropedia: available at https:// www .electropedia .org/
4 Principle
The level of vinyl chloride monomer is determined by headspace gas
...

NORME ISO
INTERNATIONALE 6401
Troisième édition
2022-12
Plastiques — Poly(chlorure de vinyle)
— Détermination du chlorure de
vinyle monomère résiduel par la
méthode de chromatographie en
phase gazeuse
Plastics — Poly(vinyl chloride) — Determination of residual vinyl
chloride monomer using gas-chromatographic method
Numéro de référence
ISO 6401:2022(F)
© ISO 2022

---------------------- Page: 1 ----------------------
ISO 6401:2022(F)
DOCUMENT PROTÉGÉ PAR COPYRIGHT
© ISO 2022
Tous droits réservés. Sauf prescription différente ou nécessité dans le contexte de sa mise en œuvre, aucune partie de cette
publication ne peut être reproduite ni utilisée sous quelque forme que ce soit et par aucun procédé, électronique ou mécanique,
y compris la photocopie, ou la diffusion sur l’internet ou sur un intranet, sans autorisation écrite préalable. Une autorisation peut
être demandée à l’ISO à l’adresse ci-après ou au comité membre de l’ISO dans le pays du demandeur.
ISO copyright office
Case postale 401 • Ch. de Blandonnet 8
CH-1214 Vernier, Genève
Tél.: [phone]
E-mail: [e-mail]
Web: www.iso.org
Publié en Suisse
ii
  © ISO 2022 – Tous droits réservés

---------------------- Page: 2 ----------------------
ISO 6401:2022(F)
Sommaire Page
Avant-propos .iv
1 Domaine d’application . 1
2 Références normatives .1
3 Termes et définitions . 1
4 Principe. 1
5 Échantillonnage .1
6 Appareillage . 2
7 Réactifs et matériaux . 2
8 Mode opératoire . 3
8.1 Préparation des solutions pour essai . 3
8.2 Chromatographie en phase gazeuse . 4
8.3 Détermination . 4
8.4 Préparation de la courbe d’étalonnage . 4
9 Calcul . 4
10 Fidélité . 5
11 Rapport d’essai .5
Annexe A (informative) Colonnes de chromatographie en phase gazeuse appropriées pour
la détermination du chlorure de vinyle monomère . 6
Annexe B (informative) Réponses types pour les solutions d’étalonnage du chlorure
de vinyle monomère . 7
Bibliographie . 8
iii
© ISO 2022 – Tous droits réservés

---------------------- Page: 3 ----------------------
ISO 6401:2022(F)
Avant-propos
L'ISO (Organisation internationale de normalisation) est une fédération mondiale d'organismes
nationaux de normalisation (comités membres de l'ISO). L'élaboration des Normes internationales est
en général confiée aux comités techniques de l'ISO. Chaque comité membre intéressé par une étude
a le droit de faire partie du comité technique créé à cet effet. Les organisations internationales,
gouvernementales et non gouvernementales, en liaison avec l'ISO participent également aux travaux.
L'ISO collabore étroitement avec la Commission électrotechnique internationale (IEC) en ce qui
concerne la normalisation électrotechnique.
Les procédures utilisées pour élaborer le présent document et celles destinées à sa mise à jour sont
décrites dans les Directives ISO/IEC, Partie 1. Il convient, en particulier, de prendre note des différents
critères d'approbation requis pour les différents types de documents ISO. Le présent document a
été rédigé conformément aux règles de rédaction données dans les Directives ISO/IEC, Partie 2 (voir
www.iso.org/directives).
L'attention est attirée sur le fait que certains des éléments du présent document peuvent faire l'objet de
droits de propriété intellectuelle ou de droits analogues. L'ISO ne saurait être tenue pour responsable
de ne pas avoir identifié de tels droits de propriété et averti de leur existence. Les détails concernant
les références aux droits de propriété intellectuelle ou autres droits analogues identifiés lors de
l'élaboration du document sont indiqués dans l'Introduction et/ou dans la liste des déclarations de
brevets reçues par l'ISO (voir www.iso.org/brevets).
Les appellations commerciales éventuellement mentionnées dans le présent document sont données
pour information, par souci de commodité, à l’intention des utilisateurs et ne sauraient constituer un
engagement.
Pour une explication de la nature volontaire des normes, la signification des termes et expressions
spécifiques de l'ISO liés à l'évaluation de la conformité, ou pour toute information au sujet de l'adhésion
de l'ISO aux principes de l’Organisation mondiale du commerce (OMC) concernant les obstacles
techniques au commerce (OTC), voir www.iso.org/avant-propos.
Le présent document a été élaboré par le comité technique ISO/TC 61, Plastiques, sous-comité SC 5,
Propriétés physicochimiques, en collaboration avec le comité technique CEN/TC 249, Plastiques, du
Comité européen de normalisation (CEN), conformément à l’Accord de coopération technique entre
l’ISO et le CEN (Accord de Vienne).
Cette troisième édition annule et remplace la deuxième édition (ISO 6401:2008), qui a fait l’objet d’une
révision technique.
Les principales modifications sont les suivantes:
— une référence à la masse volumique du N,N’-diméthylacétamide a été ajoutée;
— les conditions de conservation des solutions étalons de chlorure de vinyle ont été spécifiées plus
précisément;
— la formule pour l’expression de la teneur en chlorure de vinyle en relation avec la quantité de résine
a été corrigée;
— le rapport d’essai a été élargi.
Il convient que l’utilisateur adresse tout retour d’information ou toute question concernant le présent
document à l’organisme national de normalisation de son pays. Une liste exhaustive desdits organismes
se trouve à l’adresse www.iso.org/fr/members.html.
iv
  © ISO 2022 – Tous droits réservés

