Workplace air - Gases and vapours - Requirements for evaluation of measuring procedures using pumped samplers (ISO 22065:2020)

This document specifies performance requirements and test methods under prescribed laboratory conditions for the evaluation of pumped samplers used in conjunction with an air sampling pump and of procedures using these samplers for the determination of gases and vapours in workplace atmospheres.
This document addresses requirements for method developers and/or manufacturers.
NOTE 1 For the purposes of this document, a manufacturer can be any commercial or non-commercial entity.
NOTE 2 For the sampling of semi-volatile compounds which can appear as a mixture of vapours and airborne particles in workplace atmospheres see EN 13936.
This document is applicable to pumped samplers and measuring procedures using these samplers in which sampling and analysis are carried out in separate stages.
This document is not applicable to:
—     pumped samplers which are used for the direct determination of concentrations, for example, length-of-stain detector tubes;
—     samplers which rely on sorption into a liquid, and subsequent analysis of the solution (bubblers).

Luft am Arbeitsplatz - Gase und Dämpfe - Anforderungen an die Evaluierung von Messverfahren mit pumpenbetriebenen Probenahmeeinrichtungen (ISO 22065:2020)

Dieses Dokument legt Anforderungen an die Leistungsfähigkeit und Prüfverfahren für die Evaluierung von pumpenbetriebenen Sammlern unter vorgegebenen Laborbedingungen fest, die in Verbindung mit einer Luftsammelpumpe verwendet werden, sowie von Verfahren, die diese Sammler zur Bestimmung von Gasen und Dämpfen in der Arbeitsplatzatmosphäre verwenden.
Dieses Dokument behandelt Anforderungen für Entwickler des Verfahrens und/oder Hersteller.
ANMERKUNG 1 Für den Zweck dieses Dokuments kann ein Hersteller jede kommerzielle oder nicht-kommerzielle Entität sein.
ANMERKUNG 2 Für die Probenahme von schwerflüchtigen Verbindungen, die als Mischung von Dampf und luftgetragenen Partikeln in Arbeitsplatzatmosphären auftreten können, siehe EN 13936.
Dieses Dokument gilt für pumpenbetriebene Sammler und diese Sammler verwendende Messverfahren, bei denen Probenahme und Analyse in getrennten Schritten vorgenommen werden.
Dieses Dokument gilt nicht für
- pumpenbetriebene Sammler, die zur direkten Konzentrationsbestimmung verwendet werden, z. B. Prüfröhrchen mit Längenanzeige;
- Sammler, deren Funktionsweise auf Sorption in einer Flüssigkeit und anschließender Analyse der Lösung beruht (Gaswaschflaschen).

Air des lieux de travail - Gaz et vapeurs - Exigences pour l'évaluation des procédures de mesure à l'aide de dispositifs de prélèvement par pompage (ISO 22065:2020)

Le présent document spécifie les exigences de performance et les méthodes d'essai, dans des conditions de laboratoires spécifiées, pour l'évaluation des dispositifs de prélèvement par pompage employés conjointement avec une pompe de prélèvement d'air, ainsi que pour l'évaluation des procédures utilisant ces dispositifs de prélèvement pour la détermination des gaz et des vapeurs dans les atmosphères des lieux de travail.
Le présent document traite des exigences à destination des développeurs de méthodes et/ou des fabricants.
NOTE 1    Pour les besoins du présent document, un fabricant peut être toute entité commerciale ou non commerciale.
NOTE 2    En ce qui concerne le prélèvement de composés semi-volatils pouvant exister sous forme de mélange de vapeurs et de particules aériennes au sein des atmosphères des lieux de travail, voir l'EN 13936.
Le présent document est applicable aux dispositifs de prélèvement par pompage et aux procédures de mesure utilisant ces dispositifs de prélèvement pour lesquels le prélèvement et l'analyse sont effectués dans des étapes séparées.
Le présent document n'est pas applicable:
—     aux dispositifs de prélèvement par pompage utilisés pour la détermination directe des concentrations, par exemple les tubes détecteurs à plage colorée;
—     aux dispositifs de prélèvement basés sur l'adsorption dans un liquide suivie de l'analyse de la solution (barboteurs).

Zrak na delovnem mestu - Plini in pare - Zahteve za vrednotenje postopkov za merjenje z vzorčevalniki s črpanjem (ISO 22065:2020)

General Information

Status
Published
Publication Date
24-Nov-2020
Withdrawal Date
30-May-2021
Current Stage
6060 - Definitive text made available (DAV) - Publishing
Start Date
25-Nov-2020
Completion Date
25-Nov-2020

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SLOVENSKI STANDARD
SIST EN ISO 22065:2021
01-januar-2021
Nadomešča:
SIST EN ISO 22065:2019
Zrak na delovnem mestu - Plini in pare - Zahteve za vrednotenje postopkov za
merjenje z vzorčevalniki s črpanjem (ISO 22065:2020)
Workplace air - Gases and vapours - Requirements for evaluation of measuring
procedures using pumped samplers (ISO 22065:2020)
Arbeitsplatzatmosphäre - Gase und Dämpfe - Anforderungen und Prüfverfahren zur
Messung mit pumpenbetriebenen Probenahmeeinrichtungen (ISO 22065:2020)
Air des lieux de travail - Gaz et vapeurs - Exigences pour l'évaluation des procédures de
mesure à l'aide de dispositifs de prélèvement par pompage (ISO 22065:2020)
Ta slovenski standard je istoveten z: EN ISO 22065:2020
ICS:
13.040.30 Kakovost zraka na delovnem Workplace atmospheres
mestu
SIST EN ISO 22065:2021 en,fr,de
2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.

