ISO/TC 146/SC 6/WG 20 - Determination of phthalates

This document specifies a sampling method to determine the quantity of formaldehyde (HCHO) in the air with the range of approximately 1 µg/m3 to 1 mg/m3 in a time-weighted average (TWA) sample, for long-term (1 h to 24 h) and short-term (5 min to 60 min) sampling. This method involves the collection of compounds from air on to adsorbent cartridges coated with 2,4-dinitrophenylhydrazine (DNPH) and subsequent analysis of the hydrazones formed by high performance liquid chromatography (HPLC) with detection by ultraviolet absorption [7] [8]. This document can also be applied for the determination of at least 12 other aromatic as well as saturated and unsaturated aliphatic carbonyl compounds (aldehydes and ketones), with modification, such as: — acetaldehyde; — acetone; — benzaldehyde; — butyraldehyde; — capronaldehyde; — 2,5-dimethylbenzaldehyde; — formaldehyde; — isovaleraldehyde; — propionaldehyde; — m-tolualdehyde; — o-tolualdehyde; — p-tolualdehyde; — valeraldehyde. This document does not apply to longer chained or unsaturated carbonyl compounds such as acrolein. An alternative sampling method using sorbent tubes and analysis by thermal desorption using gas chromatography with mass spectrometry (GC-MS) is given in Annex A.

ISO 16000-33:2017 specifies the sampling and analysis of phthalates in indoor air and describes the sampling and analysis of phthalates in house dust and in solvent wipe samples of surfaces by means of gas chromatography/mass spectrometry. Two alternative sampling and processing methods, whose comparability has been proven in a round robin test, are specified for indoor air[4]. Sampling can take place using sorbent tubes with subsequent thermal desorption and GC-MS analysis. Alternatively, sampling can take on other types of sorbent tubes that are subsequently analysed by solvent extraction with GC-MS. Depending on the sampling method, the compounds dimethyl phthalate to diisoundecylphthalate can be analysed in house dust as described in Annex C[8]. The investigation of house dust samples is only appropriate as a screening method. This investigation only results in indicative values and is not acceptable for a final assessment of a potential need for action. Dimethyl phthalate to diisoundecylphthalate can be analysed in solvent wipe samples as described in Annex B. Solvent wipe samples are suitable for non-quantitative source identification. NOTE In principle, the method is also suitable for the analysis of other phthalates, adipates and cyclohexane dicarboxylic acid esters, but this is confirmed by determination of the performance characteristics in each case. General information on phthalates are given in Annex A.