ASTM D6505-00(2022)

Standard Test Method for Assay of <emph type="bdit">normal</emph>-Propyl Bromide Content

SIGNIFICANCE AND USE
3.1 This test method provides an analysis in weight percent of the normal-propyl bromide concentration of virgin, formulated, or reclaimed normal-propyl bromide: compounds that co-elute with normal-propyl bromide or normal-heptane (internal standard) may interfere with this test method.
SCOPE
1.1 This test method provides a basis for the determination of the normal-propyl bromide (weight %) in the presence of stabilizers and impurities, in virgin or reclaimed normal-propyl bromide (nPB). The application range is from 50 wt % to 100 wt %.  
1.2 This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.

General Information

• Status: Published
• Publication Date: 30-Apr-2022
• ICS: 71.080.20 - Halogenated hydrocarbons
• Technical Committee: D26 - Halogenated Organic Solvents and Fire Extinguishing Agents
• Drafting Committee: D26.04 - Test Methods

Overview

ASTM D6505-00(2022) is the Standard Test Method for Assay of normal-Propyl Bromide Content. Developed by ASTM International, this test method provides a robust and reliable approach for the quantitative determination of normal-propyl bromide (nPB) content, expressed as weight percent, in virgin, formulated, or reclaimed samples. Utilized in analytical and industrial laboratories, this method is specifically designed to detect nPB in the presence of stabilizers and impurities, making it essential for quality control and certification in chemical manufacturing and solvent processing industries.

Key Topics

• Normal-Propyl Bromide Analysis: Focuses on accurately determining the weight percent of nPB ranging from 50% to 100% in various sample types, including raw, recycled, and stabilized forms.
• Gas Chromatography Methodology: Utilizes gas chromatography with an internal standard for precise quantification, ensuring reliable results even in the presence of potential interfering substances.
• Sample Types: Applies to virgin, reclaimed, and formulated nPB, accommodating a range of product sources and processing conditions.
• Precision and Reproducibility: Specifies criteria for repeatability, laboratory precision, and inter-laboratory reproducibility, supporting consistent quality standards across the industry.
• Applicability Range: Designed for samples where nPB content must be accurately determined above 50 wt%, ensuring method suitability for most commercial and industrial scenarios.

Applications

The ASTM D6505 test method is critical across several sectors:

• Quality Assurance in Chemical Manufacturing: Ensures that nPB products meet specified purity criteria, with results informing production adjustments and product certification.
• Solvent and Cleaning Industry: Supports the production and recycling of halogenated solvents where accurate assay of nPB is vital for performance and safety.
• Environmental and Regulatory Compliance: Supplies reliable assay data required for compliance with environmental and safety standards involving halogenated organic compounds.
• Research and Development: Enables the evaluation of new nPB formulations and reclamation processes, driving innovation in solvent technology and recycling.
• Third-Party Testing Laboratories: Provides a recognized and standardized procedure for independent quality verification of nPB materials.

Related Standards

For comprehensive quality control and regulatory compliance, the following associated standards are relevant:

• ASTM D6806 - Standard Practice for Analysis of Halogenated Organic Compounds in Solvents
• ASTM D5633 - Standard Test Method for Chlorinated Solvent Purity by Gas Chromatography
• ISO 17025 - General requirements for the competence of testing and calibration laboratories
• ASTM D2111 - Standard Test Methods for Specific Conductance of Halogenated Organic Solvents and Their Admixtures
• Regulatory Frameworks - Refer to local and international chemical regulation agencies for additional assay and safety compliance requirements

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Keywords: normal-propyl bromide assay, nPB content, gas chromatography, solvent purity, halogenated organic solvents, chemical quality control, ASTM D6505, analytical test method

By implementing ASTM D6505-00(2022), organizations assure the consistency, accuracy, and reliability required for the manufacture, application, and certification of normal-propyl bromide in global markets.