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SIST EN ISO 22065:2021

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SIST EN ISO 22065:2021


EN ISO 22065
EUROPEAN STANDARD

NORME EUROPÉENNE

November 2020
EUROPÄISCHE NORM
ICS 13.040.30 Supersedes EN ISO 22065:2019
English Version

Workplace air - Gases and vapours - Requirements for
evaluation of measuring procedures using pumped
samplers (ISO 22065:2020)
Air des lieux de travail - Gaz et vapeurs - Exigences Arbeitsplatzatmosphäre - Gase und Dämpfe -
pour l'évaluation des procédures de mesure à l'aide de Anforderungen und Prüfverfahren zur Messung mit
dispositifs de prélèvement par pompage (ISO pumpenbetriebenen Probenahmeeinrichtungen (ISO
22065:2020) 22065:2020)
This European Standard was approved by CEN on 17 October 2020.

CEN members are bound to comply with the CEN/CENELEC Internal Regulations which stipulate the conditions for giving this
European Standard the status of a national standard without any alteration. Up-to-date lists and bibliographical references
concerning such national standards may be obtained on application to the CEN-CENELEC Management Centre or to any CEN
member.

This European Standard exists in three official versions (English, French, German). A version in any other language made by
translation under the responsibility of a CEN member into its own language and notified to the CEN-CENELEC Management
Centre has the same status as the official versions.

CEN members are the national standards bodies of Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia,
Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway,
Poland, Portugal, Republic of North Macedonia, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey and
United Kingdom.





EUROPEAN COMMITTEE FOR STANDARDIZATION
COMITÉ EUROPÉEN DE NORMALISATION

EUROPÄISCHES KOMITEE FÜR NORMUNG

CEN-CENELEC Management Centre: Rue de la Science 23, B-1040 Brussels
© 2020 CEN All rights of exploitation in any form and by any means reserved Ref. No. EN ISO 22065:2020 E
worldwide for CEN national Members.

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SIST EN ISO 22065:2021
EN ISO 22065:2020 (E)
Contents Page
European foreword . 3

2

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SIST EN ISO 22065:2021
EN ISO 22065:2020 (E)
European foreword
This document (EN ISO 22065:2020) has been prepared by Technical Committee ISO/TC 146 "Air
quality" in collaboration with Technical Committee CEN/TC 137 “Assessment of workplace exposure to
chemical and biological agents” the secretariat of which is held by DIN.
This European Standard shall be given the status of a national standard, either by publication of an
identical text or by endorsement, at the latest by May 2021, and conflicting national standards shall be
withdrawn at the latest by May 2021.
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. CEN shall not be held responsible for identifying any or all such patent rights.
This document supersedes EN ISO 22065:2019.
According to the CEN-CENELEC Internal Regulations, the national standards organizations of the
following countries are bound to implement this European Standard: Austria, Belgium, Bulgaria,
Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland,
Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Republic of
North Macedonia, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey and the
United Kingdom.
Endorsement notice
The text of ISO 22065:2020 has been approved by CEN as EN ISO 22065:2020 without any modification.

3

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SIST EN ISO 22065:2021

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SIST EN ISO 22065:2021
INTERNATIONAL ISO
STANDARD 22065
Second edition
2020-11
Workplace air — Gases and vapours
— Requirements for evaluation of
measuring procedures using pumped
samplers
Air des lieux de travail — Gaz et vapeurs — Exigences pour
l'évaluation des procédures de mesure à l'aide de dispositifs de
prélèvement par pompage
Reference number
ISO 22065:2020(E)
©
ISO 2020

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SIST EN ISO 22065:2021
ISO 22065:2020(E)

COPYRIGHT PROTECTED DOCUMENT
© ISO 2020
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may
be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting
on the internet or an intranet, without prior written permission. Permission can be requested from either ISO at the address
below or ISO’s member body in the country of the requester.
ISO copyright office
CP 401 • Ch. de Blandonnet 8
CH-1214 Vernier, Geneva
Phone: +41 22 749 01 11
Email: copyright@iso.org
Website: www.iso.org
Published in Switzerland
ii © ISO 2020 – All rights reserved

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SIST EN ISO 22065:2021
ISO 22065:2020(E)

