SIST EN ISO 21253-1:2020

Water quality - Multi-compound class methods - Part 1: Criteria for the identification of target compounds by gas and liquid chromatography and mass spectrometry (ISO 21253-1:2019)

This document specifies the criteria for mass spectrometric identification of target compounds in water samples and is applicable to environmental samples in general. This document is intended to be used in conjunction with standards developed for the determination of specific compounds. If a standard method for analysing specific compounds includes criteria for identification, those criteria are followed.

Wasserbeschaffenheit - Gemeinsam erfassbare Stoffgruppen - Teil 1: Kriterien für die Identifizierung von Zielverbindungen mittels Gaschromatographie und Flüssigchromatographie mit Massenspektrometrie-Kopplung (ISO 21253-1:2019)

Dieses Dokument legt Kriterien für die massenspektrometrische Identifizierung von Zielverbindungen in Wasserproben fest und ist im Allgemeinen auf Umweltproben anwendbar. Dieses Dokument ist für die Anwendung in Verbindung mit einer Norm vorgesehen, die für die Bestimmung bestimmter Verbindungen entwickelt wurde. Wenn ein genormtes Verfahren für die Analyse bestimmter Verbindungen Kriterien für die Identifizierung enthält, dann sind diese Kriterien zu befolgen.

Qualité de l'eau - Méthodes d'analyse de composés multi-classes - Partie 1: Critères pour l'identification des composées cibles par chromatographie en phase gazeuse et liquide et spectrométrie de masse (ISO 21253-1:2019)

Le présent document spécifie des critères pour l'identification par spectrométrie de masse de composés cibles dans des échantillons d'eau et est applicable aux échantillons environnementaux en général. Le présent document est destiné à être utilisé en association avec des normes élaborées pour permettre la détermination de composés spécifiques. Si une méthode normalisée d'analyse de composés spécifiques inclut des critères d'identification, ces critères sont appliqués.

Kakovost vode - Metode za več spojin - 1. del: Merila za identifikacijo ciljnih spojin s plinsko in tekočinsko kromatografijo ter masno spektrometrijo (ISO 21253-1:2019)

Ta mednarodni standard podaja merila za identifikacijo ciljnih spojin v vodi na podlagi masne spektrometrije. Ta dokument je smernica za identifikacijo molekul < 1200 Da. Za identifikacijo večjih molekul so priporočene dodatne preiskave. Ta standard se uporablja skupaj s standardi, pripravljenimi za določanje specifičnih spojin. Če standardi za analizo določenih spojin podajajo merila za identifikacijo, je treba ta merila upoštevati.

General Information

• Status: Published
• Public Enquiry End Date: 02-Jan-2019
• Publication Date: 02-Dec-2019
• ICS: 13.060.50 - Examination of water for chemical substances
• ICS: 71.040.50 - Physicochemical methods of analysis
• Technical Committee: KAV - Water quality
• Current Stage: 6060 - National Implementation/Publication (Adopted Project)
• Start Date: 11-Nov-2019
• Due Date: 16-Jan-2020
• Completion Date: 03-Dec-2019
• Ref Project: EN ISO 21253-1:2019 - Water quality - Multi-compound class methods - Part 1: Criteria for the identification of target compounds by gas and liquid chromatography and mass spectrometry (ISO 21253-1:2019)

Standards Content (Sample)

