oSIST prEN ISO 20714:2021

E-liquid - Determination of nicotine, propylene glycol and glycerol in liquids used in electronic nicotine delivery devices - Gas chromatographic method (ISO 20714:2019)

This document specifies an analytical method to quantify the nicotine, propylene glycol and glycerol content in e-liquids by gas chromatography.

E-Liquids - Bestimmung von Nikotin, Propylenglycol und Glycerin in Flüssigkeiten, die in elektronischen Nikotinabgabegeräten verwendet werden - Gaschromatographisches Verfahren (ISO 20714:2019)

Dieses Dokument legt ein Analyseverfahren zur Quantifizierung des Nikotin-, Propylenglykol- und Glyceringehalts in E-Liquids durch Gaschromatographie fest.

E-liquide - Détermination de la teneur en nicotine, propylène glycol et glycérol dans les liquides utilisés avec les systèmes électroniques de délivrance de nicotine - Méthode par chromatographie en phase gazeuse (ISO 20714:2019)

E-tekočine - Ugotavljanje deleža nikotina, propilenglikola in glicerola v tekočinah, ki se uporabljajo v elektronskih napravah za dovajanje nikotina (ISO 20714:2019)

General Information

• Status: Not Published
• Public Enquiry End Date: 31-Oct-2021
• ICS: 65.160 - Tobacco, tobacco products and related equipment
• Technical Committee: I13 - Imaginarni 13
• Current Stage: 4020 - Public enquire (PE) (Adopted Project)
• Start Date: 19-Aug-2021
• Due Date: 06-Jan-2022
• Completion Date: 25-Aug-2021
• Ref Project: prEN ISO 20714 - E-liquid - Determination of nicotine, propylene glycol and glycerol in liquids used in electronic nicotine delivery devices - Gas chromatographic method (ISO 20714:2019)

Standards Content (sample)

SLOVENSKI STANDARD
oSIST prEN ISO 20714:2021
01-oktober-2021

E-tekočine - Ugotavljanje deleža nikotina, propilenglikola in glicerola v tekočinah,

ki se uporabljajo v elektronskih napravah za dovajanje nikotina (ISO 20714:2019)

E-liquid - Determination of nicotine, propylene glycol and glycerol in liquids used in

electronic nicotine delivery devices - Gas chromatographic method (ISO 20714:2019)

E-Liquids - Bestimmung von Nikotin, Propylenglycol und Glycerin in Flüssigkeiten, die in

elektronischen Nikotinabgabegeräten verwendet werden - Gaschromatographisches
Verfahren (ISO 20714:2019)

E-liquide - Détermination de la teneur en nicotine, propylène glycol et glycérol dans les

liquides utilisés avec les systèmes électroniques de délivrance de nicotine - Méthode par

chromatographie en phase gazeuse (ISO 20714:2019)
Ta slovenski standard je istoveten z: prEN ISO 20714
ICS:
65.160 Tobak, tobačni izdelki in Tobacco, tobacco products
oprema and related equipment
oSIST prEN ISO 20714:2021 en,fr,de

2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.

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oSIST prEN ISO 20714:2021
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oSIST prEN ISO 20714:2021
INTERNATIONAL ISO
STANDARD 20714
First edition
2019-08
E-liquid — Determination of
nicotine, propylene glycol and
glycerol in liquids used in electronic
nicotine delivery devices — Gas
chromatographic method
E-liquide — Détermination de la teneur en nicotine, propylène
glycol et glycérol dans les liquides utilisés avec les systèmes
électroniques de délivrance de nicotine — Méthode par
chromatographie en phase gazeuse
Reference number
ISO 20714:2019(E)
ISO 2019
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oSIST prEN ISO 20714:2021
ISO 20714:2019(E)
COPYRIGHT PROTECTED DOCUMENT
© ISO 2019

All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may

be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting

on the internet or an intranet, without prior written permission. Permission can be requested from either ISO at the address

below or ISO’s member body in the country of the requester.
ISO copyright office
CP 401 • Ch. de Blandonnet 8
CH-1214 Vernier, Geneva
Phone: [phone]
Fax: [phone]
Email: [e-mail]
Website: www.iso.org
Published in Switzerland
ii © ISO 2019 – All rights reserved
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oSIST prEN ISO 20714:2021
ISO 20714:2019(E)
Contents Page

