ISO/TS 19807-2:2021

Nanotechnologies — Magnetic nanomaterials — Part 2: Specification of characteristics and measurement methods for nanostructured magnetic beads for nucleic acid extraction

This document specifies characteristics to be measured of magnetic beads in suspension and powder forms for nucleic acid extraction applications. This document deals with magnetic beads that contain a substantial amount of magnetic nanoparticles (which can be superparamagnetic). Potential applicable measurement methods are listed for the individual characteristics. Specifically, this document lists critical characteristics of magnetic beads and suspensions, and additional characteristics to describe the magnetic beads and the suspension for nucleic acid extraction. Health, safety and environmental aspects of magnetic beads are not within the scope of this document.

Nanotechnologies — Nanomatériaux magnétiques — Partie 2: Spécification des caractéristiques et des méthodes de mesure pour les billes magnétiques nanostructurées pour l’extraction d’acide nucléïque

General Information

• Status: Published
• Publication Date: 24-Oct-2021
• ICS: 07.120 - Nanotechnologies
• Technical Committee: ISO/TC 229 - Nanotechnologies
• Drafting Committee: ISO/TC 229/WG 4 - Material specifications
• Current Stage: 6060 - International Standard published
• Start Date: 25-Oct-2021
• Due Date: 25-Sep-2021
• Completion Date: 25-Oct-2021

Standards Content (Sample)

TECHNICAL ISO/TS
SPECIFICATION 19807-2
First edition
2021-10
Nanotechnologies — Magnetic
nanomaterials —
Part 2:
Specification of characteristics
and measurement methods for
nanostructured magnetic beads for
nucleic acid extraction
Nanotechnologies — Nanomatériaux magnétiques —
Partie 2: Spécification des caractéristiques et des méthodes de mesure
pour les billes magnétiques nanostructurées pour l’extraction d’acide
nucléïque
Reference number
ISO/TS 19807-2:2021(E)
© ISO 2021

---------------------- Page: 1 ----------------------
ISO/TS 19807-2:2021(E)
COPYRIGHT PROTECTED DOCUMENT
© ISO 2021
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may
be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting on
the internet or an intranet, without prior written permission. Permission can be requested from either ISO at the address below
or ISO’s member body in the country of the requester.
ISO copyright office
CP 401 • Ch. de Blandonnet 8
CH-1214 Vernier, Geneva
Phone: [phone]
Email: [e-mail]
Website: www.iso.org
Published in Switzerland
ii
  © ISO 2021 – All rights reserved

---------------------- Page: 2 ----------------------
ISO/TS 19807-2:2021(E)
Contents Page
Foreword .iv
Introduction .v
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Abbreviations . 3
5 Characteristics to be measured and measurement methods . 4
5.1 General . 4
5.2 Descriptions of characteristics and their measurement methods . 5
5.2.1 Bead mass concentration . 5
5.2.2 Bead size distribution . 5
5.2.3 Nucleic acid binding capacity . 5
5.2.4 Remanent mass magnetization . 6
5.2.5 Surface functional group type . 7
5.2.6 Saturation mass magnetization . 7
5.2.7 Initial magnetic mass susceptibility . 8
5.2.8 Iron ion concentration . 8
5.2.9 Mass specific surface area . 8
5.2.10 Size of primary magnetic nanoparticles . 9
5.2.11 Surface functional group density .
...

TECHNICAL ISO/TS
SPECIFICATION 19807-2
First edition
Nanotechnologies — Magnetic
nanomaterials —
Part 2:
Specification of characteristics
and measurement methods for
nanostructured magnetic beads for
nucleic acid extraction
Nanotechnologies — Nanomatériaux magnétiques —
Partie 2: Spécification des caractéristiques et des méthodes de mesure
pour les billes magnétiques nanostructurées pour l’extraction d’acide
nucléïque
PROOF/ÉPREUVE
Reference number
ISO/TS 19807-2:2021(E)
©
ISO 2021

---------------------- Page: 1 ----------------------
ISO/TS 19807-2:2021(E)

COPYRIGHT PROTECTED DOCUMENT
© ISO 2021
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may
be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting
on the internet or an intranet, without prior written permission. Permission can be requested from either ISO at the address
below or ISO’s member body in the country of the requester.
ISO copyright office
CP 401 • Ch. de Blandonnet 8
CH-1214 Vernier, Geneva
Phone: [phone]
Email: [e-mail]
Website: www.iso.org
Published in Switzerland
ii PROOF/ÉPREUVE © ISO 2021 – All rights reserved

---------------------- Page: 2 ----------------------
ISO/TS 19807-2:2021(E)

Contents Page
Foreword .iv
Introduction .v
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Abbreviations. 3
5 Characteristics to be measured and measurement methods . 4
5.1 General . 4
5.2 Descriptions of characteristics and their measurement methods . 5
5.2.1 Bead mass concentration . 5
5.2.2 Bead size distribution . . 5
5.2.3 Nucleic acid binding capacity . 5
5.2.4 Remanent mass magnetization . 6
5.2.5 Surface functional group type . 7
5.2.6 Saturation mass magnetization . 7
5.2.7 Initial magnetic mass susceptibility . 8
5.2.8 Iron ion concentration . 8
5.2.9 Mass specific surface area . 8
5.2.10 Size of primary magnetic nanoparticles . 9
5.2.11 Surface functional group density .
...