SIST EN ISO 16664:2008

Gas analysis - Handling of calibration gases and gas mixtures - Guidelines (ISO 16664:2004)

This International Standard describes factors that may influence the composition of pure gases and homogeneous gas mixtures used for calibration purposes. This International Standard only applies to gases or gas mixtures that are within the utilization period , and it pays special attention to; - storage of calibration gas cylinders; - calibration gas withdrawal from cylinders; - transfer of calibration gas from cylinders to the point of calibration. It also outlines a method of assessing the stability for a gas mixture, and takes into account the gas composition uncertainty given on the certificate and the users measurement uncertainty.

Gasanalyse - Handhabung von Kalibriergasen und Gasgemischen - Richtlinien (ISO 16664:2004)

Diese Internationale Norm beschreibt Faktoren, die die Zusammensetzung von reinen Gasen und homogenen
Gasgemischen, die für Kalibrierzwecke verwendet werden, beeinflussen können. Diese Internationale Norm
betrifft ausschließlich Gase und Gasgemische innerhalb ihres „Verwendungszeitraums“ unter besonderer
Berücksichtigung
⎯ der Lagerung von Kalibriergasflaschen,
⎯ der Entnahme von Kalibriergas aus Flaschen,
⎯ dem Transfer von Kalibriergas aus Flaschen zur Kalibrierstelle.
Des Weiteren enthält die Norm eine Kurzbeschreibung eines Verfahrens zur Beurteilung der Stabilität eines
Gasgemischs, und sie berücksichtigt die im Zertifikat angegebene Unsicherheit der Zusammensetzung des
Gases und die Messunsicherheit des Anwenders.

Analyse des gaz - Manutention des gaz et des mélanges de gaz pour étalonnage - Lignes directrices (ISO 16664:2004)

L'ISO 16664:2004 décrit les facteurs susceptibles d'influencer la composition des gaz purs et des mélanges de gaz homogènes utilisés à des fins d'étalonnage. L'ISO 16664:2004 ne s'applique qu'aux gaz ou mélanges de gaz considérés dans les limites de la «période d'utilisation» et elle concerne plus particulièrement:
le stockage des bouteilles de gaz d'étalonnage;
le soutirage du gaz d'étalonnage des bouteilles;
le transfert du gaz d'étalonnage des bouteilles vers le point d'étalonnage.
Elle présente également une méthode permettant d'évaluer la stabilité d'un mélange de gaz et tient compte de l'incertitude de la composition du gaz mentionnée sur le certificat et de l'incertitude de mesure liée à l'utilisateur.

Analiza plinov - Ravnanje s kalibracijskimi plini in plinskimi zmesmi - Smernice (ISO 16664:2004)

General Information

• Status: Withdrawn
• Publication Date: 04-Sep-2008
• Withdrawal Date: 11-Jul-2017
• ICS: 71.040.40 - Chemical analysis
• Technical Committee: NAD - Petroleum products, lubricants and related products
• Current Stage: 9900 - Withdrawal (Adopted Project)
• Start Date: 11-Jul-2017
• Due Date: 03-Aug-2017
• Completion Date: 12-Jul-2017
• Ref Project: EN ISO 16664:2008 - Gas analysis - Handling of calibration gases and gas mixtures - Guidelines (ISO 16664:2004)

Relations

• Replaced By: SIST EN ISO 16664:2017 - Gas analysis - Handling of calibration gases and gas mixtures - Guidelines (ISO 16664:2017)
• Effective Date: 01-Sep-2017

Standards Content (Sample)

SLOVENSKI STANDARD
SIST EN ISO 16664:2008
01-oktober-2008
Analiza plinov - Ravnanje s kalibracijskimi plini in plinskimi zmesmi - Smernice
(ISO 16664:2004)
Gas analysis - Handling of calibration gases and gas mixtures - Guidelines (ISO
16664:2004)
Gasanalyse - Handhabung von Kalibriergasen und Gasgemischen - Richtlinien (ISO
16664:2004)
Analyse des gaz - Manutention des gaz et des mélanges de gaz pour étalonnage -
Lignes directrices (ISO 16664:2004)
Ta slovenski standard je istoveten z: EN ISO 16664:2008
ICS:
71.040.40 Kemijska analiza Chemical analysis
SIST EN ISO 16664:2008 en
2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.