Foreword ........................................................................................................................................................................................................................................iv

1 Scope ................................................................................................................................................................................................................................. 1

2 Normative references ...................................................................................................................................................................................... 1

3 Terms and definitions ..................................................................................................................................................................................... 1

4 Principle ........................................................................................................................................................................................................................ 1

5 Reagents ........................................................................................................................................................................................................................ 1

6 Apparatus ..................................................................................................................................................................................................................... 2

7 Sampling ........................................................................................................................................................................................................................ 3

8 Procedure..................................................................................................................................................................................................................... 3

8.1 Test portion ................................................................................................................................................................................................ 3

8.2 Setting up the apparatus................................................................................................................................................................. 3

8.3 Calibration of the gas chromatograph ................................................................................................................................ 4

8.4 Determination ......................................................................................................................................................................................... 4

9 Expression of results ........................................................................................................................................................................................ 4

10 Repeatability and reproducibility ...................................................................................................................................................... 4

11 Test report ................................................................................................................................................................................................................... 5

Annex A (informative) Example chromatogram ....................................................................................................................................... 6

Bibliography ................................................................................................................................................................................................................................ 7

© ISO 2019 – All rights reserved iii
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oSIST prEN ISO 20714:2021
ISO 20714:2019(E)
Foreword

ISO (the International Organization for Standardization) is a worldwide federation of national standards

bodies (ISO member bodies). The work of preparing International Standards is normally carried out

through ISO technical committees. Each member body interested in a subject for which a technical

committee has been established has the right to be represented on that committee. International

organizations, governmental and non-governmental, in liaison with ISO, also take part in the work.

ISO collaborates closely with the International Electrotechnical Commission (IEC) on all matters of

electrotechnical standardization.

The procedures used to develop this document and those intended for its further maintenance are

described in the ISO/IEC Directives, Part 1. In particular the different approval criteria needed for the

different types of ISO documents should be noted. This document was drafted in accordance with the

editorial rules of the ISO/IEC Directives, Part 2 (see www .iso .org/directives).

Attention is drawn to the possibility that some of the elements of this document may be the subject of

patent rights. ISO shall not be held responsible for identifying any or all such patent rights. Details of

any patent rights identified during the development of the document will be in the Introduction and/or

on the ISO list of patent declarations received (see www .iso .org/patents).

Any trade name used in this document is information given for the convenience of users and does not

constitute an endorsement.

For an explanation on the voluntary nature of standards, the meaning of ISO specific terms and

expressions related to conformity assessment, as well as information about ISO's adherence to the

World Trade Organization (WTO) principles in the Technical Barriers to Trade (TBT) see the following

URL: www .iso .org/iso/foreword .html.

This document was prepared by Technical Committee ISO/TC 126, Tobacco and tobacco products,

Subcommittee SC 3, Vape and vapour products.

Any feedback or questions on this document should be directed to the user’s national standards body. A

complete listing of these bodies can be found at www .iso .org/members .html.
iv © ISO 2019 – All rights reserved
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oSIST prEN ISO 20714:2021
INTERNATIONAL STANDARD ISO 20714:2019(E)
E-liquid — Determination of nicotine, propylene glycol
and glycerol in liquids used in electronic nicotine delivery
devices — Gas chromatographic method
1 Scope

This document specifies an analytical method to quantify the nicotine, propylene glycol and glycerol

content in e-liquids by gas chromatography.
2 Normative references
There are no normative references in this document.
3 Terms and definitions
For the purposes of this document, the following terms and definitions apply.

ISO and IEC maintain terminological databases for use in standardization at the following addresses:

— ISO Online browsing platform: available at https: //www .iso .org/obp
— IEC Electropedia: available at http: //www .electropedia .org/
3.1
e-liquid

liquid or gel consumable which may or may not contain nicotine intended for transformation into an

aerosol and then inhaled with an electronic nicotine delivery device (3.2)
3.2
electronic nicotine delivery device
device used to transform an e-liquid (3.1) into an inhalable aerosol
4 Principle

The e-liquid sample is diluted with a solution of isopropanol containing internal standard(s). The

nicotine, propylene glycol and glycerol content of the diluted sample is analysed by capillary gas

chromatography with flame ionization detection (GC-FID) and quantified by using an internal standard.

5 Reagents
Use only reagents of recognized analytical grade.
5.1 Carrier gas:
...