Contents Page
Foreword .v
Introduction .vi
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Symbols and abbreviated terms . 2
5 Sampler types . 3
6 Requirements . 3
6.1 General . 3
6.2 Sampler requirements . 3
6.2.1 Flow resistance . 3
6.2.2 Sampler leak test (for Type B samplers) . 4
6.2.3 Shelf life . 5
6.2.4 Sampler identification . 5
6.2.5 Marking . 5
6.2.6 Instructions for use. 5
6.3 Measuring procedure requirements . 5
6.3.1 Sampling procedure requirements . 5
6.3.2 Analytical procedure requirements . 6
6.3.3 Expanded uncertainty . 7
6.3.4 Method description . 7
7 General test conditions . 8
7.1 Reagents. 8
7.2 Apparatus . 8
7.3 Calibration gas mixture . 8
7.3.1 Generation . 8
7.3.2 Determination of mass concentration . 9
7.3.3 Independent method . 9
8 Test methods . 9
8.1 General . 9
8.2 Sampler test methods .10
8.2.1 Flow resistance .10
8.2.2 Sampler leak test (for Type B samplers) .10
8.2.3 Shelf life (for Type A impregnated supports) .10
8.2.4 Sampler identification .11
8.2.5 Marking .11
8.2.6 Instructions for use.11
8.3 Measuring procedure test methods .11
8.3.1 Determination of the recommended sampling conditions .11
8.3.2 Analytical procedure test methods .14
8.3.3 Method recovery and method precision .15
8.4 Uncertainty of measurement .17
8.4.1 Identification of random and non-random uncertainty components .17
8.4.2 Estimation of individual uncertainty components .17
8.4.3 Calculation of expanded uncertainty .19
9 Test report .19
Annex A (informative) Examples for the determination of the breakthrough volume .20
Annex B (informative) Experiments for method validation .22
Annex C (informative) Estimation of uncertainty of measurement .24
© ISO 2020 – All rights reserved iii

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SIST EN ISO 22065:2021
ISO 22065:2020(E)

Annex D (informative) Example for estimation of expanded uncertainty .34
Bibliography .37
iv © ISO 2020 – All rights reserved

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SIST EN ISO 22065:2021
ISO 22065:2020(E)

Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards
bodies (ISO member bodies). The work of preparing International Standards is normally carried out
through ISO technical committees. Each member body interested in a subject for which a technical
committee has been established has the right to be represented on that committee. International
organizations, governmental and non-governmental, in liaison with ISO, also take part in the work.
ISO collaborates closely with the International Electrotechnical Commission (IEC) on all matters of
electrotechnical standardization.
The procedures used to develop this document and those intended for its further maintenance are
described in the ISO/IEC Directives, Part 1. In particular, the different approval criteria needed for the
different types of ISO documents should be noted. This document was drafted in accordance with the
editorial rules of the ISO/IEC Directives, Part 2 (see www .iso .org/ directives).
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. ISO shall not be held responsible for identifying any or all such patent rights. Details of
any patent rights identified during the development of the document will be in the Introduction and/or
on the ISO list of patent declarations received (see www .iso .org/ patents).
Any trade name used in this document is information given for the convenience of users and does not
constitute an endorsement.
For an explanation of the voluntary nature of standards, the meaning of ISO specific terms and
expressions related to conformity assessment, as well as information about ISO's adherence to the
World Trade Organization (WTO) principles in the Technical Barriers to Trade (TBT) see www .iso .org/
iso/ foreword .html.
This document was prepared by Technical Committee ISO/TC 146, Air quality, Subcommittee SC 2,
Workplace atmospheres.
This second edition cancels and replaces the first edition (ISO 22065:2019), of which it constitutes a
minor revision. The changes compared to the previous edition are as follows:
— Editorial updates.
Any feedback or questions on this document should be directed to the user’s national standards body. A
complete listing of these bodies can be found at www .iso .org/ members .html.
© ISO 2020 – All rights reserved v

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SIST EN ISO 22065:2021
ISO 22065:2020(E)

Introduction
This document provides a framework for assessing the performance of procedures for measuring
gases and vapours against the general requirements for the performance of procedures for measuring
chemical agents in workplace atmospheres as specified in ISO 20581. It enables manufacturers and
users of pumped samplers and developers and users of procedures for measuring gases and vapours to
adopt a consistent approach to method validation (see Annex B).
vi © ISO 2020 – All rights reserved

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SIST EN ISO 22065:2021
INTERNATIONAL STANDARD ISO 22065:2020(E)
Workplace air — Gases and vapours — Requirements
for evaluation of measuring procedures using pumped
samplers
1 Scope
This document specifies performance requirements and test methods under prescribed laboratory
conditions for the evaluation of pumped samplers used in conjunction with an air sampling pump and of
procedures using these samplers for the determination of gases and vapours in workplace atmospheres.
This document addresses requirements for method developers and/or manufacturers.
NOTE 1 For the purposes of this document, a manufacturer can be any commercial or non-commercial entity.
NOTE 2 For the sampling of semi-volatile compounds which can appear as a mixture of vapours and airborne
particles in workplace atmospheres see EN 13936.
This document is applicable to pumped samplers and measuring procedures using these samplers in
which sampling and analysis are carried out in separate stages.
This document is not applicable to:
— pumped samplers which are used for the direct determination of concentrations, for example,
length-of-stain detector tubes;
— samplers which rely on sorption into a liquid, and subsequent analysis of the solution (bubblers).
2 Normative references
The following documents are referred to in the text in such a way that some or all of their content
constitutes requirements of this document. For dated references, only the edition cited applies. For
undated references, the latest edition of the referenced document (including any amendments) applies.
ISO 8655-2, Piston-operated volumetric apparatus — Part 2: Piston pipettes
ISO 8655-6, Piston-operated volumetric apparatus — Part 6: Gravimetric methods for the determination
of measurement error
ISO 13137:2013, Workplace atmospheres — Pumps for personal sampling of chemical and biological
agents — Requirements and test methods
ISO 18158, Workplace air — Terminology
ISO 20581, Workplace air — General requirements for the performance of procedures for the measurement
of chemical agents
3 Terms and definitions
For the purposes of this document, the terms and definitions given in ISO 18158 apply.
ISO and IEC maintain terminological databases for use in standardization at the following addresses:
— ISO Online browsing platform: available at https:// www .iso .org/ obp
— IEC Electropedia: available at http:// www .electropedia .org/
© ISO 2020 – All rights reserved 1

