CEN ISO/TS 24672:2024
(Main)Nanotechnologies - Guidance on the measurement of nanoparticle number concentration (ISO/TS 24672:2023)
Nanotechnologies - Guidance on the measurement of nanoparticle number concentration (ISO/TS 24672:2023)
This document provides an overview of the methods used to determine the nanoparticle number concentration in liquid dispersions and aerosols. The methods described are the ensemble measurement techniques of differential centrifugal sedimentation (DCS), multi-angle dynamic light scattering (MDLS), small-angle X-ray scattering (SAXS) and ultraviolet-visible spectroscopy (UV-vis) and the particle counting methods of particle tracking analysis (PTA), resistive pulse sensing (RPS), single particle inductively coupled plasma mass spectrometry (spICP-MS), condensation particle counter (CPC), and differential mobility analysing system (DMAS). This document provides information on the use of each technique, along with considerations on sample preparation, advantages and limitations.
Nanotechnologien - Leitfaden für die Messung der Konzentration von Nanopartikeln (ISO/TS 24672:2023)
Nanotechnologies - Conseils pour la mesure de la concentration en nombre de nanoparticules (ISO/TS 24672:2023)
Nanotehnologije - Navodilo za merjenje številčnosti koncentracije nanodelcev (ISO/TS 24672:2023)
General Information
Standards Content (Sample)
SLOVENSKI STANDARD
01-julij-2024
Nanotehnologije - Navodilo za merjenje številčnosti koncentracije nanodelcev
(ISO/TS 24672:2023)
Nanotechnologies - Guidance on the measurement of nanoparticle number
concentration (ISO/TS 24672:2023)
Nanotechnologies - Conseils pour la mesure de la concentration en nombre de
nanoparticules (ISO/TS 24672:2023)
Ta slovenski standard je istoveten z: FprCEN ISO/TS 24672
ICS:
07.120 Nanotehnologije Nanotechnologies
2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.
TECHNICAL ISO/TS
SPECIFICATION 24672
First edition
2023-11
Nanotechnologies — Guidance on the
measurement of nanoparticle number
concentration
Nanotechnologies — Conseils pour la mesure de la concentration en
nombre de nanoparticules
Reference number
ISO/TS 24672:2023(E)
ISO/TS 24672:2023(E)
© ISO 2023
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may
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Published in Switzerland
ii
ISO/TS 24672:2023(E)
Contents Page
Foreword .v
Introduction . vi
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Abbreviated terms . 4
5 Overview . 5
5.1 General . 5
5.2 Comparison of different techniques . 5
5.3 Considerations when selecting a technique . 8
5.3.1 General . 8
5.3.2 Type of particles. 8
5.3.3 Number concentration range . 9
5.3.4 Accuracy and precision . 9
5.3.5 Other factors . 10
5.4 Unit for nanoparticle number concentration . 10
6 Ensemble techniques . .11
6.1 Differential centrifugal sedimentation . 11
6.1.1 General . 11
6.1.2 Sample specifications .12
6.1.3 Technical aspects .12
6.1.4 Sources of uncertainty and challenges . 14
6.1.5 Outlook .15
6.2 Multi-angle dynamic light scattering . 15
6.2.1 General .15
6.2.2 Sample specifications . .15
6.2.3 Technical aspects . 16
6.2.4 Sources of uncertainty and challenges . 17
6.2.5 Outlook . 17
6.3 Small-angle X-ray scattering . 17
6.3.1 General . 17
6.3.2 Sample specifications . 18
6.3.3 Technical aspects . 18
6.3.4 Sources of uncertainty and challenges . 20
6.3.5 Outlook . 20
6.4 Ultraviolet-visible spectroscopy . 20
6.4.1 General .20
6.4.2 Sample specifications . . 21
6.4.3 Technical aspects . 21
6.4.4 Sources of uncertainty and challenges . 22
6.4.5 Outlook .23
7 Particle counting techniques .23
7.1 Particle tracking analysis .23
7.1.1 General .23
7.1.2 Sample specifications . .23
7.1.3 Technical aspects . 24
7.1.4 Sources of uncertainty and challenges . 24
7.1.5 Outlook . 25
7.2 Resistive pulse sensing . 25
7.2.1 General . 25
7.2.2 Sample specifications . 26
7.2.3 Technical aspects . 27
iii
ISO/TS 24672:2023(E)
7.2.4 Sources of uncertainty and challenges .28
7.2.5 Outlook .28
7.3 Single particle inductively coupled plasma mass spectrometry .28
7.3.1 General .28
7.3.2 Sample specifications .29
7.3.3 Technical aspects .29
7.3.4 Sources of uncertainty and challenges . 33
7.3.5 Outlook . 33
7.4 Condensation particle counter and differential mobility analysing system .34
7.4.1 General .34
7.4.2 Sample specifications .34
7.4.3 Technical aspects . 35
7.4.4 Sources of uncertainty and challenges . 37
7.4.5 Outlook .38
Annex A (informative) Summary of VAMAS international interlaboratory studies .40
Annex B (informative) General guidance on sample preparation for suspensions containing
nanoparticles .43
Bibliography .
...
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