EN IEC 63041-2:2018

Piezoelectric sensors - Part 2: chemical and biochemical Sensors

IEC 63041-2:2017(E) is applicable to piezoelectric chemical sensors mainly used in the field of biological, medical, gas and environmental sciences. It provides users with technical guidelines on biochemical sensors as well as basic knowledge of common chemical sensors.

Piezoelektrische Sensoren - Teil 2: Chemische und biochemische Sensoren

Capteurs piézoélectriques - Partie 2: Capteurs chimiques et biochimiques

L'IEC 63041-2:2017 s'applique aux capteurs chimiques piézoélectriques principalement utilisés dans le domaine biologique, médical, des gaz et des sciences environnementales. Elle donne aux utilisateurs des lignes directrices techniques relatives aux capteurs biochimiques, ainsi que les connaissances concernant les capteurs chimiques communs.

Piezoelektrični senzorji - 2. del: Kemični in biokemični senzorji (IEC 63041-2:2017)

Ta del standarda IEC 63041 velja za piezoelektrične senzorje, ki se običajno uporabljajo na področju biološke, medicinske, plinske in okoljske znanosti. Uporabnikom zagotavlja tehnične smernice o biokemičnih senzorjih kot tudi osnovno znanje glede običajnih kemičnih senzorjih.

General Information

• Status: Published
• Publication Date: 08-Mar-2018
• Withdrawal Date: 16-Jan-2021
• ICS: 31.140 - Piezoelectric devices
• Technical Committee: CLC/SR 49 - Piezoelectric and dielectric devices for frequency control and selection
• Drafting Committee: IEC/TC 49 - IEC_TC_49
• Current Stage: 6060 - Document made available - Publishing
• Start Date: 09-Mar-2018
• Completion Date: 09-Mar-2018
• Ref Project: SIST EN IEC 63041-2:2018 - Piezoelectric Sensors - Part 2: Chemical and Biochemical Sensors (IEC 63041-2:2017)

Relations

• Revised: FprEN IEC 63041-2:2025 - Piezoelectric sensors - Part 2: Chemical and biochemical sensors
• Effective Date: 12-Nov-2024

Overview

EN IEC 63041-2:2018 (IEC 63041-2:2017) provides technical guidelines for piezoelectric chemical and biochemical sensors used in biological, medical, gas and environmental sciences. It is part of the IEC 63041 series on piezoelectric sensors and focuses on sensor element concepts, specification points, measurement principles and practical guidance for users of BAW (bulk acoustic wave) and SAW (surface acoustic wave) sensor technologies.

Key topics and technical requirements

• Sensor types and definitions: clear distinction between piezoelectric chemical sensor elements (mainly gas-phase detection) and piezoelectric biochemical sensor elements (biomolecule detection in aqueous media).
• BAW and SAW element concepts: conceptual diagrams and cell layouts for BAW resonators (including AT-cut QCM) and SAW devices (resonator and delay-line types).
• Layer specifications:
  • Interface layer - mechanical/electrical interface between transducer and recognition chemistry.
  • Sensitive / receptive layer - target recognition material (selectivity, immobilization).
• Non‑specific reactions: guidance on identifying and mitigating nonspecific or unselective responses that affect accuracy.
• Performance improvement: recommendations to enhance sensitivity, selectivity and stability.
• Delivery conditions, quality and reliability: expectations for supplied sensors, documentation, and reliability considerations.
• Test and measurement procedures: standardized approaches for evaluating sensor response, stability and calibration.
• Annex A (informative): chemical reaction principles in sensor cells, reference values, typical formulae for response and calibration approaches for QCM and SAW devices.

Practical applications

EN IEC 63041-2 supports users and developers working with:

• Biomedical diagnostics (biomarker detection, cell monitoring)
• Environmental monitoring (air quality, gas and vapor sensing)
• Industrial safety (toxic gas, smoke and odor detection)
• Laboratory instrumentation & lab‑on‑a‑chip (biochemical assays using acoustic transducers)
• R&D and product development for sensor manufacturers optimizing recognition layers and measurement protocols

Typical users:

• Sensor designers and manufacturers
• Test and calibration laboratories
• System integrators and instrument suppliers
• Regulatory and procurement bodies evaluating sensor specifications
• Researchers in analytical chemistry, biochemistry and environmental science

Related standards

• EN IEC 63041-1 / IEC 63041-1 - Piezoelectric sensors - Part 1: Generic specifications
• IEC 60027, IEC 60050-561, ISO 80000-1 - terminology, symbols and units referenced by this part

This standard is a practical reference for deploying and specifying piezoelectric chemical and biochemical sensors, helping ensure reliable, reproducible sensor selection, design and testing in biomedical, gas and environmental applications.

