SIST EN 12884:1999
(Main)Biotechnology - Performance criteria for centrifuges
General Information
- Abstract
This European Standard specifies performance criteria for centrifuges used in biotechnological processes with respect to the potential risks of microorganisms in use for the worker or the environment.
- Status
- Published
- Publication Date
- 30-Nov-1999
- Technical Committee
- BTH - Biotechnology
- Current Stage
- 6060 - National Implementation/Publication (Adopted Project)
- Start Date
- 01-Dec-1999
- Due Date
- 01-Dec-1999
- Completion Date
- 01-Dec-1999
Overview
EN 12884:1999 - published by CEN - is the European standard titled "Biotechnology - Performance criteria for centrifuges". It specifies performance criteria for centrifuges used in biotechnological processes with respect to the potential risks posed by microorganisms to workers and the environment. The standard provides a framework for evaluating centrifuge designs and operation where biological containment and biosafety are critical.
Key topics
The standard focuses on performance criteria related to microbiological risk control. While the full text defines the official requirements, key technical topics typically addressed under this scope include:
- Biological containment and aerosol control to minimise release of microorganisms during operation, loading and unloading.
- Leakage and sealing performance of rotors, lids and sample holders to prevent escape of contaminants.
- Decontamination and cleaning provisions to support safe maintenance and routine sanitation.
- Operational safety and maintenance requirements that affect microbial risk (inspection, balancing, emergency procedures).
- Performance verification and testing to demonstrate that a centrifuge meets the criteria for safe use with biological materials.
- Documentation and labeling for safe use, maintenance instructions and risk information relevant to biotechnology applications.
(These topics reflect the standard’s stated scope - performance criteria for centrifuges used in biotechnological processes - and what laboratories and manufacturers evaluate against such a standard.)
Applications
EN 12884:1999 is directly relevant to:
- Biotech and pharmaceutical laboratories that process microorganisms or biologically active materials.
- Equipment manufacturers and OEMs designing centrifuges intended for biological applications who need to demonstrate containment performance.
- Laboratory safety officers and biosafety committees assessing equipment suitability for specific containment levels.
- Procurement and validation teams selecting and qualifying centrifuges for R&D, production, or clinical laboratories.
- Testing and certification bodies that evaluate centrifuge performance against European safety expectations.
Using this standard helps reduce occupational exposure, support environmental protection, and provide objective criteria for selecting and validating centrifugation equipment in biotechnology.
Related standards
EN 12884:1999 sits alongside other European and international standards covering laboratory equipment safety, biosafety management and equipment validation. Users should consult complementary standards on laboratory safety, biocontainment and equipment testing for a complete compliance and risk-management approach.
Keywords: EN 12884:1999, biotechnology centrifuge standard, centrifuge performance, centrifuge biosafety, CEN standard, biological containment, laboratory equipment standards.
Relations
- Effective Date
- 28-Jan-2026
- Refers
SIST EN 12298:1999 - Biotechnology - Equipment - Guidance on testing procedures for leaktightness - Effective Date
- 28-Jan-2026
- Refers
SIST EN 1672-2:2021 - Food processing machinery - Basic concepts - Part 2: Hygiene requirements - Effective Date
- 28-Jan-2026
- Effective Date
- 28-Jan-2026
- Effective Date
- 28-Jan-2026
- Effective Date
- 28-Jan-2026
- Effective Date
- 28-Jan-2026
- Effective Date
- 28-Jan-2026
- Effective Date
- 28-Jan-2026
- Refers
SIST EN 12297:1999 - Biotechnology - Equipment - Guidance on testing procedures for sterilizability - Effective Date
- 28-Jan-2026
- Refers
SIST EN 12296:1999 - Biotechnology - Equipment - Guidance on testing procedures for cleanability - Effective Date
- 28-Jan-2026
Frequently Asked Questions
SIST EN 12884:1999 is a standard published by the Slovenian Institute for Standardization (SIST). Its full title is "Biotechnology - Performance criteria for centrifuges". This standard covers: This European Standard specifies performance criteria for centrifuges used in biotechnological processes with respect to the potential risks of microorganisms in use for the worker or the environment.
This European Standard specifies performance criteria for centrifuges used in biotechnological processes with respect to the potential risks of microorganisms in use for the worker or the environment.
SIST EN 12884:1999 is classified under the following ICS (International Classification for Standards) categories: 07.080 - Biology. Botany. Zoology. The ICS classification helps identify the subject area and facilitates finding related standards.
SIST EN 12884:1999 has the following relationships with other standards: It is inter standard links to SIST EN ISO 21920-2:2022, SIST EN 12298:1999, SIST EN 1672-2:2021, SIST EN 12460:1999, SIST EN 12690:1999, SIST EN ISO 12100:2011, SIST EN 12547:2015, SIST EN ISO 14123-1:2016, SIST EN ISO 21920-3:2022, SIST EN 12297:1999, SIST EN 12296:1999. Understanding these relationships helps ensure you are using the most current and applicable version of the standard.
SIST EN 12884:1999 is associated with the following European legislation: EU Directives/Regulations: 90/219/EEC, 90/220/EEC, 90/679/EEC; Standardization Mandates: M/BC/CEN/91/19. When a standard is cited in the Official Journal of the European Union, products manufactured in conformity with it benefit from a presumption of conformity with the essential requirements of the corresponding EU directive or regulation.
SIST EN 12884:1999 is available in PDF format for immediate download after purchase. The document can be added to your cart and obtained through the secure checkout process. Digital delivery ensures instant access to the complete standard document.
Standards Content (Sample)
2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.Biotehnologija – Merila za delovaje centrifugBiotechnik - Leistungskriterien für ZentrifugenBiotechnologie - Criteres de performance pour les centrifugeusesBiotechnology - Performance criteria for centrifuges07.080Biologija. Botanika. ZoologijaBiology. Botany. ZoologyICS:Ta slovenski standard je istoveten z:EN 12884:1
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