ASTM D5400-15

Standard Test Methods for Hydroxypropylcellulose

SIGNIFICANCE AND USE
5.1 The results of this test are used for calculating the total solids in the sample; and, by common usage, all materials volatile at this test temperature are designated as moisture.  
5.2 Moisture analysis (along with residue on ignition) is a measure of the amount of active polymer in the material and must be considered when determining the amount of hydroxypropylcellulose to use in various formulations.
SCOPE
1.1 These test methods cover the testing of hydroxypropylcellulose.  
1.2 The test procedures appear in the following order:    
Sections  
Moisture  
4 – 9  
Viscosity  
10 – 16  
pH  
17 – 21  
Residue on Ignition  
22 – 28  
Hydroxypropoxy Content  
29 – 36  
1.3 The values stated in SI units are to be regarded as the standard. The values given in parentheses are for information only.  
1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use. For specific hazard statements, see 26.6.

General Information

• Status: Historical
• Publication Date: 30-Nov-2015
• ICS: 85.040 - Pulps
• Technical Committee: D01 - Paint and Related Coatings, Materials, and Applications
• Drafting Committee: D01.36 - Cellulose and Cellulose Derivatives

Standards Content (Sample)

NOTICE: This standard has either been superseded and replaced by a new version or withdrawn.
Contact ASTM International (www.astm.org) for the latest information
Designation: D5400 − 15
Standard Test Methods for
1
Hydroxypropylcellulose
This standard is issued under the fixed designation D5400; the number immediately following the designation indicates the year of
original adoption or, in the case of revision, the year of last revision.Anumber in parentheses indicates the year of last reapproval.A
superscript epsilon (´) indicates an editorial change since the last revision or reapproval.
3
1. Scope* where such specifications are available. Other grades may be
used, provided it is first ascertained that the reagent is of
1.1 These test methods cover the testing of hydroxypropy-
sufficiently high purity to permit its use without lessening the
lcellulose.
accuracy of the determination.
1.2 The test procedures appear in the following order:
3.2 Purity of Water—Unless otherwise indicated, references
Sections
to water shall be understood to mean distilled water.
Moisture 4–9
Viscosity 10–16
MOISTURE
pH 17–21
Residue on Ignition 22–28
Hydroxypropoxy Content 29–36
4. Scope
1.3 The values stated in SI units are to be regarded as the
4.1 Thistestmethodcoversthedeterminationofthevolatile
standard. The values given in parentheses are for information
content of hydroxypropylcellulose.
only.
5. Significance and Use
1.4 This standard does not purport to address all of the
safety concerns, if any, associated with its use. It is the 5.1 The results of this test are used for calculating the total
responsibility of the user of this standard to establish appro-
solids in the sample; and, by common usage, all materials
priate safety and health practices and determine the applica- volatile at this test temperature are designated as moisture.
bility of regulatory limitations prior to use. For specific hazard
5.2 Moisture analysis (along with residue on ignition) is a
statements, see 26.6.
measure of the amount of active polymer in the material and
must be considered when determining the amount of hydroxy-
2. Referenced Documents
propylcellulose to use in various formulations.
2
2.1 ASTM Standards:
6. Apparatus
D3876Test Method for Methoxyl and Hydroxypropyl Sub-
stitution in Cellulose Ether Products by Gas Chromatog- 6.1 Oven, gravity convection, capable of maintaining a
raphy
temperature of 105 6 3°C.
E70Test Method for pH of Aqueous Solutions With the
6.2 Weighing Dish, glass or aluminum, with cover, 50 mm
Glass Electrode
in diameter, 25 mm in height, or equivalent.
6.3 Analytical Balance.
3. Reagents
3.1 Purity of Reagents—Reagent grade chemicals shall be
7. Procedure
used in all tests. Unless otherwise indicated, it is intended that
7.1 Weigh about5gof sample to the nearest 0.001 g in a
all reagents shall conform to the specifications of the Commit-
tared and covered weighing dish.
tee onAnalytical Reagents of theAmerican Chemical Society,
7.2 Place it in an oven at 105 6 1°C for 3 h with the cover
removed.
7.3 Removethedishfromtheoven,immediatelyreplacethe
1
These test methods are under the jurisdiction of ASTM Committee D01 on
Paint and Related Coatings, Materials, and Applications and are the direct cover, cool in a desiccator, and weigh.
responsibility of Subcommittee D01.36 on Cellulose and Cellulose Derivatives.
Current edition approved Dec. 1, 2015. Published January 2016. Originally
3
approved in 1993. Last previous edition approved in 2013 as D5400–03(2013). Reagent Chemicals, American Chemical Society Specifications, American
DOI: 10.1520/D5400-15. Chemical Society, Washington, DC. For suggestions on the testing of reagents not
2
For referenced ASTM standards, visit the ASTM website, www.astm.org, or listed by the American Chemical Society, see Analar Standards for Laboratory
contact ASTM Customer Service at [e-mail]. For Annual Book of ASTM Chemicals, BDH Ltd., Poole, Dorset, U.K., and the United States Pharmacopeia
Standards volume information, refer to the standard’s Document Summary page on and National Formulary, U.S. Pharmacopeial Convention, Inc. (USPC), Rockville,
the ASTM website. MD.
*A Summary of Changes section appears at the end of this standard
Copyright © ASTM International, 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959. United States
1