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SIST EN ISO 16664:2008

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SIST EN ISO 16664:2008
EUROPEAN STANDARD
EN ISO 16664
NORME EUROPÉENNE
EUROPÄISCHE NORM
August 2008
ICS 71.040.40

English Version
Gas analysis - Handling of calibration gases and gas mixtures -
Guidelines (ISO 16664:2004)
Analyse des gaz - Manutention des gaz et des mélanges Gasanalyse - Handhabung von Kalibriergasen und
de gaz pour étalonnage - Lignes directrices (ISO Gasgemischen - Richtlinien (ISO 16664:2004)
16664:2004)
This European Standard was approved by CEN on 30 July 2008.
CEN members are bound to comply with the CEN/CENELEC Internal Regulations which stipulate the conditions for giving this European
Standard the status of a national standard without any alteration. Up-to-date lists and bibliographical references concerning such national
standards may be obtained on application to the CEN Management Centre or to any CEN member.
This European Standard exists in three official versions (English, French, German). A version in any other language made by translation
under the responsibility of a CEN member into its own language and notified to the CEN Management Centre has the same status as the
official versions.
CEN members are the national standards bodies of Austria, Belgium, Bulgaria, Cyprus, Czech Republic, Denmark, Estonia, Finland,
France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal,
Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland and United Kingdom.
EUROPEAN COMMITTEE FOR STANDARDIZATION
COMITÉ EUROPÉEN DE NORMALISATION
EUROPÄISCHES KOMITEE FÜR NORMUNG
Management Centre: rue de Stassart, 36  B-1050 Brussels
© 2008 CEN All rights of exploitation in any form and by any means reserved Ref. No. EN ISO 16664:2008: E
worldwide for CEN national Members.

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SIST EN ISO 16664:2008
EN ISO 16664:2008 (E)
Contents Page
Foreword.3

2

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SIST EN ISO 16664:2008
EN ISO 16664:2008 (E)
Foreword
The text of ISO 16664:2004 has been prepared by Technical Committee ISO/TC 158 “Analysis of gases” of
the International Organization for Standardization (ISO) and has been taken over as EN ISO 16664:2008 by
Technical Committee CEN/SS N21 “Gaseous fuels and combustible gas” the secretariat of which is held by
CMC.
This European Standard shall be given the status of a national standard, either by publication of an identical
text or by endorsement, at the latest by February 2009, and conflicting national standards shall be withdrawn
at the latest by February 2009.
Attention is drawn to the possibility that some of the elements of this document may be the subject of patent
rights. CEN [and/or CENELEC] shall not be held responsible for identifying any or all such patent rights.
According to the CEN/CENELEC Internal Regulations, the national standards organizations of the following
countries are bound to implement this European Standard: Austria, Belgium, Bulgaria, Cyprus, Czech
Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia,
Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain,
Sweden, Switzerland and the United Kingdom.
Endorsement notice
The text of ISO 16664:2004 has been approved by CEN as a EN ISO 16664:2008 without any modification.

3

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SIST EN ISO 16664:2008

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SIST EN ISO 16664:2008


INTERNATIONAL ISO
STANDARD 16664
First edition
2004-07-15


Gas analysis — Handling of calibration
gases and gas mixtures — Guidelines
Analyse des gaz — Manutention des gaz et des mélanges de gaz pour
étalonnage — Lignes directrices




Reference number
ISO 16664:2004(E)
©
ISO 2004

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SIST EN ISO 16664:2008
ISO 16664:2004(E)
PDF disclaimer
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©  ISO 2004
All rights reserved. Unless otherwise specified, no part of this publication may be reproduced or utilized in any form or by any means,
electronic or mechanical, including photocopying and microfilm, without permission in writing from either ISO at the address below or
ISO's member body in the country of the requester.
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Published in Switzerland

ii © ISO 2004 – All rights reserved

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SIST EN ISO 16664:2008
ISO 16664:2004(E)
Contents Page
Foreword. iv
Introduction . v
1 Scope. 1
2 Terms and definitions. 1
3 Transport and storage . 4
3.1 General remarks. 4
3.2 Low temperature. 4
3.3 High temperature. 4
3.4 Water. 4
3.5 Storage and handling. 4
4 Mode of withdrawal. 5
4.1 General. 5
4.2 Minimum utilization pressure . 5
4.3 Temperature. 5
4.4 Pressure reduction and flow. 5
4.5 Replacement, change of cylinder positions. 5
5 Transfer system. 6
5.1 Purging procedure. 6
5.2 Considerations when designing and constructing gas transfer lines . 7
6 Stability. 13
Annex A (informative) Check on the stability of calibration gas mixtures by end-users . 14
Bibliography . 17