Standards Content (Sample)

This international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the
Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.
Designation: D6505 − 00 (Reapproved 2022)
Standard Test Method for
Assay of normal-Propyl Bromide Content
This standard is issued under the fixed designation D6505; the number immediately following the designation indicates the year of
original adoption or, in the case of revision, the year of last revision. A number in parentheses indicates the year of last reapproval. A
superscript epsilon (´) indicates an editorial change since the last revision or reapproval.
1. Scope 4.5 Crimp Top Vials—Hewlett Packard 2 mL glass crimp
top vials withTFE-fluorocarbon-lined silicone septa or equiva-
1.1 This test method provides a basis for the determination
lent.
of the normal-propyl bromide (weight %) in the presence of
stabilizers and impurities, in virgin or reclaimednormal-propyl 4.6 Volumetric Pipet—25 mL.
bromide (nPB). The application range is from 50 wt % to 100
4.7 GlassVials—32 mLglassvials(25 mmby95mm),with
wt %.
TFE-fluorocarbon-lined screw caps.
1.2 This international standard was developed in accor-
4.8 Transfer Pipets—Borosilicate glass transfer pipets.
dance with internationally recognized principles on standard-
4.9 Precision Balance, accurate to 0.1 mg.
ization established in the Decision on Principles for the
Development of International Standards, Guides and Recom-
5. Required Chemicals
mendations issued by the World Trade Organization Technical
5.1 n-Propyl Bromide (1-Bromopropane), 99+ %, Aldrich
Barriers to Trade (TBT) Committee.
Chemical Company
2. Summary of Test Method
5.2 n-Heptane (internal standard), Reagent Grade, 99.5+ %,
J.T. Baker (or equivalent)
2.1 This analytical test method describes the determination
of the assay of n-propyl bromide by gas chromatography using
5.3 Methylene Chloride, 99+ %, Aldrich Chemical Com-
an internal standard.The results are reported in weight percent.
pany (or equivalent)
3. Significance and Use
6. Suggested Analysis Conditions
3.1 This test method provides an analysis in weight percent
6.1 Chromatographic Conditions:
of the normal-propyl bromide concentration of virgin,
Injector 150 °C
formulated, or reclaimed normal-propyl bromide: compounds
Detector temperature 250 °C
that co-elute with normal-propyl bromide or normal-heptane
(internal standard) may interfere with this test method.
FID detector range most sensitive setting
Temperature 30 °C for 10 min
4. Apparatus
program 30 °C to 250 °C at 15 °C ⁄min
4.1 Gas Chromatograph—Hewlett Packard 5890 Series II
hold at 250 °C for 10 min
equipped with a split/splitless injector, a flame ionization
Carrier gas He (or N ) at 1 mL/min
detector, and an autosampler, HP, or equivalent, if available.
split flow: 25 mL/min
column head pressure: 7.5 psi
4.2 Column—30 m by 0.25 mm, 1.0 µm film thickness
AllTech AT-5, or equivalent, capillary column.
Make-up gas He (or N ) at 30 mL/min
4.3 Syringe—5 µL or 10 µL GC autosampler syringe.
Injection volume 0.5 µL
4.4 Data Acquisition and Analysis Device—VAX MULTI-
7. Analytical Procedure
CHROM or equivalent chromatography data collection and
7.1 Internal Standard Calibration Mixture—Carefully
processing system, or integrator.
weigh about 0.25 g of n-heptane internal standard and about
0.5gof n-propyl bromide into a 32 mL glass vial. Record the
actualweightsforeach.Pipet25mLofmethylenechlorideinto
This test method is under the jurisdiction of ASTM Committee D26 on
Halogenated Organic Solvents and Fire Extinguishing Agents and is the direct
this vial and cap immediately. Mix well and then transfer
responsibility of Subcommittee D26.04 on Test Methods.
approximately 1 mL of this standard solution into an autosam-
Current edition approved May 1, 2022. Published May 2022. Originally
pler vial. Cap the vial and analyze in accordance with the
approved in 2000. Last previous edition approved in 2017 as D6505–00 (2017).
DOI: 10.1520/D6505-00R22. conditions specified in the chromatographic conditions section.
Copyright © ASTM International, 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959. United States
D6505 − 00 (2022)
Inject this standard at least three times and calibrate an internal
Wtl = amount of n-heptane (internal standard) in standard
standard method in the da
...