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D5400 − 15
TABLE 1 Cylindrical Rotational Elements and Speeds
9.2 Bias—No justifiable statement on bias can be made as
(see Fig. 1)
no suitable reference material is available as a standard.
Torque
Viscosity Range, Diameter (D) Length (L) Speed
Scale
VISCOSITY
(mPa·s) (mm) (mm) (rmin)
Multiplier
10 to 80 19 65 60 1
10. Scope
20 to 160 19 65 30 2
50 to 400 10 54 60 5
10.1 This test method is an arbitrary method of determining
100 to 800 10 54 30 10
theviscosityofaqueoussolutionsofhydroxypropylcellulosein
400 to 1600 5.9 43 60 20
the viscosity range of 10 to 16 000 mPa · s (cP) at 25°C.
80
...

This document is not an ASTM standard and is intended only to provide the user of an ASTM standard an indication of what changes have been made to the previous version. Because
it may not be technically possible to adequately depict all changes accurately, ASTM recommends that users consult prior editions as appropriate. In all cases only the current version
of the standard as published by ASTM is to be considered the official document.
Designation: D5400 − 03 (Reapproved 2013) D5400 − 15
Standard Test Methods for
1
Hydroxypropylcellulose
This standard is issued under the fixed designation D5400; the number immediately following the designation indicates the year of
original adoption or, in the case of revision, the year of last revision. A number in parentheses indicates the year of last reapproval. A
superscript epsilon (´) indicates an editorial change since the last revision or reapproval.
1. Scope Scope*
1.1 These test methods cover the testing of hydroxypropylcellulose.
1.2 The test procedures appear in the following order:
Sections
Moisture 4 – 9
Viscosity 10 – 16
pH 17 – 21
Residue on Ignition 22 – 28
Hydroxypropoxy Content 29 – 36
1.3 The values stated in SI units are to be regarded as the standard. The values given in parentheses are for information only.
1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility
of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory
limitations prior to use. For specific hazard statements, see 26.6.
2. Referenced Documents
2
2.1 ASTM Standards:
D3876 Test Method for Methoxyl and Hydroxypropyl Substitution in Cellulose Ether Products by Gas Chromatography
E70 Test Method for pH of Aqueous Solutions With the Glass Electrode
3. Reagents
3.1 Purity of Reagents—Reagent grade chemicals shall be used in all tests. Unless otherwise indicated, it is intended that all
reagents shall conform to the specifications of the Committee on Analytical Reagents of the American Chemical Society, where
3
such specifications are available. Other grades may be used, provided it is first ascertained that the reagent is of sufficiently high
purity to permit its use without lessening the accuracy of the determination.
3.2 Purity of Water—Unless otherwise indicated, references to water shall be understood to mean distilled water.
MOISTURE
4. Scope
4.1 This test method covers the determination of the volatile content of hydroxypropylcellulose.
5. Significance and Use
5.1 The results of this test are used for calculating the total solids in the sample; and, by common usage, all materials volatile
at this test temperature are designated as moisture.
5.2 Moisture analysis (along with residue on ignition) is a measure of the amount of active polymer in the material and must
be considered when determining the amount of hydroxypropylcellulose to use in various formulations.
1
These test methods are under the jurisdiction of ASTM Committee D01 on Paint and Related Coatings, Materials, and Applications and are the direct responsibility of
Subcommittee D01.36 on Cellulose and Cellulose Derivatives.
Current edition approved June 1, 2013Dec. 1, 2015. Published June 2013January 2016. Originally approved in 1993. Last previous edition approved in 20082013 as
D5400 – 03 (2008).(2013). DOI: 10.1520/D5400-03R13.10.1520/D5400-15.
2
For referenced ASTM standards, visit the ASTM website, www.astm.org, or contact ASTM Customer Service at [e-mail]. For Annual Book of ASTM Standards
volume information, refer to the standard’sstandard’s Document Summary page on the ASTM website.
3
Reagent Chemicals, American Chemical Society Specifications, American Chemical Society, Washington, DC. For suggestions on the testing of reagents not listed by
the American Chemical Society, see Analar Standards for Laboratory Chemicals, BDH Ltd., Poole, Dorset, U.K., and the United States Pharmacopeia and National
Formulary, U.S. Pharmacopeial Convention, Inc. (USPC), Rockville, MD.
*A Summary of Changes section appears at the end of this standard
Copyright © ASTM International, 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA 19428-2959. United States
1

---------------------- Page: 1 ----------------------
D5400 − 15
6. Apparatus
6.1 Oven, gravity convection, capable of maintaining a temperature of 105 6 3°C.
6.2 Weighing Dish, glass or aluminum, with cover, 50 mm in diameter, 25 mm in height, or equivalent.
6.3 Analytical Balance.
7. Procedure
7.1 Weigh about 5 g of sample to the nearest 0.001 g in a tared and covered weighing dish.
7.2 Place it in an oven at 105 6 1°C for 3 h with the cover removed.
7.3 Remove the dish from the oven, immediately replace the cover, cool in a desiccator, and weigh.
8. Calculation
8.1 Calculate the percent moisture, M, as follows:
M 5 ~A/B! 3100 (1)
where:
A = mass loss on heating, g, and
B = sample used, g.
8.2 Report the moisture content to t
...