© ISO 2004 – All rights reserved iii

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SIST EN ISO 16664:2008
ISO 16664:2004(E)
Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards bodies
(ISO member bodies). The work of preparing International Standards is normally carried out through ISO
technical committees. Each member body interested in a subject for which a technical committee has been
established has the right to be represented on that committee. International organizations, governmental and
non-governmental, in liaison with ISO, also take part in the work. ISO collaborates closely with the
International Electrotechnical Commission (IEC) on all matters of electrotechnical standardization.
International Standards are drafted in accordance with the rules given in the ISO/IEC Directives, Part 2.
The main task of technical committees is to prepare International Standards. Draft International Standards
adopted by the technical committees are circulated to the member bodies for voting. Publication as an
International Standard requires approval by at least 75 % of the member bodies casting a vote.
Attention is drawn to the possibility that some of the elements of this document may be the subject of patent
rights. ISO shall not be held responsible for identifying any or all such patent rights.
ISO 16664 was prepared by Technical Committee ISO/TC 158, Analysis of gases.
iv © ISO 2004 – All rights reserved

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SIST EN ISO 16664:2008
ISO 16664:2004(E)
Introduction
This International Standard uses the terms “calibration gas” for both gas mixtures and pure gases as the
limiting case of gas mixtures.
The quality of calibration gases in cylinders as certified by producers is defined by
a) the correct analyte content;
b) a known uncertainty which is appropriate for its intended use;
c) the stability;
d) the homogeneity.
During its utilization period, the quality of calibration gases is influenced by
 storage conditions at the manufacturer’s and user’s sites;
 transport conditions;
 modes of calibration gas withdrawal and transfer;
 the transfer system employed.
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SIST EN ISO 16664:2008

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SIST EN ISO 16664:2008
INTERNATIONAL STANDARD ISO 16664:2004(E)

Gas analysis — Handling of calibration gases and gas
mixtures — Guidelines
SAFETY PRECAUTIONS — National and International safety regulations concerning storage, use and
transportation of pure gases and gas mixtures are to be followed in addition to this International
Standard.
1 Scope
This International Standard describes factors that may influence the composition of pure gases and
homogeneous gas mixtures used for calibration purposes. This International Standard only applies to gases or
gas mixtures that are within the “utilization period”, and it pays special attention to
 storage of calibration gas cylinders;
 calibration gas withdrawal from cylinders;
 transfer of calibration gas from cylinders to the point of calibration.
It also outlines a method of assessing the stability for a gas mixture, and takes into account the gas
composition uncertainty given on the certificate and the users measurement uncertainty.
2 Terms and definitions
For the purposes of this document, the following terms and definitions apply.
2.1
calibration gas
pure gas or gas mixture used for calibration
2.2
calibration gas mixture
gas mixture of sufficient stability and homogeneity whose composition is properly established for use in the
calibration of a measuring instrument or for the validation of a measurement or gas analytical method
[ISO 7504:2001]
2.3
component
chemical substance present in, or a material used in the preparation of, a gas mixture
NOTE 1 In practice, the term component is used variously to mean either:
a) a distinct pure chemical substance; or
b) a material such as:
 a pure substance mixed with small amounts of inadvertent impurities,
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SIST EN ISO 16664:2008
ISO 16664:2004(E)
 a well defined mixture, such as air,
 a less well defined mixture, such as natural gas.
NOTE 2 In circumstances where it is required to distinguish unambiguously between the individual distinct chemical
substances present in a gas mixture and the materials used in gas mixture preparation, then the chemical substances
shall be referred to as “constituents”. When a constituent is or has been the subject of quantitative analysis, it may be
referred to as an “analyte”.
NOTE 3 In the preparation of gas mixtures, materials such as gases, vapours and gas mixtures, including their
impurities, are sometimes called “parent gases”.
[ISO 7504:2001]
2.4
homogeneity
state of a gas mixture wherein all of its components are distributed uniformly throughout the volume occupied
by the gas mixture
NOTE Unless any other indication is given, it is normally to be assumed that the gas mixture is homogeneous with
respect to composition and properties at all points in the gas mixture.
[ISO 7504:2001]
2.5
impurity
component present, but not wanted, in a gas mixture
NOTE 1 Impurities found in a gas mixture originate from the parent gases or are introduced during or after its
production.
NOTE 2 An impurity affecting the intended use of a gas mixture is called a “critical impurity”.
NOTE 3 If the fraction of a gas mixture component is close to unity, and if the other components are of no special
interest, such a gas mixture is considered, in general, as a “pure gas” consisting of that predominant component
containing some impurities.
NOTE 4 The “purity” of a “pure gas” is quantified usually by the difference between unity and the sum of the fractions of
all specified impurities.
[adapted from ISO 7504:2001]
2.6
leak rate
volume of fluid leaking from the system per unit of time due to incomplete sealing of materials
2.7
leak tightness
conformity to a specified leak rate
2.8
response time
time interval between the instant when a stimulus is subjected to a specified abrupt change and the instant
when the response reaches and remains within specified limits around its final steady value
[VIM]
2 © ISO 2004 – All rights reserved