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SIST EN ISO 22065:2021
ISO 22065:2020(E)

4 Symbols and abbreviated terms
For the purposes of this document, the following symbols and abbreviations apply.
NOTE See 8.4 and Annex C for symbols used in conjunction with uncertainty of measurement only.
CRM certified reference material
LV limit value
m mass of analyte desorbed from tube blank, in micrograms (µg)
a1
m mass of analyte desorbed from spiked tube, in micrograms (µg)
a2
m maximum mass uptake of analyte in a leak test performed on a sealed sampler used for
a,lt
making measurements for comparison with a long-term limit value, in milligrams (mg)
m maximum mass uptake of analyte in a leak test performed on a sealed sampler used for
a,st
making measurements for comparison with a short-term limit value, in milligrams (mg)
−1

m mass loss from permeation tube, in micrograms per minute (µg ∙ min )
1
−1
M molar mass of analyte, in grams per mole (g ∙ mol )
a
n number of replicate samples
p pressure of the test atmosphere sampled, in kilopascals (kPa)
at
R method recovery
me
R analytical recovery
an
RH relative humidity of the test atmosphere sampled, in percent (%)
t hold-up time of the unretained substance, in minutes (min)
H
t sampling time, in minutes (min)
s
T temperature of the test atmosphere sampled, in Kelvins (K)
at
V volume of the test atmosphere sampled, in litres (l)
at
V gas (vapour) hold-up volume (dead volume), in litres (l)
H
V uncorrected retention volume, in litres (l)
R
(V )′ corrected retention volume, in litres (l)
R
−1
v
flow rate into the exposure chamber, for example, in litres per minute (l ∙ min )
−1
v volumetric air flow rate through the sampler, for example, in litres per minute (l ∙ min )
a
β mass concentration of the analyte in the calibration gas mixture, in milligrams per cubic
a
−3
metre (mg ∙ m )
mean mass concentration of the analyte recovered from the test gas atmosphere, in mil-
β
a,R
−3
ligrams per cubic metre (mg ∙ m )
2 © ISO 2020 – All rights reserved

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SIST EN ISO 22065:2021
ISO 22065:2020(E)

β mass concentration of the calibration gas mixture, in milligrams per cubic metre
cg
−3
(mg ∙ m )
ϑ temperature of the test atmosphere sampled, in degrees Celsius (°C)
at
K coefficient of variation (CV)
v
NOTE  The predecessor term "relative standard deviation" is deprecated. See also
ISO 3534-1:2006, 2.38, Note 2.
−3
ρ long-term limit value given as concentration, in milligrams per cubic metre (mg ∙ m )
LV,lt
−3
ρ short-term limit value given as concentration, in milligrams per cubic metre (mg ∙ m )
LV,st
−1
ϕ volume fraction of the analyte, in microlitres per litre (µl ∙ l )
a
5 Sampler types
Samplers for gases and vapours can be divided into type A samplers and type B samplers:
— Type A samplers rely on sorption onto a collection substrate which can be impregnated with a
reagent. The collection substrate is always desorbed with a solvent, and subsequently analysed.
— Type B samplers rely on sorption onto a solid, thermal desorption, and analysis of the desorbate.
6 Requirements
6.1 General
Some requirements (see 6.2) shall be initially verified by the manufacturer once for each type of
sampler. Other requirements (see 6.3) shall be verified for each combination sampler/chemical agent.
Measuring procedures shall meet the requirements for measuring procedures specified in 6.3. When
use of a sampler for measurement of a particular gas or vapour is claimed, the sampler shall meet the
requirements specified in 6.2.
Known or suspected interferences shall be noted as required in 6.3.4.1. The results of any tests
performed to evaluate interferences, including suitable and sufficient information to minimize their
effects shall be presented in the method report as required in 6.3.4.2.
NOTE No useful performance requirements can be given for the effect of interferents (with the exception
of water vapour). The effect of interferents is difficult to predict for a non-ideal sorbent without adsorption
isotherm data on mixed systems which is normally unavailable.
6.2 Sampler requirements
6.2.1 Flow resistance
When tested in accordance with 8.2.1, at least 95 % of samplers shall have a back pressure less than the
appropriate maximum value indicated in Table 1. A minimum of 20 samplers shall be tested.
NOTE Typical back pressure values for type A samplers and type B samplers are given in [1].
© ISO 2020 – All rights reserved 3

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SIST EN ISO 22065:2021
ISO 22065:2020(E)

