ISO/TS 21623:2017

Workplace exposure — Assessment of dermal exposure to nano-objects and their aggregates and agglomerates (NOAA)

ISO/TS 21623:2017 describes a systematic approach to assess potential occupational risks related to nano-objects and their agglomerates and aggregates (NOAA) arising from the production and use of nanomaterials and/or nano-enabled products. This approach provides guidance to identify exposure routes, exposed body parts and potential consequences of exposure with respect to skin uptake, local effects and inadvertent ingestion. ISO/TS 21623:2017 also considers occupational use of products containing NOAA by professionals, e.g. beauticians applying personal care products, cosmetics or pharmaceuticals, but does not apply to deliberate or prescribed exposure to these products by consumers. ISO/TS 21623:2017 is aimed at occupational hygienists, researchers and other safety professionals to assist recognition of potential dermal exposure and its potential consequences.

Exposition sur les lieux de travail — Évaluation de l'exposition cutanée aux nano-objets et à leurs agrégats et agglomérats (NOAA)

General Information

• Status: Published
• Publication Date: 23-Nov-2017
• ICS: 13.040.30 - Workplace atmospheres
• Technical Committee: ISO/TC 146/SC 2 - Workplace atmospheres
• Drafting Committee: ISO/TC 146/SC 2/WG 8 - Assessment of contamination of skin and surfaces from airborne chemicals
• Current Stage: 9060 - Close of review
• Start Date: 02-Sep-2027

Relations

• Consolidates: ISO 6621-4:2003 - Internal combustion engines — Piston rings — Part 4: General specifications
• Effective Date: 06-Jun-2022
• Consolidated By: ISO 1628-2:2020 - Plastics — Determination of the viscosity of polymers in dilute solution using capillary viscometers — Part 2: Poly(vinyl chloride) resins
• Effective Date: 06-Jun-2022

Standards Content (Sample)

TECHNICAL ISO/TS
SPECIFICATION 21623
First edition
2017-11
Workplace exposure — Assessment
of dermal exposure to nano-
objects and their aggregates and
agglomerates (NOAA)
Exposition sur les lieux de travail — Évaluation de l'exposition
cutanée aux nano-objets et à leurs agrégats et agglomérats (NOAA)
Reference number
ISO/TS 21623:2017(E)
©
ISO 2017

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ISO/TS 21623:2017(E)

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ii © ISO 2017 – All rights reserved

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ISO/TS 21623:2017(E)

Contents Page
Foreword .iv
Introduction .v
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Dermal exposure to NOAA — Evidence and exposure routes . 4
4.1 General . 4
4.2 Source domains . 4
4.3 Exposure routes . 5
5 Stepwise approach for assessment of dermal exposure to NOAA . 6
5.1 General . 6
5.2 Step 1: Desk evaluation . 7
5.2.1 Step 1A: Evaluation of toxicological hazard based on NOAA composition . 7
5.2.2 Step 1B: Screening for potential risks associated with dermal exposure to
insoluble (non-flexible) NOAA . 8
5.2.3 Step 1C: Screening for potential risks associated with dermal exposure
based on job title . .10
5.3 Step 2: Observation of potential for dermal exposure .11
5.4 Step 3: Additional observation of worker behaviour.11
5.5 Step 4: Quantification of NOAA .11
5.6 Step 5: Evaluation and review .12
Annex A (informative) Industries associated with use of nanomaterials or nano-
enabled products .
...