ISO 23193:2020
(Main)Traditional Chinese medicine — Lycium barbarum and Lycium chinense fruit
Traditional Chinese medicine — Lycium barbarum and Lycium chinense fruit
This document specifies the minimum requirements and test methods for Lycium barbarum and Lycium chinense fruit, which is derived from the plant of Lycium barbarum L. or Lycium chinense Mill. It is applicable to Lycium barbarum and Lycium chinense fruit that is sold and used as herbal raw materials in the international trade, including unprocessed and traditionally processed materials.
Médecine traditionnelle chinoise — Baie de goji (baie de Lycium barbarum et de Lycium chinense)
General Information
Standards Content (Sample)
INTERNATIONAL ISO
STANDARD 23193
First edition
2020-08
Traditional Chinese medicine — Lycium
barbarum and Lycium chinense fruit
Médecine traditionnelle chinoise — Baie de goji (baie de Lycium
barbarum et de Lycium chinense)
Reference number
©
ISO 2020
© ISO 2020
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ii © ISO 2020 – All rights reserved
Contents Page
Foreword .v
Introduction .vi
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Descriptions . 2
5 Requirements . 4
5.1 Morphological features . 4
5.1.1 Appearance . 4
5.1.2 Colour . 4
5.1.3 Dimensions . 4
5.1.4 Fracture . 4
5.1.5 Odour . 4
5.2 Microscopic characteristics . 4
5.3 Moisture . 5
5.4 Total ash . 5
5.5 Acid-insoluble ash . 5
5.6 Water-soluble extractives . 5
5.7 Thin-layer chromatogram (TLC) identification . 6
5.8 Content of polysaccharide . 6
5.9 Content of marker compound . 6
5.10 Heavy metals . 6
5.11 Pesticide residues . 6
5.12 Sulfur dioxide residues . 6
6 Sampling . 6
7 Test methods . 7
7.1 Macroscopic identification . 7
7.2 Determination of moisture content . 7
7.3 Determination of total ash content. 7
7.4 Determination of acid-insoluble ash content . 7
7.5 Determination of water-solution extractives content . 7
7.6 TLC identification . 7
7.7 Determination of polysaccharide content . 7
7.8 Determination of marker compound content . 7
7.9 Determination of heavy metals contents . 7
7.10 Determination of pesticide residues contents . 7
7.11 Determination of sulfur dioxide residues contents . 8
8 Test report . 8
9 Packaging, storage and transportation . 8
10 Marking and labelling . 8
Annex A (informative) Determination of water-soluble extractives . 9
Annex B (informative) TLC identification .10
Annex C (informative) Determination of polysaccharide content .11
Annex D (informative) Determination of betaine content .13
Annex E (informative) Reference values of national and regional limits of moisture,
total ash, water-soluble extractives, polysaccharides, betaine contents in Lycium
barbarum and Lycium chinense fruit .16
Annex F (informative) Reference information and methods for differentiating Lycium
barbarum L. and Lycium chinense Mill.18
Bibliography .19
iv © ISO 2020 – All rights reserved
Foreword
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This document was prepared by Technical Committee ISO/TC 249, Traditional Chinese medicine.
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Introduction
Lycium barbarum and Lycium chinense fruit, commonly called Lycium fruit or Lycii Fructus, is the dried
fruit of Lycium barbarum Linné or Lycium chinense Mill. (Fam. Solanaceae). Lycium fruit was firstly
recorded in the book ‘Divine Farmer’s Classic of Materia Medica’, and it has a long history in China, Korea,
Japan and other Southeast Asian nations, where it is used to nourish the liver and kidneys and replenish
essence to improve vision. Clinically, owing to its medicinal properties, it plays an important role in the
treatment of diseases such as immune suppression, cancer and diabetic retinopathy.
Additionally, Lycium barbarum and Lycium chinense fruit, with its sweet taste and warming property,
is widely used in functional food and cosmetics. Lycium fruit and its finished products also have a
very high reputation worldwide for their effectiveness, and account for a large market share in the
international trade of Chinese herbal medicines.
Lycium barbarum and Lycium chinense fruit is widely cultivated in the northwest of China, Korea and
Canada, among other places. However, the quality of Lycium fruit provided from different areas or by
different cultivators is quite different. In addition, though Lycium barbarum and Lycium chinense fruit
has been recorded in several pharmacopeia and standards, specifications and quality requirements
in these standards vary. Thus, there is a clear and urgent need to develop an international standard
for harmonizing the existing standards, as well as ensuring the safety and effectiveness of Lycium
barbarum and Lycium chinense fruit.
As national implementation may differ, national standards bodies are invited to modify the values
given in 5.3, 5.4, 5.5, 5.6, 5.8 and Clause 9 in their national standards. Examples of national and regional
values are given in Annex E.
vi © ISO 2020 – All rights reserved
INTERNATIONAL STANDARD ISO 23193:2020(E)
Traditional Chinese medicin
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