Table 1 — Maximum back pressures
Maximum back
Sampler type pressure
kPa
Type A (solvent desorption) ≤10
Type B (thermal desorption) ≤3,5
6.2.2 Sampler leak test (for Type B samplers)
When tested in accordance with 8.2.2, for substances with a long-term limit value the maximum
leakage, i.e. the maximum mass uptake of analyte above the blank value (see 6.3.2.3), shall be less than
m calculated according to Formula (1), in milligrams (mg), as follows:
a,lt
1
−3
m =×01,,ρ 240××00110 (1)
()
a,lt LV,lt
3
where
m is the maximum mass uptake of analyte in a leak test performed on a sealed sampler used
a,lt
for making measurements for comparison with a long-term limit value;
ρ is the long-term limit value of the substance given as concentration, in milligrams per cubic
LV,lt
−3
metre (mg ∙ m );
240 is the reference period, in minutes (min);
−1
0,01 is the nominal minimum flow rate for type B samplers, in litres per minute (l ∙ min );
−3
10 is a factor applied to convert the nominal minimum flow rate from litres per minute (l/min)
3 −1
to cubic metres per minute (m ∙ min );
1/3 is a factor applied to calculate the maximum permitted leakage.
When tested in accordance with 8.2.2, for substances with a short-term limit value the maximum
leakage, i.e. the maximum mass uptake of analyte above the blank value (see 6.3.2.3), shall be less than
m calculated according to Formula (2), in milligrams (mg), as follows:
a,st
1
−3
m =×05,,ρ 15××00110 (2)
()
a,st LV,st
3
where
m is the maximum mass uptake of analyte in a leak test performed on a sealed sampler used
a,st
for making measurements for comparison with a short-term limit value;
ρ is the short-term limit value of the substance given as concentration, in milligrams per cubic
LV,st
−3
metre (mg ∙ m );
15 is the reference period, in minutes (min);
−1
0,01 is the nominal minimum flow rate for type B samplers, in litres per minute (l ∙ min );
−3
10 is a factor applied to convert the nominal minimum flow rate from litres per minute
−1 3 −1
(l ∙ min ) to cubic metres per minute (m ∙ min );
1/3 is a factor applied to calculate the maximum permitted leakage.
4 © ISO 2020 – All rights reserved

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SIST EN ISO 22065:2021
ISO 22065:2020(E)

6.2.3 Shelf life
The manufacturer shall specify the shelf life of the sampler when stored in its original package. During
this period the sampler shall fulfil all requirements.
6.2.4 Sampler identification
Samplers shall be uniquely identified.
6.2.5 Marking
Samplers shall be marked with at least the following:
a) manufacturer’s name,
b) product identification including batch identification, where available,
c) indication of the direction of air flow,
d) shelf life (or expiry date), and
e) number of this document.
NOTE The marking with the number of this document implies only that the sampler fulfils the requirements
given in 6.2.
If required due to limited space, the marking may be placed on the packaging of the sampler. However,
at least the product identification, batch identification, where available, and direction of air flow shall
be indicated on the sampler.
6.2.6 Instructions for use
The instructions for use supplied with the sampler shall be written in the principal language(s) used in
the countries where the sampler is to be marketed. They shall contain at least the following information:
a) designated use (general purpose for a number of gases and vapours or, specific, for a particular gas
or vapour, see 6.1),
b) assurance that blank value meets specifications, where necessary for a particular gas or vapour,
(where a blank value is important),
c) directions for proper handling of the sampler, including opening and closing,
d) general information on the principle of use, for example, sorbent type, reaction of the reagent
impregnate
...

SLOVENSKI STANDARD
oSIST prEN ISO 22065:2020
01-september-2020
Zrak na delovnem mestu - Plini in pare - Zahteve za vrednotenje postopkov za
merjenje z vzorčevalniki s črpanjem (ISO/FDIS 22065:2020)
Workplace air - Gases and vapours - Requirements for evaluation of measuring
procedures using pumped samplers (ISO/FDIS 22065:2020)
Arbeitsplatzatmosphäre - Gase und Dämpfe - Anforderungen und Prüfverfahren zur
Messung mit pumpenbetriebenen Probenahmeeinrichtungen (ISO/FDIS 22065:2020)
Air des lieux de travail - Gaz et vapeurs - Exigences pour l'évaluation des procédures de
mesure à l'aide de dispositifs de prélèvement par pompage (ISO/FDIS 22065:2020)
Ta slovenski standard je istoveten z: prEN ISO 22065
ICS:
13.040.30 Kakovost zraka na delovnem Workplace atmospheres
mestu
oSIST prEN ISO 22065:2020 en,fr,de
2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.

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oSIST prEN ISO 22065:2020

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oSIST prEN ISO 22065:2020
FINAL
INTERNATIONAL ISO/FDIS
DRAFT
STANDARD 22065
ISO/TC 146/SC 2
Workplace air — Gases and vapours
Secretariat: ANSI
— Requirements for evaluation of
Voting begins on:
2020­06­24 measuring procedures using pumped
samplers
Voting terminates on:
2020­09­16
Air des lieux de travail — Gaz et vapeurs — Exigences pour
l'évaluation des procédures de mesure à l'aide de dispositifs de
prélèvement par pompage
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ISO/FDIS 22065:2020(E)
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NATIONAL REGULATIONS. ISO 2020