---------------------- Page: 4 ----------------------
NORME INTERNATIONALE ISO 6401:2022(F)
Plastiques — Poly(chlorure de vinyle) — Détermination du
chlorure de vinyle monomère résiduel par la méthode de
chromatographie en phase gazeuse
PRÉCAUTIONS DE SÉCURITÉ — Il convient que les personnes utilisant le présent document soient
familières avec les pratiques courantes de laboratoire, le cas échéant. Le présent document n’a
pas pour but de traiter tous les problèmes de sécurité éventuels qui sont liés à son utilisation.
Il incombe à l’utilisateur d’établir des pratiques d’hygiène et de sécurité appropriées et de
déterminer l’applicabilité des exigences réglementaires.
1 Domaine d’application
Le présent document spécifie une méthode de détermination de la teneur en chlorure de vinyle
monomère dans les résines d’homopolymères et de copolymères de chlorure de vinyle et matériaux
composés. Cette méthode repose sur la dissolution de l’échantillon et sur la chromatographie en phase
gazeuse à espace de tête. La concentration en chlorure de vinyle peut être déterminée dans la plage de
0,1 mg/kg à 3,0 mg/kg.
2 Références normatives
Les documents suivants sont cités dans le texte de sorte qu’ils constituent, pour tout ou partie de leur
contenu, des exigences du présent document. Pour les références datées, seule l’édition citée s’applique.
Pour les références non datées, la dernière édition du document de référence s’applique (y compris les
éventuels amendements).
ISO 472, Plastiques — Vocabulaire
3 Termes et définitions
Pour les besoins du présent document, les termes et définitions donnés dans l’ISO 472 s’appliquent.
L’ISO et l’IEC tiennent à jour des bases de données terminologiques destinées à être utilisées en
normalisation, consultables aux adresses suivantes:
— ISO Online browsing platform: disponible à l’adresse https:// www .iso .org/ obp
— IEC Electropedia: disponible à l’adresse https:// www .electropedia .org/
4 Principe
Le niveau de chlorure de vinyle monomère est déterminé par chromatographie en phase gazeuse à
espace de tête de l’échantillon pour essai du polymère dissous ou gonflé dans du N,N’-diméthylacétamide.
5 Échantillonnage
En raison de la volatilité du chlorure de vinyle, un gradient de concentration peut se former sur les
échantillons de résine accumulés. Il est recommandé de refroidir l’échantillon avant de procéder
à l’échantillonnage, il faut cependant éviter la condensation de l’humidité. La préparation des
échantillons do
...

2022-10
ISO 6401:2022(E)
ISO TC 61/SC 5
2022-10-25
Secretariat: DIN
Plastics — Poly(vinyl chloride) — Determination of residual vinyl chloride
monomer using gas-chromatographic method
Plastiques — Poly(chlorure de vinyle) — Détermination du chlorure de vinyle monomère
résiduel par méthode de chromatographie en phase gazeuse

---------------------- Page: 1 ----------------------
ISO/DIS 6401:2022(E)
© ISO 2022
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no
part of this publication may be reproduced or utilized otherwise in any form or by any means,
electronic or mechanical, including photocopying, or posting on the internet or an intranet, without
prior written permission. Permission can be requested from either ISO at the address below or
ISO’s member body in the country of the requester.
ISO copyright office
CP 401 • Ch. de Blandonnet 8
CH-1214 Vernier, Geneva
Phone: [phone]
Email: [e-mail]
Website: www.iso.orgwww.iso.org
Published in Switzerland
2 © ISO 2022 – All rights reserved
ii © ISO 2022 – All rights reserved