SLOVENSKI STANDARD
01-januar-2020
Kakovost vode - Metode za več spojin - 1. del: Merila za identifikacijo ciljnih spojin
s plinsko in tekočinsko kromatografijo ter masno spektrometrijo (ISO 21253-
1:2019)
Water quality - Multi-compound class methods - Part 1: Criteria for the identification of
target compounds by gas and liquid chromatography and mass spectrometry (ISO 21253
-1:2019)
Wasserbeschaffenheit - Gemeinsam erfassbare Stoffgruppen - Teil 1: Kriterien für die
Identifizierung von Zielverbindungen mittels Gaschromatographie und
Flüssigchromatographie mit Massenspektrometrie-Kopplung (ISO 21253-1:2019)
Qualité de l'eau - Méthodes d'analyse de composés multi-classes - Partie 1: Critères
pour l'identification des composées cibles par chromatographie en phase gazeuse et
liquide et spectrométrie de masse (ISO 21253-1:2019)
Ta slovenski standard je istoveten z: EN ISO 21253-1:2019
ICS:
13.060.50 Preiskava vode na kemične Examination of water for
snovi chemical substances
71.040.50 Fizikalnokemijske analitske Physicochemical methods of
metode analysis
2003-01.Slovenski inštitut za standardizacijo. Razmnoževanje celote ali delov tega standarda ni dovoljeno.

EN ISO 21253-1
EUROPEAN STANDARD
NORME EUROPÉENNE
October 2019
EUROPÄISCHE NORM
ICS 13.060.50
English Version
Water quality - Multi-compound class methods - Part 1:
Criteria for the identification of target compounds by gas
and liquid chromatography and mass spectrometry (ISO
21253-1:2019)
Qualité de l'eau - Méthodes d'analyse de composés Wasserbeschaffenheit - Gemeinsam erfassbare
multi-classes - Partie 1: Critères pour l'identification Stoffgruppen - Teil 1: Kriterien für die Identifizierung
des composées cibles par chromatographie en phase von Zielverbindungen mittels Gaschromatographie und
gazeuse et liquide et spectrométrie de masse (ISO Flüssigchromatographie mit Massenspektrometrie-
21253-1:2019) Kopplung (ISO 21253-1:2019)
This European Standard was approved by CEN on 9 August 2019.

CEN members are bound to comply with the CEN/CENELEC Internal Regulations which stipulate the conditions for giving this
European Standard the status of a national standard without any alteration. Up-to-date lists and bibliographical references
concerning such national standards may be obtained on application to the CEN-CENELEC Management Centre or to any CEN
member.
This European Standard exists in three official versions (English, French, German). A version in any other language made by
translation under the responsibility of a CEN member into its own language and notified to the CEN-CENELEC Management
Centre has the same status as the official versions.

CEN members are the national standards bodies of Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia,
Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway,
Poland, Portugal, Republic of North Macedonia, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey and
United Kingdom.
EUROPEAN COMMITTEE FOR STANDARDIZATION
COMITÉ EUROPÉEN DE NORMALISATION

EUROPÄISCHES KOMITEE FÜR NORMUNG

CEN-CENELEC Management Centre: Rue de la Science 23, B-1040 Brussels
© 2019 CEN All rights of exploitation in any form and by any means reserved Ref. No. EN ISO 21253-1:2019 E
worldwide for CEN national Members.

Contents Page
European foreword . 3

European foreword
This document (EN ISO 21253-1:2019) has been prepared by Technical Committee ISO/TC 147 "Water
quality" in collaboration with Technical Committee CEN/TC 230 “Water analysis” the secretariat of
which is held by DIN.
This European Standard shall be given the status of a national standard, either by publication of an
identical text or by endorsement, at the latest by April 2020, and conflicting national standards shall be
withdrawn at the latest by April 2020.
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. CEN shall not be held responsible for identifying any or all such patent rights.
According to the CEN-CENELEC Internal Regulations, the national standards organizations of the
following countries are bound to implement this European Standard: Austria, Belgium, Bulgaria,
Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland,
Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, Netherlands, Norway, Poland, Portugal, Republic of
North Macedonia, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland, Turkey and the
United Kingdom.
Endorsement notice
The text of ISO 21253-1:2019 has been approved by CEN as EN ISO 21253-1:2019 without any
modification.
INTERNATIONAL ISO
STANDARD 21253-1
First edition
2019-08
Water quality — Multi-compound
class methods —
Part 1:
Criteria for the identification of
target compounds by gas and
liquid chromatography and mass
spectrometry
Qualité de l'eau — Méthodes d'analyse de composés multi-classes —
Partie 1: Critères pour l'identification de composées cibles par
chromatographie en phase gazeuse ou liquide et spectrométrie de
masse
Reference number
ISO 21253-1:2019(E)
©
ISO 2019
ISO 21253-1:2019(E)
© ISO 2019
All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may
be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting
on the internet or an intranet, without prior written permission. Permission can be requested from either ISO at the address
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ISO copyright office
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Published in Switzerland
ii © ISO 2019 – All rights reserved