Standards Content (Sample)

SLOVENSKI STANDARD
01-maj-2018
3LH]RHOHNWULþQLVHQ]RUMLGHO.HPLþQLLQELRNHPLþQLVHQ]RUML,(&
Piezoelectric Sensors - Part 2: Chemical and Biochemical Sensors (IEC 63041-2:2017)
Ta slovenski standard je istoveten z: EN IEC 63041-2:2018
ICS:
31.140 3LH]RHOHNWULþQHQDSUDYH Piezoelectric devices
2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.

EUROPEAN STANDARD EN IEC 63041-2

NORME EUROPÉENNE
EUROPÄISCHE NORM
March 2018
ICS 31.140
English Version
Piezoelectric sensors - Part 2: chemical and biochemical
sensors
(IEC 63041-2:2017)
Capteurs piézoélectriques - Partie 2: Capteurs chimiques et Piezoelektrische Sensoren - Teil 2: Chemische und
biochimiques biochemische Sensoren
(IEC 63041-2:2017) (IEC 63041-2:2017)
This European Standard was approved by CENELEC on 2018-01-17. CENELEC members are bound to comply with the CEN/CENELEC
Internal Regulations which stipulate the conditions for giving this European Standard the status of a national standard without any alteration.
Up-to-date lists and bibliographical references concerning such national standards may be obtained on application to the CEN-CENELEC
Management Centre or to any CENELEC member.
This European Standard exists in three official versions (English, French, German). A version in any other language made by translation
under the responsibility of a CENELEC member into its own language and notified to the CEN-CENELEC Management Centre has the
same status as the official versions.
CENELEC members are the national electrotechnical committees of Austria, Belgium, Bulgaria, Croatia, Cyprus, the Czech Republic,
Denmark, Estonia, Finland, Former Yugoslav Republic of Macedonia, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia,
Lithuania, Luxembourg, Malta, the Netherlands, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden,
Switzerland, Turkey and the United Kingdom.

European Committee for Electrotechnical Standardization
Comité Européen de Normalisation Electrotechnique
Europäisches Komitee für Elektrotechnische Normung
CEN-CENELEC Management Centre: Rue de la Science 23, B-1040 Brussels
© 2018 CENELEC All rights of exploitation in any form and by any means reserved worldwide for CENELEC Members.
Ref. No. EN IEC 63041-2:2018 E

European foreword
The text of document 49/1221/CDV, future edition 1 of IEC 63041-2, prepared by IEC/TC 49
"Piezoelectric, dielectric and electrostatic devices and associated materials for frequency control,
selection and detection" was submitted to the IEC-CENELEC parallel vote and approved by
CENELEC as EN IEC 63041-2:2018.

The following dates are fixed:
• latest date by which the document has to be (dop) 2018-10-17
implemented at national level by
publication of an identical national
standard or by endorsement
(dow) 2021-01-17
• latest date by which the national
standards conflicting with the
document have to be withdrawn
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. CENELEC shall not be held responsible for identifying any or all such patent rights.

Endorsement notice
The text of the International Standard IEC 63041-2:2017 was approved by CENELEC as a European
Standard without any modification.
In the official version, for Bibliography, the following notes have to be added for the standards indicated:

IEC 60068 (series) NOTE Harmonized as EN 60068 (series).
IEC 60122-1 NOTE Harmonized as EN 60122-1.
IEC 60444-1 NOTE Harmonized as EN 60444-1.
IEC 60444-5 NOTE Harmonized as EN 60444-5.
IEC 60444-9 NOTE Harmonized as EN 60444-9.
IEC 60679 (series) NOTE Harmonized as EN 60679 (series).
IEC 60758:2008 NOTE Harmonized as EN 60758:2009 (not modified).
IEC 60862-1 NOTE Harmonized as EN 60862-1.
IEC 61019-1:2004 NOTE Harmonized as EN 61019-1:2005 (not modified).
IEC 61240:2016 NOTE Harmonized as EN 61240:2016 (not modified).
IEC 61760 (series) NOTE Harmonized as EN 61760 (series).
IEC 61837 (series) NOTE Harmonized as EN 61837 (series).
IEC 62276:2016 NOTE Harmonized as EN 62276:2016 (not modified).
Annex ZA
(normative)
Normative references to international publications
with their corresponding European publications