---------------------- Page: 2 ----------------------
ISO/DIS 6401:2022(E)
Contents
Foreword . iv
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Principle . 1
5 Sampling . 1
6 Apparatus . 1
7 Reagents and materials . 2
8 Procedure . 3
8.1 Preparation of test solutions . 3
8.2 Gas chromatography . 3
8.3 Determination . 3
8.4 Preparation of the calibration graph . 3
9 Calculation . 4
10 Precision . 4
11 Test report . 4
Annex A (informative) Suitable GC columns for the determination of vinyl chloride
monomer . 5
Annex B (informative) Typical responses for vinyl chloride monomer calibration solutions . 6
Foreword . iv
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Principle . 1
5 Sampling . 1
6 Apparatus . 1
7 Reagents and materials . 2
© ISO 2022 – All rights reserved 3
© ISO 2022 – All rights reserved iii

---------------------- Page: 3 ----------------------
ISO/DIS 6401:2022(E)
8 Procedure . 3
8.1 Preparation of test solutions . 3
8.2 Gas chromatography. 3
8.3 Determination . 3
8.4 Preparation of the calibration graph . 3
9 Calculation . 4
10 Precision . 4
11 Test report . 4
Annex A (informative) Suitable GC columns for the determination of vinyl chloride
monomer . 5
Annex B (informative) Typical responses for vinyl chloride monomer calibration solutions . 6

4 © ISO 2022 – All rights reserved
iv © ISO 2022 – All rights reserved

---------------------- Page: 4 ----------------------
ISO/DIS 6401:2022(E)
Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards
bodies (ISO member bodies). The work of preparing International Standards is normally carried out
through ISO technical committees. Each member body interested in a subject for which a technical
committee has been established has the right to be represented on that committee. International
organizations, governmental and non-governmental, in liaison with ISO, also take part in the work. ISO
collaborates closely with the International Electrotechnical Commission (IEC) on all matters of
electrotechnical standardization.
The procedures used to develop this document and those intended for its further maintenance are
described in the ISO/IEC Directives, Part 1. In particular, the different approval criteria needed for the
different types of ISO documents should be noted. This document was drafted in accordance with the
editorial rules of the ISO/IEC Directives, Part 2 (see www.iso.org/directiveswww.iso.org/directives).
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. ISO shall not be held responsible for identifying any or all such patent rights. Details of any
patent rights identified during the development of the document will be in the Introduction and/or on
the ISO list of patent declarations received (see www.iso.org/patentswww.iso.org/patents).
Any trade name used in this document is information given for the convenience of users and does not
constitute an endorsement.
For an explanation of the voluntary nature of standards, the meaning of ISO specific terms and
expressions related to conformity assessment, as well as information about ISO's adherence to the World
Trade Organization (WTO) principles in the Technical Barriers to Trade (TBT), see
www.iso.org/iso/foreword.htmlwww.iso.org/iso/foreword.html.
This document was prepared by Technical Committee ISO/TC 61, Plastics, Subcommittee SC 5, Physical-
chemical properties, in collaboration with the European Committee for Standardization (CEN) Technical
Committee CEN/TC 249, Plastics, in accordance with the Agreement on technical cooperation between
ISO and CEN (Vienna Agreement).
This third edition cancels and replaces the second edition (ISO 6401:2008), which has been technically
revised.
The main changes are as follows:
— a reference for the density of N,N'-dimethylacetamide has been added;
— the condition for storing vinyl chloride standard solutions has been specified more precisely;
— the formula for the expression of the vinyl chloride content in relation to the amount of resin has
been corrected;
— the test report has been extended.
© ISO 2022 – All rights reserved 5
© ISO 2022 – All rights reserved v

---------------------- Page: 5 ----------------------
ISO/DIS 6401:2022(E)
Any feedback or questions on this document should be directed to the user’s national standards body. A
complete listing of these bodies can be found at
www.iso.org/members.htmlwww.iso.org/members.html.

6 © ISO 2022 – All rights reserved
vi © ISO 2022 – All rights reserved

---------------------- Page: 6 ----------------------
INTERNATIONAL STANDARD ISO 6401:2022(E)

Plastics — Poly(vinyl chloride) — Determination of residual vinyl
chloride monomer using gas-chromatographic method
SAFETY PRECAUTIONS — Persons using this document should be familiar with normal laboratory
practice, if applicable. This document does not purport to address all of the safety concerns, if any,
associated with its use. It is the responsibility of the user to establish appropriate safety and health
practices and to determine applicability of any regulatory requirements.
1 Scope
This document specifies a method for the determination of vinyl chloride monomer in homopolymer and
copolymer resi
...

