ASTM E1093-91(2012)

Standard Specification for Glass Prothrombin Pipet, Disposable

ABSTRACT
This specification covers the physical requirements and corresponding test methods for disposable glass Prothrombin pipets suitable for use in micro techniques for estimating Prothrombin time. The pipet shall be made of Type 1, Class B borosilicate glass, or Type 2 soda lime glass. The physical properties to which the pipets should adhere to are those for design, dimensions, capacity (accuracy and coefficient of variation), graduation lines, pipet nomenclature, blow-out delivery, color coding, marking permanency, and lot control.
SCOPE
1.1 This specification covers a glass disposable Prothrombin pipet suitable for use in micro techniques for estimation of Prothrombin time.  
1.2 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.  
1.3 This precautionary statement pertains only to the test method portion, Section 8, of this specification. This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

General Information

• Status: Historical
• Publication Date: 31-Oct-2012
• ICS: 11.100.99 - Other standards related to laboratory medicine
• Technical Committee: E41 - Laboratory Apparatus
• Drafting Committee: E41.01 - Laboratory Ware and Supplies

Relations

• Replaces: ASTM E1093-91(2005) - Standard Specification for Glass Prothrombin Pipet, Disposable
• Effective Date: 01-Nov-2012
• Replaced By: ASTM E1093-91(2019) - Standard Specification for Glass Prothrombin Pipet, Disposable
• Effective Date: 01-Jan-2019

Standards Content (Sample)

NOTICE: This standard has either been superseded and replaced by a new version or withdrawn.
Contact ASTM International (www.astm.org) for the latest information
Designation:E1093 −91 (Reapproved 2012)
Standard Specification for
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Glass Prothrombin Pipet, Disposable
This standard is issued under the fixed designation E1093; the number immediately following the designation indicates the year of
original adoption or, in the case of revision, the year of last revision. A number in parentheses indicates the year of last reapproval. A
superscript epsilon (´) indicates an editorial change since the last revision or reapproval.
1. Scope 4. Classification
1.1 ThisspecificationcoversaglassdisposableProthrombin 4.1 This specification covers only one glass pipet as illus-
pipet suitable for use in micro techniques for estimation of trated in Fig. X1.1.
Prothrombin time.
5. Materials and Manufacture
1.2 The values stated in SI units are to be regarded as
5.1 The pipet shall be made of borosilicate glass, Type 1;
standard. No other units of measurement are included in this
Class B, or soda lime glass, Type 2, in accordance with
standard.
Specification E438.
1.3 This precautionary statement pertains only to the test
method portion, Section 8, of this specification.This standard
6. Physical Properties
does not purport to address all of the safety concerns, if any,
6.1 Design—The Prothrombin pipet shall be made of one
associated with its use. It is the responsibility of the user of this
piececonstructionglasstubingthatisstraightandwithuniform
standard to establish appropriate safety and health practices
bore and lightly firepolished on both ends. The pipet shall be
and determine the applicability of regulatory limitations prior
made to the dimensions as specified in Fig. X1.1.
to use.
6.2 Dimensions—The pipet shall be made of tubing with a
2. Referenced Documents
minimum outside diameter (o.d.) of 2.3 mm with an inside
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diameter (i.d.) of 1.7 mm. The uniformity of the bore shall be
2.1 ASTM Standards:
60.05 mm throughout the straight portion of the pipet. The
E438 Specification for Glasses in Laboratory Apparatus
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pipet shall be a minimum of 160 mm long.
2.2 ISO Standard:
1769 Laboratory Glassware—Pipettes—Color Coding
6.3 Capacity—The pipet shall be calibrated “to deliver”
(T.D.) 0.1 and 0.2 mLat 20°C. Marking shall be as specified in
3. Terminology
6.5.
3.1 Definitions of Terms Specific to This Standard: 6.3.1 Accuracy (see 3.1.1)—The accuracy from stated vol-
3.1.1 accuracy—the expected distribution of mean volumes ume shall be 62.0 % for the 0.1 and 0.2-mLcapacity and shall
around the stated volume. be determined as specified in 8.1.
6.3.2 Coeffıcient of Variation (see 3.1.2)—The coefficient of
3.1.2 coeffıcient of variation—the expected distribution of
variation from stated volume for the 0.1 and 0.2-mL capacity
individual volumes around the mean volume.
shall not exceed 2.0 % and shall be determined as specified in
3.1.3 disposable—Prothrombin pipets which are intended to
8.1.
be used once only and then discarded.
6.4 Graduation Lines—The pipet shall be calibrated and
NOTE 1—Such pipets will only be expected to provide their specified
marked with graduation lines at 0.1 and 0.2 mLfrom the tip of
performance during the original operation.
the pipet.The graduation lines shall be 0.3 6 0.1 mm and shall
completely encircle the tube.
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This specification is under the jurisdiction of ASTM Committee E41 on
6.5 Pipet Nomenclature—The pipet shall be marked with
Laboratory Apparatus and is the direct responsibility of Subcommittee E41.01 on
0.1 and 0.2-mL markings slightly above the graduation lines.
Apparatus.
ThepipetmaybemarkedwiththeinscriptionT.D.20°C,orthe
Current edition approved Nov. 1, 2012. Published November 2012. Originally
approved in 1986. Last previous edition approved in 2005 as E1093 – 91 (2005).
manufacturer’s or vendor’s name or trademark, or both.
DOI: 10.1520/E1093-91R12.
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6.6 Blow-out Delivery—The Prothrombin pipet is designed
For referenced ASTM standards, visit the ASTM website, www.astm.org, or
contact ASTM Customer Service at [e-mail]. For Annual Book of ASTM
as a dual delivery system for the determinations of coagulation
Standards volume information, refer to the standard’s Document Summary page on
assays.Whenutilizingthe0.2mLcalibrationline,thetipofthe
the ASTM website.
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pipet should contact the wall of the receiving vessel and allow
Available from ISO, 1 Rue de Varembe, Case Postal 56, Crt 1221, Geneva 20,
Switzerland. the pipet to drain freely. The remaining quantity of liquid is to
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E1093−91 (2012)
be blown out into the center of the receiving vessel. When where:
utilizing the 0.1 mL calibration line the contents are to be
W = apparent mass of liquid (water), weighed in air, and
vigorously blown out into the center of the receiv
...