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SIST EN ISO 16664:2008
ISO 16664:2004(E)
2.9
stability
attribute of a gas mixture, stored or used under specified conditions, to maintain its composition within
specified uncertainty limits for a specified period of time (maximum storage life) and over a specified range of
pressure and of temperature
NOTE It is appropriate to specify the uncertainty limits for each component of interest.
[ISO 7504:2001]
2.10
maximum storage life
period after which the stored gas mixture shall not be used
NOTE 1 This period is usually identified as that for which the producer assures that the gas mixture maintains its
composition within the specified limits when it is stored in accordance with requirements based upon maximum filling
pressure, minimum utilization pressure, and minimum and maximum applicable temperature.
NOTE 2 The end of this period may be indicated by an “expiry date”.
[ISO 7504:2001]
2.11
transfer system
gas-conducting system which begins at the cylinder valve and ends at the gas sample inlet to the measuring
instrument and includes all structural elements
2.12
uncertainty
〈measurement〉 parameter, associated with the result of a measurement, that characterizes the dispersion of
the values that could reasonably be attributed to the measurand
NOTE 1 The parameter may be, for example, a standard deviation or a given multiple of it, or the half-width of an
interval having a stated level of confidence.
NOTE 2 Uncertainty of measurement comprises, in general, many components. Some of these components may be
evaluated from the statistical distribution of the results of series of measurements and can be characterized by
experimental standard deviations. The other components, which also can be characterized by standard deviations, are
evaluated from assumed probability distributions based on experience or other information.
NOTE 3 It is understood that the result of a measurement is the best estimate of the value of a measurand, and that all
components of uncertainty, including those arising from systematic effects, such as components associated with
corrections and reference standards, contribute to the dispersion.
[GUM; ISO 7504:2001]
2.13
utilization period
time between the date of certification and the expiry date
2.14
permeability
property of a material of transmitting gases and liquids by passage through one surface and out at another
surface by diffusion and sorption processes
NOTE Not to be confused with porosity.
[ISO 472:1999]
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SIST EN ISO 16664:2008
ISO 16664:2004(E)
3 Transport and storage
3.1 General remarks
After preparation of the calibration gas, the gas cylinder will be transported to the user. The environment in
which the cylinders are transported is not normally regulated in terms of temperature and humidity. Low
temperatures may have a detrimental impact on the mixture composition, especially when condensable
components are present in the mixture. As a consequence of this, environmental conditions during transport
and storage should never exceed those recommended by the manufacturer.
Gas cylinders and especially cylinder valves shall be free of grease and other lubricants. During storage and
transportation, cylinder valves shall be closed, sealing nuts shall be tightened and protection caps shall be
attached.
The gas cylinders are transported in several ways, e.g. by air, railway, road and on water. In some specific
cases, the temperature restrictions may be such that not every means of transport is acceptable.
3.2 Low temperature
The gas cylinder may be exposed to low temperatures during storage and transportation. For gas mixtures
containing condensable components, it is important that the cylinder is not stored or transported at
temperatures below those recommended by the manufacturer. If the mixture is exposed to temperatures
below the stated range, some components may condense and this will change the composition of the mixture.
If the mixture has been exposed to temperatures lower than those recommended by the manufacturer, the
certificate from the manufacturer is no longer valid. In this case, it is very important that the mixture shall not
be used before the manufacturer is asked for further advice. He may advise homogenizing the mixture before
usage.
3.3 High temperature
Avoid high temperatures (heating) close to the cylinder, e.g. from welding flames, blowlamps, ovens or other
intensive heat sources. High temperatures will result in higher pressures leading to potentially hazardous
situations. In addition, elevated temperatures may result in decomposition of thermally unstable species.
3.4 Water
Gas cylinders shall be protected from excessive humidity during transport. Transportation by boat may result
in the cylinder being sprayed with water; this and/or excessive humidity may cause corrosion of the cylinder
valve. Always protect the cylinder from precipitation to prevent corrosion. If the cylinders are
...