ISO 21253-1:2019(E)
Contents Page
Foreword .iv
Introduction .v
1 Scope . 1
2 Normative references . 1
3 Terms and definitions . 1
4 Abbreviated terms . 2
5 Principle . 3
6 Apparatus . 3
7 Identification of target compounds . 4
7.1 Procedure for identification of organic compounds with chromatography-mass
spectrometry . 4
7.2 Step 1: Chromatographic separation . 5
7.3 Step 2: Mass spectrometric evaluation . 6
7.3.1 Mass spectrometric detection . 6
7.3.2 Selection of diagnostic ions . 6
7.3.3 Assigning identification points . 7
7.4 Step 3: Additional analytical confirmation evaluation . 8
7.5 Reporting the presence of target compounds . 9
7.5.1 Identification . 9
7.5.2 Indication . 9
7.5.3 Absence of the target compounds ( 8 Test report . 9
Annex A (informative) Recommendations for the most commonly used techniques .10
Annex B (normative) Criteria for full scan measurement .12
n n
Annex C (informative) Diagnostic ions to be used for identification using GC-MS and LC-MS .13
Annex D (informative) Examples of calculating identification points .14
Bibliography .21
ISO 21253-1:2019(E)
Foreword
ISO (the International Organization for Standardization) is a worldwide federation of national standards
bodies (ISO member bodies). The work of preparing International Standards is normally carried out
through ISO technical committees. Each member body interested in a subject for which a technical
committee has been established has the right to be represented on that committee. International
organizations, governmental and non-governmental, in liaison with ISO, also take part in the work.
ISO collaborates closely with the International Electrotechnical Commission (IEC) on all matters of
electrotechnical standardization.
The procedures used to develop this document and those intended for its further maintenance are
described in the ISO/IEC Directives, Part 1. In particular the different approval criteria needed for the
different types of ISO documents should be noted. This document was drafted in accordance with the
editorial rules of the ISO/IEC Directives, Part 2 (see www .iso .org/directives).
Attention is drawn to the possibility that some of the elements of this document may be the subject of
patent rights. ISO shall not be held responsible for identifying any or all such patent rights. Details of
any patent rights identified during the development of the document will be in the Introduction and/or
on the ISO list of patent declarations received (see www .iso .org/patents).
Any trade name used in this document is information given for the convenience of users and does not
constitute an endorsement.
For an explanation on the voluntary nature of standards, the meaning of ISO specific terms and
expressions related to conformity assessment, as well as information about ISO's adherence to the
World Trade Organization (WTO) principles in the Technical Barriers to Trade (TBT) see the following
URL: www .iso .org/iso/foreword .html.
This document was prepared by Technical Committee ISO/TC 147, Water quality, Subcommittee SC 2,
Physical, chemical and biochemical methods.
A list of all parts in the ISO 21253 series can be found on the ISO website.
Any feedback or questions on this document should be directed to the user’s national standards body. A
complete listing of these bodies can be found at www .iso .org/members .html.
iv © ISO 2019 – All rights reserved

ISO 21253-1:2019(E)
Introduction
The use of gas chromatography (GC) and liquid chromatography (LC) in combination with mass
spectrometric (MS) detection is common in many analytical standards. This detector is a powerful tool
provided it is properly used. This document gives the criteria for the identification of target compounds
in various types of water. This document shall be used in combination with specific analytical standards
or in combination with any GC-MS and LC-MS procedure. The result of the procedur
...