The following documents are referred to in the text in such a way that some or all of their content
constitutes requirements of this document. For dated references, only the edition cited applies. For
undated references, the latest edition of the referenced document (including any amendments)
applies.
NOTE 1  Where an International Publication has been modified by common modifications, indicated by (mod), the relevant
EN/HD applies.
NOTE 2  Up-to-date information on the latest versions of the European Standards listed in this annex is available here:
www.cenelec.eu.
Publication Year Title EN/HD Year
IEC 60027 series Letter symbols to be used in electrical EN 60027 series
technology - Part 1: General
IEC 60050-561 2014 International electrotechnical vocabulary - - -
Part 561: Piezoelectric, dielectric and
electrostatic devices and associated
materials for frequency control, selection
and detection
IEC 60617 -  Standard data element types with - -
associated classification scheme for
electric components - Part 4: IEC reference
collection fo standard data element types
and component classes
IEC 63041-1 -  Piezoelectric sensors - Part 1: Generic EN IEC 63041-1 -
specifications
ISO 80000-1 2009 Quantities and units - Part 1: General EN ISO 80000-1 2013

IEC 63041-2 ®
Edition 1.0 2017-12
INTERNATIONAL
STANDARD
colour
inside
Piezoelectric sensors –
Part 2: Chemical and biochemical sensors

INTERNATIONAL
ELECTROTECHNICAL
COMMISSION
ICS 31.140 ISBN 978-2-8322-5144-7

– 2 – IEC 63041-2:2017 © IEC 2017
CONTENTS
FOREWORD . 3
1 Scope . 5
2 Normative references . 5
3 Terms and definitions . 5
3.1 General . 5
3.2 Types of chemical and biochemical sensors . 6
4 Specifications . 6
4.1 General . 6
4.2 Conceptual diagram of BAW sensor elements and cells . 6
4.3 Conceptual diagram of SAW sensor elements and cells . 6
4.4 Key points of specifications . 7
4.4.1 General . 7
4.4.2 Interface layer . 7
4.4.3 Sensitive or receptive layer (target recognition material) . 7
4.4.4 Nonspecific and unselective reactions . 8
4.5 Improved sensor performance . 8
4.6 Technical documents . 8
5 Delivery conditions . 8
6 Quality and reliability . 8
7 Test and measurement procedures . 8
Annex A (informative) Chemical reaction in sensor cells . 9
A.1 Reference values before and after reaction . 9
A.2 Typical formulae . 10
A.2.1 General . 10
A.2.2 BAW (AT-cut QCM) . 10
A.2.3 SAW . 11
A.3 Calibration . 14
Bibliography . 15

Figure 1 – Conceptual diagram for chemical and biochemical sensor elements and
cells of BAW resonator type (side view) . 6
Figure 2 – Conceptual diagram for chemical and biochemical sensor elements and
cells of SAW resonator type (side view) . 7
Figure 3 – Conceptual diagram for chemical and biochemical sensor elements and
cells of SAW delay-line type (top view) . 7
Figure 4 – Conceptual diagram for SAW chemical and biochemical sensor elements
and cells with three-layer reaction region on a propagation surface (side view) . 8
Figure A.1 – Frequency-time characteristics . 9
Figure A.2 – Conceptual resonance response of an SAW sensor cell . 10

IEC 63041-2:2017 © IEC 2017 – 3 –
INTERNATIONAL ELECTROTECHNICAL COMMISSION
____________
PIEZOELECTRIC SENSORS –
Part 2: Chemical and biochemical sensors

