1223/2009 - Commission communication in the framework of the implementation of Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products

This proposal described a set of HPLC/UV procedures for the identification and quantitative determination in cosmetic products of 22 organic UV filters authorized in the EU: Camphor Benzalkonium Methosulfate (CBM), Homosalate (HS), Benzophenone-3 (BZ3), Phenylbenzimidazole Sulfonic Acid (PBS), Terephthalylidene Dicamphor Sulfonic Acid (TDS), Butyl Methoxydibenzoylmethane (BDM), Octocrylene (OCR), Ethylhexyl Methoxycinnamate (EMC), PEG-25 PABA (P25), Isoamyl p-Methoxycinnamate (IMC), Ethylhexyl Triazone (ET), Drometrizole Trisiloxane (DRT), Diethylhexyl Butamido Triazone (DBT), 4-Methylbenzylidene Camphor (MBC), Ethylhexyl Salicylate (ES), Ethylhexyl Dimethyl PABA (EDP), Benzophenone-4/Benzophenone-5 (BZ4),  Methylene Bis-Benzotriazolyl Tetramethylbutylphenol (MBP), Disodium Phenyl Dibenzimidazole Tetrasulfonate (PDT), Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine (EMT), Polysilicone-15 (P-15), Diethylamino Hydroxybenzoyl Hexyl Benzoate (DHHB). They are all the currently authorized organic UV filters in the EU, with the only exception of three of them that are protected under patents and are no longer used in cosmetics (Benzylidene Camphor Sulfonic Acid, Polyacrylamidomethyl Benzylidene Camphor and 3-Benzylidene Camphor).

This document specifies an analytical method, based on liquid-chromatography (LC) with ultraviolet/visible spectrometry (UV/Vis) detection for the detection and quantitative determination of 22 organic UV filters in use in the EU framework. This method has been validated for emulsion-based cosmetic products, lip-balms, lotions and waters.

This European Standard specifies a HPLC/UV method for the assay of hydroquinone, 3 ethers of hydroquinone and 4 corticosteroids most frequently found in illegally sold skin whitening cosmetic products: clobetasol propionate, betamethasone dipropionate, fluocinonide and fluocinolone acetonide.
This standard also proposes HPLC/UV methods for the identification of 38 corticosteroids may be found in skin whitening products. Indeed, as corticosteroids could be deliberately introduced in skin whitening cosmetics, despite the fact that they are forbidden to use, an identification of the presence of one of this illicit compounds could be enough for a market survey control.
This standard is not dedicated to artificial nail products or soaps.

This European Standard specifies a HPLC/UV method for the identification and quantification of hydroquinone, 3 ethers of hydroquinone and 4 corticosteroids most frequently found in illegally sold skin whitening cosmetic products: clobetasol propionate, betamethasone dipropionate, fluocinonide and fluocinolone acetonide.
This standard also gives HPLC/UV methods for the identification of 38 corticosteroids that may be found in skin whitening cosmetic products (see Annex D).
This standard is not dedicated to artificial nail products or soaps.

This International Standard specifies a screening method for the erosion potential of non-fluoridated oral rinses on dental hard tissues. The results of the screening method are intended for use in enamel and/or dentine erosion models.

ISO 28888:2013 specifies a screening method for the erosion potential of non-fluoridated oral rinses on dental hard tissues. The results of the screening method are intended for use in enamel and/or dentine erosion models.

20061004- Parallel ENQ procedure STOPPED at the request of ISO/TC 221.

ISO 22716:2007 gives guidelines for the production, control, storage and shipment of cosmetic products.
These guidelines cover the quality aspects of the product, but as a whole do not cover safety aspects for the personnel engaged in the plant, nor do they cover aspects of protection of the environment.
The guidelines in ISO 22716:2007 are not applicable to research and development activities and distribution of finished products.

- Selection of the metallic elements of interest
- Selection or development of a reliable method for determination of these elements in cosmetic products which minimizes risk of interferences and allows the appropriate levels to be measured.
- Validation and characterization of the analytical method to assess its performance (global precision) at the appropriate level.

- Selection of the metallic elements of interest
- Selection or development of a reliable method for determination of these elements in cosmetic products which minimizes risk of interferences and allows the appropriate levels to be measured.
- Validation and characterization of the analytical method to assess its performance (global precision) at the appropriate level.