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oSIST prEN ISO 22065:2020
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© ISO 2020
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oSIST prEN ISO 22065:2020
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Contents Page
Foreword .v
Introduction .vi
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Symbols and abbreviated terms . 2
5 Sampler types . 3
6 Requirements . 3
6.1 General . 3
6.2 Sampler requirements . 3
6.2.1 Flow resistance . 3
6.2.2 Sampler leak test (for Type B samplers) . 4
6.2.3 Shelf life . 5
6.2.4 Sampler identification . 5
6.2.5 Marking . 5
6.2.6 Instructions for use. 5
6.3 Measuring procedure requirements . 5
6.3.1 Sampling procedure requirements . 5
6.3.2 Analytical procedure requirements . 6
6.3.3 Expanded uncertainty . 7
6.3.4 Method description . 7
7 General test conditions . 8
7.1 Reagents. 8
7.2 Apparatus . 8
7.3 Calibration gas mixture . 8
7.3.1 Generation . 8
7.3.2 Determination of mass concentration . 9
7.3.3 Independent method . 9
8 Test methods . 9
8.1 General . 9
8.2 Sampler test methods .10
8.2.1 Flow resistance .10
8.2.2 Sampler leak test (for Type B samplers) .10
8.2.3 Shelf life (for Type A impregnated supports) .10
8.2.4 Sampler identification .11
8.2.5 Marking .11
8.2.6 Instructions for use.11
8.3 Measuring procedure test methods .11
8.3.1 Determination of the recommended sampling conditions .11
8.3.2 Analytical procedure test methods .14
8.3.3 Method recovery and method precision .15
8.4 Uncertainty of measurement .17
8.4.1 Identification of random and non-random uncertainty components .17
8.4.2 Estimation of individual uncertainty components .17
8.4.3 Calculation of expanded uncertainty .19
9 Test report .19
Annex A (informative) Examples for the determination of the breakthrough volume .20
Annex B (informative) Experiments for method validation .22
Annex C (informative) Estimation of uncertainty of measurement .24
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Annex D (informative) Example for estimation of expanded uncertainty .34
Bibliography .37
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oSIST prEN ISO 22065:2020
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Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards
bodies (ISO member bodies). The work of preparing International Standards is normally carried out
through ISO technical committees. Each member body interested in a subject for which a technical
committee has been established has the right to be represented on that committee. International
organizations, governmental and non­governmental, in liaison with ISO, also take part in the work.
ISO collaborates closely with the International Electrotechnical Commission (IEC) on all matters of
electrotechnical standardization.
The procedures used to develop this document and those intended for its further maintenance are
described in the ISO/IEC Directives, Part 1. In particular, the different approval criteria needed for the
different types of ISO documents should be noted. This document was drafted in accordance with the
editorial rules of the ISO/IEC Directives, Part 2 (see www .iso .org/ directives).
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. ISO shall not be held responsible for identifying any or all such patent rights. Details of
any patent rights identified during the development of the document will be in the Introduction and/or
on the ISO list of patent declarations received (see www .iso .org/ patents).
Any trade name used in this document is information given for the convenience of users and does not
constitute an endorsement.
For an explanation of the voluntary nature of standards, the meaning of ISO specific terms and
expressions related to conformity assessment, as well as information about ISO's adherence to the
World Trade Organization (WTO) principles in the Technical Barriers to Trade (TBT) see www .iso .org/
iso/ foreword .html.
This document was prepared by Technical Committee ISO/TC 146, Air quality, Subcommittee SC 2,
Workplace atmospheres.
Any feedback or questions on this document should be directed to the user’s national standards body. A
complete listing of these bodies can be found at www .iso .org/ members .html.
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Introduction
This document provides a framework for assessing the performance of procedures for measuring
gases and vapours against the general requirements for the performance of procedures for measuring
chemical agents in workplace atmospheres as specified in ISO 20581. It enables manufacturers and
users of pumped samplers and developers and users of procedures for measuring gases and vapours to
adopt a consistent approach to method validation (see Annex B).
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oSIST prEN ISO 22065:2020
FINAL DRAFT INTERNATIONAL STANDARD ISO/FDIS 22065:2020(E)
Workplace air — Gases and vapours — Requirements
for evaluation of measuring procedures using pumped
samplers
1 Scope
This document specifies performance requirements and test methods under prescribed laboratory
conditions for the evaluation of pumped samplers used in conjunction with an air sampling pump and of
procedures using these samplers for the determination of gases and vapours in workplace atmospheres.
This document addresses requirements for method developers and/or manufacturers.
NOTE 1 For the purposes of this document, a manufacturer can be any commercial or non-commercial entity.
NOTE 2 For the sampling of semi-volatile compounds which can appear as a mixture of vapours and airborne
particles in workplace atmospheres see EN 13936.
This document is applicable to pumped samplers and measuring procedures using these samplers in
which sampling and analysis are carried out in separate stages.
This document is not applicable to:
— pumped samplers which are used for the direct determination of concentrations, for example,
length­of­stain detector tubes;
— samplers which rely on sorption into a liquid, and subsequent analysis of the solution (bubblers).
2 Normative references
The following documents are referred to in the text in such a way that some or all of their content
constitutes requirements of this document. For dated references, only the edition cited applies. For
undated references, the latest edition of the referenced document (including any amendments) applies.
ISO 8655­2, Piston-operated volumetric apparatus — Part 2: Piston pipettes
ISO 8655­6, Piston-operated volumetric apparatus — Part 6: Gravimetric methods for the determination
of measurement error
ISO 13137:2013, Workplace atmospheres — Pumps for personal sampling of chemical and biological
agents — Requirements and test methods
ISO 18158, Workplace air — Terminology
ISO 20581, Workplace air — General requirements for the performance of procedures for the measurement
of chemical agents
3 Terms and definitions
For the purposes of this document, the terms and definitions given in ISO 18158 apply.
ISO and IEC maintain terminological databases for use in standardization at the following addresses:
— ISO Online browsing platform: available at https:// www .iso .org/ obp
— IEC Electropedia: available at http:// www .electropedia .org/
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4 Symbols and abbreviated terms
For the purposes of this document, the following symbols and abbreviations apply.
NOTE See 8.4 and Annex C for symbols used in conjunction with uncertainty of measurement only.
CRM certified reference material
LV limit value
m mass of analyte desorbed from tube blank, in micrograms (µg)
a1
m mass of analyte desorbed from spiked tube, in micrograms (µg)
a2
m maximum mass uptake of analyte in a leak test performed on a sealed sampler used for
a,lt
making measurements for comparison with a long­term limit value, in milligrams (mg)
m maximum mass uptake of analyte in a leak test performed on a sealed sampler used for
a,st
making measurements for comparison with a short­term limit value, in milligrams (mg)
−1