FOREWORD
1) The International Electrotechnical Commission (IEC) is a worldwide organization for standardization comprising
all national electrotechnical committees (IEC National Committees). The object of IEC is to promote
international co-operation on all questions concerning standardization in the electrical and electronic fields. To
this end and in addition to other activities, IEC publishes International Standards, Technical Specifications,
Technical Reports, Publicly Available Specifications (PAS) and Guides (hereafter referred to as “IEC
Publication(s)”). Their preparation is entrusted to technical committees; any IEC National Committee interested
in the subject dealt with may participate in this preparatory work. International, governmental and non-
governmental organizations liaising with the IEC also participate in this preparation. IEC collaborates closely
with the International Organization for Standardization (ISO) in accordance with conditions determined by
agreement between the two organizations.
2) The formal decisions or agreements of IEC on technical matters express, as nearly as possible, an international
consensus of opinion on the relevant subjects since each technical committee has representation from all
interested IEC National Committees.
3) IEC Publications have the form of recommendations for international use and are accepted by IEC National
Committees in that sense. While all reasonable efforts are made to ensure that the technical content of IEC
Publications is accurate, IEC cannot be held responsible for the way in which they are used or for any
misinterpretation by any end user.
4) In order to promote international uniformity, IEC National Committees undertake to apply IEC Publications
transparently to the maximum extent possible in their national and regional publications. Any divergence
between any IEC Publication and the corresponding national or regional publication shall be clearly indicated in
the latter.
5) IEC itself does not provide any attestation of conformity. Independent certification bodies provide conformity
assessment services and, in some areas, access to IEC marks of conformity. IEC is not responsible for any
services carried out by independent certification bodies.
6) All users should ensure that they have the latest edition of this publication.
7) No liability shall attach to IEC or its directors, employees, servants or agents including individual experts and
members of its technical committees and IEC National Committees for any personal injury, property damage or
other damage of any nature whatsoever, whether direct or indirect, or for costs (including legal fees) and
expenses arising out of the publication, use of, or reliance upon, this IEC Publication or any other IEC
Publications.
8) Attention is drawn to the Normative references cited in this publication. Use of the referenced publications is
indispensable for the correct application of this publication.
9) Attention is drawn to the possibility that some of the elements of this IEC Publication may be the subject of
patent rights. IEC shall not be held responsible for identifying any or all such patent rights.
International Standard IEC 63041-2 has been prepared by IEC technical committee TC 49:
Piezoelectric, dielectric and electrostatic devices and associated materials for frequency
control, selection and detection.
The text of this International Standard is based on the following documents:
CDV Report on voting
49/1221/CDV 49/1250/RVC
Full information on the voting for the approval of this International Standard can be found in
the report on voting indicated in the above table.
This document has been drafted in accordance with the ISO/IEC Directives, Part 2.
A list of all parts in the IEC 63041 series, published under the general title Piezoelectric
sensors, can be found on the IEC website.

– 4 – IEC 63041-2:2017 © IEC 2017
The committee has decided that the contents of this publication will remain unchanged until
the stability date indicated on the IEC website under "http://webstore.iec.ch" in the data
related to the specific publication. At this date, the publication will be
• reconfirmed,
• withdrawn,
• replaced by a revised edition, or
• amended.
A bilingual version of this publication may be issued at a later date.

IMPORTANT – The 'colour inside' logo on the cover page of this publication indicates
that it contains colours which are considered to be useful for the correct
understanding of its contents. Users should therefore print this document using a
colour printer.
IEC 63041-2:2017 © IEC 2017 – 5 –
PIEZOELECTRIC SENSORS –
Part 2: Chemical and biochemical sensors

1 Scope
This part of IEC 63041 is applicable to piezoelectric chemical sensors mainly used in the field
of biological, medical, gas and environmental sciences. It provides users with technical
guidelines on biochemical sensors as well as basic knowledge of common chemical sensors.
2 Normative references
The following documents are referred to in the text in such a way that some or all of their
content constitutes requirements of this document. For dated references, only the edition
cited applies. For undated references, the latest edition of the referenced document (including
any amendments) applies.
IEC 60027 (all parts), Letter symbols to be used in electrical technology
IEC 60050-561-:2014, International Electrotechnical Vocabulary – Part 561: Piezoelectric,
dielectric and electrostatic devices and associated materials for frequency control, selection
and detection
IEC 60617, Graphical symbols for diagrams, available at http://std.iec.ch/iec60617
IEC 63041-1, Piezoelectric sensors – Part 1: Generic specifications
ISO 80000-1:2009, Quantities and units – Part 1: General
3 Terms and definitions
3.1 General
For the purpose of this document, the following terms and definitions apply.
ISO and IEC maintain terminological databases for use in standardization at the following
addresses;
• IEC Electropedia: available at http://www.electropedia.org/
• ISO Online browsing platform: available at http://www.iso.org/obp
Units, letter symbols and terminology shall, wherever possible, be taken from the following
standards: IEC 60027, IEC 60050-561, IEC 60617, IEC 63041-1, and ISO 80000-1.
NOTE 1 In the market of chemical and biochemical sensors, the terms related in fields such as chemistry,
biochemistry, healthcare, etc. are widely used.
NOTE 2 Piezoelectric sensors covered herein are those used for the detection and measurement of either
chemical substance in the gas phase or biological molecules in aqueous media.

– 6 – IEC 63041-2:2017 © IEC 2017
3.2 Types of chemical and biochemical sensors
3.2.1
piezoelectric chemical sensor element
piezoelectric sensor c
...