ASTM E2169-17

Standard Practice for Selecting Antimicrobial Pesticides for Use in Water-Miscible Metalworking Fluids

SIGNIFICANCE AND USE
5.1 This practice summarizes the steps in the antimicrobial pesticide selection process, reviewing technical and regulatory considerations inherent in the process. It complements and amplifies information provided in Practice E1497.  
5.1.1 Steps in the antimicrobial selection process include: needs identification, use strategy selection, efficacy testing, chemical compatibility testing, regulatory consideration review, handling, and disposal issue review.  
5.2 This practice provides stakeholders in the microbicide selection process an overview of its complexities, including the process of obtaining pesticide registration from cognizant governing bodies.  
5.3 Personnel responsible for antimicrobial pesticide selection will be able to use this practice as a roadmap through the process.  
5.4 Personnel responsible for industrial hygiene, product or plant management will gain insight to the tradeoffs attendant with antimicrobial use and selection.
SCOPE
1.1 This practice provides recommendations for selecting antimicrobial pesticides (microbicides) for use in water-miscible metalworking fluids (MWF). It presents information regarding regulatory requirements, as well as technical factors including target microbes, efficacy, and chemical compatibility.  
1.2 This guide is not an encyclopedic compilation of all the concepts and terminology uses by chemists, microbiologists, toxicologists, formulators, plant engineers, and regulatory affairs specialists involved in antimicrobial pesticide selection and application. Instead, it provides a general understanding of the selection process and its supporting considerations.  
1.3 The values in SI units are to be regarded as the standard.  
1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

General Information

• Status: Historical
• Publication Date: 28-Feb-2017
• ICS: 65.100.01 - Pesticides and other agrochemicals in general
• Technical Committee: E34 - Occupational Health and Safety
• Drafting Committee: E34.50 - Health and Safety Standards for Metal Working Fluids

Standards Content (Sample)

NOTICE: This standard has either been superseded and replaced by a new version or withdrawn.
Contact ASTM International (www.astm.org) for the latest information
Designation: E2169 − 17 An American National Standard
Standard Practice for
Selecting Antimicrobial Pesticides for Use in Water-Miscible
1
Metalworking Fluids
This standard is issued under the fixed designation E2169; the number immediately following the designation indicates the year of
original adoption or, in the case of revision, the year of last revision. A number in parentheses indicates the year of last reapproval. A
superscript epsilon (´) indicates an editorial change since the last revision or reapproval.
1. Scope from Waters Analyzed by Plating Methods
E686 Method for Evaluation of Antimicrobial Agents in
1.1 This practice provides recommendations for selecting
3
Aqueous Metal Working Fluids (Withdrawn 2004)
antimicrobial pesticides (microbicides) for use in water-
E1302 Guide for Acute Animal Toxicity Testing of Water-
miscible metalworking fluids (MWF). It presents information
Miscible Metalworking Fluids
regarding regulatory requirements, as well as technical factors
E1326 Guide for Evaluating Non-culture Microbiological
includingtargetmicrobes,efficacy,andchemicalcompatibility.
Tests
1.2 This guide is not an encyclopedic compilation of all the
E1497 Practice for Selection and Safe Use of Water-
concepts and terminology uses by chemists, microbiologists,
Miscible and Straight Oil Metal Removal Fluids
toxicologists, formulators, plant engineers, and regulatory
E2144 Practice for Personal Sampling and Analysis of En-
affairs specialists involved in antimicrobial pesticide selection
dotoxin in Metalworking Fluid Aerosols in Workplace
and application. Instead, it provides a general understanding of
Atmospheres
the selection process and its supporting considerations.
2.2 Government Standards:
4
1.3 The values in SI units are to be regarded as the standard.
29 CFR 1910 Occupational Safety and Health Standards
1.4 This standard does not purport to address all of the 40 CFR 152 Pesticide Registration and Classification Proce-
4
dures
safety concerns, if any, associated with its use. It is the
responsibility of the user of this standard to establish appro- 40 CFR 158 Pesticide Programs Data Requirements for
4
Registration
priate safety and health practices and determine the applica-
bility of regulatory limitations prior to use. 49 CFR 100-180 Research and Special Programs
4
Administration, Department of Transportation
2. Referenced Documents
PR Notice 2000-1 Applicability of the Treated Articles
2
Exemption to Antimicrobial Pesticides
2.1 ASTM Standards:
Directive 98/8/EC of the European Parliament and of the
D1067 Test Methods for Acidity or Alkalinity of Water
Council of 16 February 1998 concerning the placing of
D1293 Test Methods for pH of Water
biocidal products on the market
D3519 Test Method for Foam in Aqueous Media (Blender
3
Test) (Withdrawn 2013)
3. Terminology
D3946 Test Method for Evaluating the Bacteria Resistance
of Water-Dilutable Metalworking Fluids (Withdrawn 3.1 active ingredient (a.i.), n—the chemical component or
3
2004) components of an antimicrobial pesticide that provides its
3
D4478 Test Methods for Oxygen Uptake (Withdrawn 1994) microbicidal performance.
D5465 Practices for Determining Microbial Colony Counts
3.2 activity spectrum, n—variety or range of microbes
against which an antimicrobial pesticide is effective.
3.3 antimicrobial pesticide, n—chemical additive, regis-
1
This practice is under the jurisdiction of ASTM Committee E34 on Occupa-
tered under 40 CFR 152, for use to inhibit growth,
tional Health and Safety and is the direct responsibility of Subcommittee E34.50 on
Health and Safety Standards for Metal Working Fluids.
proliferation, or both of microorganisms.
Current edition approved March 1, 2017. Published March 2017. Originally
3.3.1 Discussion—Antimicrobial pesticides are registered
approved in 2001. Last previous edition approved in 2012 as E2169 – 12. DOI:
for one or more end-use applications, or sites, for use within an
10.1520/E2169-17.
2
approved dose range.
For referenced ASTM standards, visit the ASTM website, www.astm.org, or
contact ASTM Customer Service at [e-mail]. For Annual Book of ASTM
Standards volume information, refer to the standard’s Document Summary page on
the ASTM website.
3 4
The last approved version of this historical standard is referenced on Code of Federal regulations available form United States Government Printing
www.astm.org. Office, Washington, DC.
Copyright © ASTM International, 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959. United States
1