m mass loss from permeation tube, in micrograms per minute (µg ∙ min )
1
−1
M molar mass of analyte, in grams per mole (g ∙ mol )
a
n number of replicate samples
p pressure of the test atmosphere sampled, in kilopascals (kPa)
at
R method recovery
me
R analytical recovery
an
RH relative humidity of the test atmosphere sampled, in percent (%)
t hold­up time of the unretained substance, in minutes (min)
H
t sampling time, in minutes (min)
s
T temperature of the test atmosphere sampled, in Kelvins (K)
at
V volume of the test atmosphere sampled, in litres (l)
at
V gas (vapour) hold­up volume (dead volume), in litres (l)
H
V uncorrected retention volume, in litres (l)
R
(V )′ corrected retention volume, in litres (l)
R
−1
v
flow rate into the exposure chamber, for example, in litres per minute (l ∙ min )
−1
v volumetric air flow rate through the sampler, for example, in litres per minute (l ∙ min )
a
β mass concentration of the analyte in the calibration gas mixture, in milligrams per cubic
a
−3
metre (mg ∙ m )
mean mass concentration of the analyte recovered from the test gas atmosphere, in mil­
β
a,R
−3
ligrams per cubic metre (mg ∙ m )
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β mass concentration of the calibration gas mixture, in milligrams per cubic metre
cg
−3
(mg ∙ m )
ϑ temperature of the test atmosphere sampled, in degrees Celsius (°C)
at
K coefficient of variation (CV)
v
NOTE  The predecessor term "relative standard deviation" is deprecated. See also
ISO 3534­1:2006, 2.38, Note 2.
−3
ρ long-term limit value given as concentration, in milligrams per cubic metre (mg ∙ m )
LV,lt
−3
ρ short-term limit value given as concentration, in milligrams per cubic metre (mg ∙ m )
LV,st
−1
ϕ volume fraction of the analyte, in microlitres per litre (µl ∙ l )
a
5 Sampler types
Samplers for gases and vapours can be divided into type A samplers and type B samplers:
— Type A samplers rely on sorption onto a collection substrate which can be impregnated with a
reagent. The collection substrate is always desorbed with a solvent, and subsequently analysed.
— Type B samplers rely on sorption onto a solid, thermal desorption, and analysis of the desorbate.
6 Requirements
6.1 General
Some requirements (see 6.2) shall be initially verified by the manufacturer once for each type of
sampler. Other requirements (see 6.3) shall be verified for each combination sampler/chemical agent.
Measuring procedures shall meet the requirements for measuring procedures specified in 6.3. When
use of a sampler for measurement of a particular gas or vapour is claimed, the sampler shall meet the
requirements specified in 6.2.
Known or suspected interferences shall be noted as required in 6.3.4.1. The results of any tests
performed to evaluate interferences, including suitable and sufficient information to minimize their
effects shall be presented in the method report as required in 6.3.4.2.
NOTE No useful performance requirements can be given for the effect of interferents (with the exception
of water vapour). The effect of interferents is difficult to predict for a non-ideal sorbent without adsorption
isotherm data on mixed systems which is normally unavailable.
6.2 Sampler requirements
6.2.1 Flow resistance
When tested in accordance with 8.2.1, at least 95 % of samplers shall have a back pressure less than the
appropriate maximum value indicated in Table 1. A minimum of 20 samplers shall be tested.
NOTE Typical back pressure values for type A samplers and type B samplers are given in [1].
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Table 1 — Maximum back pressures
Maximum back
Sampler type pressure
kPa
Type A (solvent desorption) ≤10
Type B (thermal desorption) ≤3,5
6.2.2 Sampler leak test (for Type B samplers)
When tested in accordance with 8.2.2, for substances with a long-term limit value the maximum
leakage, i.e. the maximum mass uptake of analyte above the blank value (see 6.3.2.3), shall be less than
m calculated according to Formula (1), in milligrams (mg), as follows:
a,lt
1
−3
m =×01,,ρ 240××00110 (1)
()
a,lt LV,lt
3
where
m is the maximum mass uptake of analyte in a leak test performed on a sealed sampler used
a,lt
for making measurements for comparison with a long­term limit value;
ρ is the long­term limit value of the substance given as concentration, in milligrams per cubic
LV,lt
−3
metre (mg ∙ m );
240 is the reference period, in minutes (min);
−1
0,01 is the nominal minimum flow rate for type B samplers, in litres per minute (l ∙ min );
−3
10 is a factor applied to convert the nominal minimum flow rate from litres per minute (l/min)
3 −1
to cubic metres per minute (m ∙ min );
1/3 is a factor applied to calculate the maximum permitted leakage.
When tested in accordance with 8.2.2, for substances with a short-term limit value the maximum
leakage, i.e. the maximum mass uptake of analyte above the blank value (see 6.3.2.3), shall be less than
m calculated according to Formula (2), in milligrams (mg), as follows:
a,st
1
−3
m =×05,,ρ 15××00110 (2)
()
a,st LV,st
3
where
m is the maximum mass uptake of analyte in a leak test performed on a sealed sampler used
a,st
for making measurements for comparison with a short­term limit value;
ρ is the short­term limit value of the substance given as concentration, in milligrams per cubic
LV,st
−3
metre (mg ∙ m );
15 is the reference period, in minutes (min);