INTERNATIONAL ISO
STANDARD 6401
Third edition
Plastics — Poly(vinyl chloride) —
Determination of residual vinyl
chloride monomer using gas-
chromatographic method
PROOF/ÉPREUVE
Reference number
ISO 6401:2022(E)
© ISO 2022

---------------------- Page: 1 ----------------------
ISO 6401:2022(E)
COPYRIGHT PROTECTED DOCUMENT
© ISO 2022
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may
be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting on
the internet or an intranet, without prior written permission. Permission can be requested from either ISO at the address below
or ISO’s member body in the country of the requester.
ISO copyright office
CP 401 • Ch. de Blandonnet 8
CH-1214 Vernier, Geneva
Phone: [phone]
Email: [e-mail]
Website: www.iso.org
Published in Switzerland
ii
PROOF/ÉPREUVE © ISO 2022 – All rights reserved

---------------------- Page: 2 ----------------------
ISO 6401:2022(E)
Contents Page
Foreword .iv
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Principle . 1
5 Sampling . 1
6 Apparatus . 1
7 Reagents and materials . 2
8 Procedure .3
8.1 Preparation of test solutions . . 3
8.2 Gas chromatography . 3
8.3 Determination . 3
8.4 Preparation of the calibration graph . 4
9 Calculation . 4
10 Precision . 4
11 Test report . 4
Annex A (informative) Suitable GC columns for the determination of vinyl chloride
monomer . 6
Annex B (informative) Typical responses for vinyl chloride monomer calibration solutions.7
Bibliography . 8
iii
© ISO 2022 – All rights reserved PROOF/ÉPREUVE

---------------------- Page: 3 ----------------------
ISO 6401:2022(E)
Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards
bodies (ISO member bodies). The work of preparing International Standards is normally carried out
through ISO technical committees. Each member body interested in a subject for which a technical
committee has been established has the right to be represented on that committee. International
organizations, governmental and non-governmental, in liaison with ISO, also take part in the work.
ISO collaborates closely with the International Electrotechnical Commission (IEC) on all matters of
electrotechnical standardization.
The procedures used to develop this document and those intended for its further maintenance are
described in the ISO/IEC Directives, Part 1. In particular, the different approval criteria needed for the
different types of ISO documents should be noted. This document was drafted in accordance with the
editorial rules of the ISO/IEC Directives, Part 2 (see www.iso.org/directives).
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. ISO shall not be held responsible for identifying any or all such patent rights. Details of
any patent rights identified during the development of the document will be in the Introduction and/or
on the ISO list of patent declarations received (see www.iso.org/patents).
Any trade name used in this document is information given for the convenience of users and does not
constitute an endorsement.
For an explanation of the voluntary nature of standards, the meaning of ISO specific terms and
expressions related to conformity assessment, as well as information about ISO's adherence to
the World Trade Organization (WTO) principles in the Technical Barriers to Trade (TBT), see
www.iso.org/iso/foreword.html.
This document was prepared by Technical Committee ISO/TC 61, Plastics, Subcommittee SC 5, Physical-
chemical properties, in collaboration with the European Committee for Standardization (CEN) Technical
Committee CEN/TC 249, Plastics, in accordance with the Agreement on technical cooperation between
ISO and CEN (Vienna Agreement).
This third edition cancels and replaces the second edition (ISO 6401:2008), which has been technically
revised.
The main changes are as follows:
— a reference for the density of N,N'-dimethylacetamide has been added;
— the condition for storing vinyl chloride standard solutions has been specified more precisely;
— the formula for the expression of the vinyl chloride content in relation to the amount of resin has
been corrected;
— the test report has been extended.
Any feedback or questions on this document should be directed to the user’s national standards body. A
complete listing of these bodies can be found at www.iso.org/members.html.
iv
PROOF/ÉPREUVE © ISO 2022 – All rights reserved

---------------------- Page: 4 ----------------------
INTERNATIONAL STANDARD ISO 6401:2022(E)
Plastics — Poly(vinyl chloride) — Determination
of residual vinyl chloride monomer using gas-
chromatographic method
SAFETY PRECAUTIONS — Persons using this document should be familiar with normal laboratory
practice, if applicable. This document does not purport to address all of the safety concerns, if
any, associated with its use. It is the responsibility of the user to establish appropriate safety
and health practices and to determine applicability of any regulatory requirements.
1 Scope
This document specifies a method for the determination of vinyl chloride monomer in homopolymer
and copolymer resins of vinyl chloride and compounded materials. The method is based on sample
dissolution and headspace gas chromatography. Concentrations of vinyl chloride in the range 0,1 mg/
kg to 3,0 mg/kg can be determined.
2 Normative references
The following documents are referred to in the text in such a way that some or all of their content
constitutes requirements of this document. For dated references, only the edition cited applies. For
undated references, the latest edition of the referenced document (including any amendments) applies.
ISO 472, Plastics — Vocabulary
3 Terms and definitions
For the purposes of this document, the terms and definitions given in ISO 472 apply.
ISO and IEC maintain terminology databases for use in standardization at the following addresses:
— ISO Online browsing platform: available at https:// www .iso .org/ obp
— IEC Electropedia: available at https:// www .electropedia .org/
4 Principle
The level of vinyl chloride monomer is determined by headspace gas chromatography of the polymer
test s
...