---------------------- Page: 1 ----------------------
E2169 − 17
3.4 bactericide, n—antimicrobial pesticide specifically or 3.16.1 Discussion—The LD is the term used in toxicology
50
primarily effective against bacteria. defining the dose that kills fifty percent of the test population.
3.17 microbici
...

This document is not an ASTM standard and is intended only to provide the user of an ASTM standard an indication of what changes have been made to the previous version. Because
it may not be technically possible to adequately depict all changes accurately, ASTM recommends that users consult prior editions as appropriate. In all cases only the current version
of the standard as published by ASTM is to be considered the official document.
Designation: E2169 − 12 E2169 − 17 An American National Standard
Standard Practice for
Selecting Antimicrobial Pesticides for Use in Water-Miscible
1
Metalworking Fluids
This standard is issued under the fixed designation E2169; the number immediately following the designation indicates the year of
original adoption or, in the case of revision, the year of last revision. A number in parentheses indicates the year of last reapproval. A
superscript epsilon (´) indicates an editorial change since the last revision or reapproval.
1. Scope
1.1 This practice provides recommendations for selecting antimicrobial pesticides (microbicides) for use in water-miscible
metalworking fluids (MWF). It presents information regarding regulatory requirements, as well as technical factors including target
microbes, efficacy, and chemical compatibility.
1.2 This guide is not an encyclopedic compilation of all the concepts and terminology uses by chemists, microbiologists,
toxicologists, formulators, plant engineers, and regulatory affairs specialists involved in antimicrobial pesticide selection and
application. Instead, it provides a general understanding of the selection process and its supporting considerations.
1.3 The values in SI units are to be regarded as the standard.
1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility
of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory
limitations prior to use.
2. Referenced Documents
2
2.1 ASTM Standards:
D1067 Test Methods for Acidity or Alkalinity of Water
D1293 Test Methods for pH of Water
3
D3519 Test Method for Foam in Aqueous Media (Blender Test) (Withdrawn 2013)
3
D3946 Test Method for Evaluating the Bacteria Resistance of Water-Dilutable Metalworking Fluids (Withdrawn 2004)
3
D4478 Test Methods for Oxygen Uptake (Withdrawn 1994)
D5465 Practices for Determining Microbial Colony Counts from Waters Analyzed by Plating Methods
3
E686 Method for Evaluation of Antimicrobial Agents in Aqueous Metal Working Fluids (Withdrawn 2004)
E1302 Guide for Acute Animal Toxicity Testing of Water-Miscible Metalworking Fluids
E1326 Guide for Evaluating Non-culture Microbiological Tests
E1497 Practice for Selection and Safe Use of Water-Miscible and Straight Oil Metal Removal Fluids
E2144 Practice for Personal Sampling and Analysis of Endotoxin in Metalworking Fluid Aerosols in Workplace Atmospheres
2.2 Government Standards:
4
29 CFR 1910 Occupational Safety and Health Standards
4
40 CFR 152 Pesticide Registration and Classification Procedures
4
40 CFR 158 Pesticide Programs Data Requirements for Registration
4
49 CFR 100-180 Research and Special Programs Administration, Department of Transportation
PR Notice 2000-1 Applicability of the Treated Articles Exemption to Antimicrobial Pesticides
Directive 98/8/EC of the European Parliament and of the Council of 16 February 1998 concerning the placing of biocidal
products on the market
1
This practice is under the jurisdiction of ASTM Committee E34 on Occupational Health and Safety and is the direct responsibility of Subcommittee E34.50 on Health
and Safety Standards for Metal Working Fluids.
Current edition approved Nov. 1, 2012March 1, 2017. Published November 2012March 2017. Originally approved in 2001. Last previous edition approved in 20072012
as E2169 - 01 (2007).E2169 – 12. DOI: 10.1520/E2169-12.10.1520/E2169-17.
2
For referenced ASTM standards, visit the ASTM website, www.astm.org, or contact ASTM Customer Service at [e-mail]. For Annual Book of ASTM Standards
volume information, refer to the standard’s Document Summary page on the ASTM website.
3
The last approved version of this historical standard is referenced on www.astm.org.
4
Code of Federal regulations available form United States Government Printing Office, Washington, DC.
Copyright © ASTM International, 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959. United States
1

---------------------- Page: 1 ----------------------
E2169 − 17
3. Terminology
3.1 active ingredient (a.i.), n—the chemical component or components of an antimicrobial pesticide that provides its
microbicidal performance.
3.2 activity spectrum, n—variety or range of microbes against which an antimicrobial pesticide is effective.
3.3 antimicrobial pesticide, n—chemical additive, registered under 40 CFR 152, for use to inhibit growth, proliferation, or both
of microorganisms.
3.3.1 Discussion—
Antimicrobial p
...