−1
0,01 is the nominal minimum flow rate for type B samplers, in litres per minute (l ∙ min );
−3
10 is a factor applied to convert the nominal minimum flow rate from litres per minute
−1 3 −1
(l ∙ min ) to cubic metres per minute (m ∙ min );
1/3 is a factor applied to calculate the maximum permitted leakage.
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6.2.3 Shelf life
The manufacturer shall specify the shelf life of the sampler when stored in its original package. During
this period the sampler shall fulfil all requirements.
6.2.4 Sampler identification
Samplers shall be uniquely identified.
6.2.5 Marking
Samplers shall be marked with at least the following:
a) manufacturer’s name,
b) product identification including batch identification, where available,
c) indication of the direction of air flow,
d) shelf life (or expiry date), and
e) number of this document.
NOTE The marking with the number of this document implies only that the sampler fulfils the requirements
given in 6.2.
If required due to limited space, the marking may be placed on the packaging of the sampler. However,
at least the product identification, batch identification, where available, and direction of air flow shall
be indicated on the sampler.
6.2.6 Instructions for use
The instructions for use supplied with the sampler shall be written in the principal language(s) used in
the countries where the sampler is to be marketed. They shall contain at least the following information:
a) designated use (general purpose for a number of gases and vapours or, specific, for a particular gas
or vapour, see 6.1),
b) assurance that blank value meets specifications, where necessary for a particular gas or vapour,
(where a blank value is important),
c) directions for proper handling of the sampler, including opening and closing,
d) general information on the principle of use, for example, sorbent type, reaction of the reagent
impregnated solid, desorption method,
e) information on the range of temperature where the sampler can be used,
f) information on storage and transport, and
g) information on health or environmental hazards and method of disposal.
6.3 Measuring procedure requirements
6.3.1 Sampling procedure requirements
6.3.1.1 General
Sampling conditions (sample volume, flow rate and sampling time) shall be established according to
the LV assigned to the compounds of interest, for example, short-term limit value, long-term limit value
or both.
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6.3.1.2 Sample volume
The recommended sample volume which is calculated from the recommended flow rate and the
reference period should conform to the sampler capacity verification test (see 8.3.1.2).
6.3.1.3 Air flow rate
6.3.1.3.1 Determination of the maximum air flow rate (only for impregnated filters)
When tested according to 8.3.1.4, the maximum air flow rate shall be 90 % of the flow rate at which the
breakthrough volume drops by 5 %.
6.3.1.3.2 Determination of the minimum air flow rate (only for thermal desorption)
A minimum air flow rate shall be established according to the test given in 8.3.1.5.
6.3.1.4 Storage conditions after sampling
The storage conditions after sampling shall be specified. When tested in accordance with 8.3.1.6, the
mean value of the method recovery after storage shall not differ by more than 10 % from the value
before storage.
6.3.2 Analytical procedure requirements
6.3.2.1 Limit of quantification
The limit of quantification shall be lower than or equal to the calculated mass of analyte that would be
collected for the minimum air sample volume specified in the measuring procedure at the following
concentrations:
— 0,1 LV for substances with long­term limit value,
— 0,5 LV for substances with short-term limit value only.
6.3.2.2 Analytical recovery
When tested in accordance with 8.3.2.2, the analytical recovery R shall be
an
— for Type A samplers, R ≥ 75 % with K ≤ 10 % at each loading, and
an v
— for Type B samplers, R ≥ 95 % with K ≤ 10 % at each loading.
an v
The values given for analytical recovery are targets; lower values may be used provided equivalent
precision is achieved.
6.3.2.3 Blank value
In order to obtain acceptable values for the limit of quantification of the method, the blank value of the
sampling media should be as low as technically possible.
When tested in accordance with 8.3.2.3 the blank value shall be less than one­tenth of the calculated
mass collected by the sampler during the recommended sampling time at the recommended air flow
rate and at concentrations of
— 0,1 LV for substances with long­term limit value, and
— 0,5 LV for substances with short-term limit value only.
NOTE Higher blank values can be allowed provided the requirement of 6.3.2.1 is met.
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Where it is known that the blank value is significant and varies between batches of samplers, it shall be
checked regularly.
In order to eliminate any contamination which could occur during storage before use, Type B samplers
should be cleaned by taking them through the thermal desorption procedure. This cleaning process
should be carried out as close as possible to the time when the samplers will be used.
6.3.3 Expanded uncertainty
When tested in accordance with 8.3 the expanded uncerta
...

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