prEN ISO 7012-3
(Main)Paints and varnishes - Determination of preservatives in water-dilutable coating materials - Part 3: Determination of in-can isothiazolinones with LC/UV and LC-MS-MS (ISO/DIS 7012-3:2024)
Paints and varnishes - Determination of preservatives in water-dilutable coating materials - Part 3: Determination of in-can isothiazolinones with LC/UV and LC-MS-MS (ISO/DIS 7012-3:2024)
This document specifies the apparatus and analytical method for determining the content of in-can isothiazolinone preservatives in water-dilutable coating materials or related products.
Note The document is also applicable for polymer dispersions.
Beschichtungsstoffe - Bestimmung von Konservierungsmitteln in wasserverdünnbaren Beschichtungsstoffen - Teil 3: Bestimmung von Isothiazolinonen im Gebinde mit LC-UV und LC‑MS‑MS (ISO/DIS 7012‑3:2024)
Peintures et vernis - Dosage des agents de préservation dans les produits de peinture diluables à l’eau - Partie 3: Dosage des isothiazolinones en pot par CL-UV et CL-SM (ISO/DIS 7012-3:2024)
Barve in laki - Določanje konzervansov v premazih, topnih v vodi - 3. del: Določanje izotiazolinonov v pločevinki/posodi s tekočinsko kromatografijo LC/UV in LC-MS-MS (ISO/DIS 7012-3:2024)
General Information
Standards Content (Sample)
SLOVENSKI STANDARD
01-maj-2024
Barve in laki - Določanje konzervansov v premazih, topnih v vodi - 3. del:
Določanje izotiazolinonov v pločevinki/posodi s tekočinsko kromatografijo LC/UV
in LC-MS-MS (ISO/DIS 7012-3:2024)
Paints and varnishes - Determination of preservatives in water-dilutable coating
materials - Part 3: Determination of in-can isothiazolinones with LC/UV and LC-MS-MS
(ISO/DIS 7012-3:2024)
Beschichtungsstoffe - Bestimmung von Konservierungsmitteln in wasserverdünnbaren
Beschichtungsstoffen - Teil 3: Bestimmung von Isothiazolinonen im Gebinde mit LC-UV
und LC‑MS‑MS (ISO/DIS 7012-3:2024)
Peintures et vernis - Dosage des agents de préservation dans les produits de peinture
diluables à l’eau - Partie 3: Dosage des isothiazolinones en pot par CL-UV et CL-SM
(ISO/DIS 7012-3:2024)
Ta slovenski standard je istoveten z: prEN ISO 7012-3
ICS:
87.040 Barve in laki Paints and varnishes
2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.
DRAFT
International
Standard
ISO/DIS 7012-3
ISO/TC 35/SC 16
Paints and varnishes —
Secretariat: DIN
Determination of preservatives in
Voting begins on:
water-dilutable coating materials —
2024-03-14
Part 3:
Voting terminates on:
2024-06-06
Determination of in-can
isothiazolinones with LC-UV and LC-
MS
ICS: 87.040
THIS DOCUMENT IS A DRAFT CIRCULATED
FOR COMMENTS AND APPROVAL. IT
IS THEREFORE SUBJECT TO CHANGE
AND MAY NOT BE REFERRED TO AS AN
INTERNATIONAL STANDARD UNTIL
PUBLISHED AS SUCH.
This document is circulated as received from the committee secretariat.
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Reference number
ISO/DIS 7012-3:2024(en)
DRAFT
ISO/DIS 7012-3:2024(en)
International
Standard
ISO/DIS 7012-3
ISO/TC 35/SC 16
Paints and varnishes —
Secretariat: DIN
Determination of preservatives in
Voting begins on:
water-dilutable coating materials —
Part 3:
Voting terminates on:
Determination of in-can
isothiazolinones with LC-UV and LC-
MS
ICS: 87.040
THIS DOCUMENT IS A DRAFT CIRCULATED
FOR COMMENTS AND APPROVAL. IT
IS THEREFORE SUBJECT TO CHANGE
AND MAY NOT BE REFERRED TO AS AN
INTERNATIONAL STANDARD UNTIL
PUBLISHED AS SUCH.
This document is circulated as received from the committee secretariat.
IN ADDITION TO THEIR EVALUATION AS
BEING ACCEPTABLE FOR INDUSTRIAL,
© ISO 2024
TECHNOLOGICAL, COMMERCIAL AND
USER PURPOSES, DRAFT INTERNATIONAL
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may
STANDARDS MAY ON OCCASION HAVE TO
ISO/CEN PARALLEL PROCESSING
be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting on
BE CONSIDERED IN THE LIGHT OF THEIR
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NOTIFICATION OF ANY RELEVANT PATENT
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Website: www.iso.org
Published in Switzerland Reference number
ISO/DIS 7012-3:2024(en)
ii
ISO/DIS 7012-3:2024(en)
Contents Page
Foreword .iv
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Principle . 2
5 Apparatus . 2
5.1 Equipment for extraction and sample preparation .2
5.2 LC-UV/VIS system . .3
5.3 LC-MS/MS or LC-MS system .3
6 Reagents and materials . 3
7 Sampling . 5
8 Procedure . 5
8.1 LC-UV/VIS method .5
8.1.1 Extraction of LC-UV/VIS .5
8.1.2 Operation conditions of LC-UV/VIS .6
8.1.3 Blank .6
8.1.4 Interferences of LC-UV/VIS .6
8.1.5 Calibration of LC-UV/VIS . . .6
8.1.6 Determination by LC-UV/VIS .7
8.2 LC-MS method .7
8.2.1 Extraction of LC-MS .7
8.2.2 Further dilution . .7
8.2.3 Filtration .7
8.2.4 Operation conditions of LC-MS .7
8.2.5 Blank .8
8.2.6 Interferences of LC-MS .8
8.2.7 Calibration of LC-MS .8
8.2.8 Determination by LC-MS .9
9 Calculation . 9
10 Precision . 9
10.1 General .9
10.2 Repeatability limit r .10
10.3 Reproducibility limit R .10
11 Test report . 10
Annex A (informative) Example of LC conditions .12
Annex B (informative) Example of multiple reaction monitoring LC-MS/MS conditions .15
Annex C (informative) Calculation of preservative content with standard addition for LC-MS
method .18
Annex D (informative) Mechanical method for homogenization and extraction.20
Annex E (informative) Results of the interlaboratory test .21
Bibliography .22
iii
ISO/DIS 7012-3:2024(en)
Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards
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This document was prepared by Technical Committee ISO/TC 35, Paints and varnishes, Subcommittee SC 16,
Chemical analysis.
iv
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